Podcast
Questions and Answers
What is the primary objective of the drug discovery phase?
What is the primary objective of the drug discovery phase?
- To identify lead molecules (correct)
- To conduct animal studies
- To obtain marketing authorisation
- To know the key phases of drug discovery and development
What impeded the development of back ups when the lead failed in the historical approach to drug discovery?
What impeded the development of back ups when the lead failed in the historical approach to drug discovery?
- Lack of structural diversity in lead molecules (correct)
- Unknown mechanisms of active molecules
- Toxicity of lead molecules
- Poor pharmacokinetics of lead molecules
How did pharmaceutical industries' success in drug discovery originate in the 1950s and 1960s?
How did pharmaceutical industries' success in drug discovery originate in the 1950s and 1960s?
- Through accidental discovery and chance (correct)
- By optimizing lead molecules
- Through rational structure-based approaches
- By conducting human studies
What was a major limitation of the historical approach to drug discovery in the 20th century?
What was a major limitation of the historical approach to drug discovery in the 20th century?
What did William Withering discover in 1776 through one of his dying patients?
What did William Withering discover in 1776 through one of his dying patients?