Podcast
Questions and Answers
Why are sterile liquid dosage forms via injection beneficial for very ill or comatose patients?
Why are sterile liquid dosage forms via injection beneficial for very ill or comatose patients?
- Drug targeting to specific organs or highly localized effects
- Rapid increase in blood volume (correct)
- Avoidance of gastrointestinal irritation
- Prolonged drug effect with depot injections
What is the primary advantage of sterile liquid dosage forms introduced into the body by injection?
What is the primary advantage of sterile liquid dosage forms introduced into the body by injection?
- Prolonged drug effect with depot injections
- Rapid onset of action and nearly complete bioavailability (correct)
- Drug targeting to specific organs or highly localized effects
- Avoidance of gastrointestinal irritation
What is a potential drawback of sterile liquid dosage forms via injection?
What is a potential drawback of sterile liquid dosage forms via injection?
- Expensive manufacturing requirements
- Presence of contamination causing serious problems
- Painful administration leading to non-compliance (correct)
- Incorrect doses or difficult drug treatments
In what scenario would depot injections be advantageous?
In what scenario would depot injections be advantageous?
Why might sterile liquid dosage forms via injection be unsuitable for some patients?
Why might sterile liquid dosage forms via injection be unsuitable for some patients?
Which method is suitable for sterilizing medical and surgical supplies such as catheters, needles, and plastic disposable syringes in their final plastic packaging just prior to shipment?
Which method is suitable for sterilizing medical and surgical supplies such as catheters, needles, and plastic disposable syringes in their final plastic packaging just prior to shipment?
What is a limitation of bacterial filtration as a sterilization method for medicinal preparations?
What is a limitation of bacterial filtration as a sterilization method for medicinal preparations?
What is the purpose of adding a preservative to multidose injections?
What is the purpose of adding a preservative to multidose injections?
Which type of solution in sealed containers can be readily sterilized by dry heat?
Which type of solution in sealed containers can be readily sterilized by dry heat?
What is a common factor that might affect the effectiveness of medicinal preparations sterilized by bacterial filtration?
What is a common factor that might affect the effectiveness of medicinal preparations sterilized by bacterial filtration?
Study Notes
Sterile Liquid Dosage Forms via Injection
- Sterile liquid dosage forms via injection are beneficial for very ill or comatose patients because they allow for rapid and precise delivery of medication.
- The primary advantage of sterile liquid dosage forms introduced into the body by injection is the rapid onset of action.
- A potential drawback of sterile liquid dosage forms via injection is that they can be painful and may cause tissue damage.
Depot Injections
- Depot injections are advantageous in scenarios where a prolonged release of medication is required.
Limitations of Sterile Liquid Dosage Forms
- Sterile liquid dosage forms via injection may be unsuitable for some patients due to pain or tissue damage concerns.
Sterilization Methods
- Ethylene oxide sterilization is suitable for sterilizing medical and surgical supplies such as catheters, needles, and plastic disposable syringes in their final plastic packaging just prior to shipment.
- A limitation of bacterial filtration as a sterilization method for medicinal preparations is that it may not remove all pyrogens.
Preservatives in Multidose Injections
- The purpose of adding a preservative to multidose injections is to prevent microbial contamination.
Sterilization by Dry Heat
- Aqueous solutions in sealed containers can be readily sterilized by dry heat.
Bacterial Filtration
- A common factor that might affect the effectiveness of medicinal preparations sterilized by bacterial filtration is the filter's pore size and integrity.
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Description
Test your knowledge of sterile liquid dosage forms that are administered through injection into the body. Explore the various applications and benefits of parenteral drug administration.
