Parkinson’s Disease Overview
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Questions and Answers

Which stage of Parkinson's disease is characterized by Lewy bodies found in the medulla oblongata, locus coeruleus, raphe nuclei, and olfactory bulb?

  • Stage 4 of Hoehn & Yahr staging
  • Advanced stage
  • Motor stage
  • Premotor stage (correct)
  • Which stage of Hoehn & Yahr staging is characterized by severe disability and the inability to function independently?

  • Stage 5
  • Stage 4 (correct)
  • Stage 1
  • Stage 2
  • Which brain region is affected in the motor stage of Parkinson's disease with the development of motor features?

  • Medulla oblongata
  • Raphe nuclei
  • Midbrain (SNc) (correct)
  • Locus coeruleus
  • What is the typical clinical presentation required for the diagnosis of Parkinson's disease?

    <p>Bradykinesia and resting tremor</p> Signup and view all the answers

    In which stage of Parkinson's disease do Lewy bodies spread to the cortex, potentially leading to cognitive and behavior changes?

    <p>Advanced stage</p> Signup and view all the answers

    Which of the following brain regions is affected during the premotor stage of Parkinson's disease?

    <p>Locus coeruleus</p> Signup and view all the answers

    In which stage of Hoehn & Yahr staging does the disease present as mild/moderate bilateral with some postural instability but still independence?

    <p>Stage 3</p> Signup and view all the answers

    Which nonmotor symptom is required for the clinical diagnosis of Parkinson's disease, in addition to bradykinesia?

    <p>Impaired olfaction</p> Signup and view all the answers

    During which stage of Parkinson's disease does the development of motor features occur as Lewy bodies ascend to the midbrain (SNc)?

    <p>Motor stage</p> Signup and view all the answers

    At which stage of Parkinson's disease are individuals bed/wheelchair bound due to severe disability and the inability to function independently?

    <p>Stage 5</p> Signup and view all the answers

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