10 Questions
Which type of injection is made into the loose tissue beneath the skin?
Subcutaneous or hypodermic injection
What is the main problem in the formulation of parenteral emulsions?
Attainment and maintenance of uniform oil droplets
Which type of pharmacologically parenteral dosage form is dry soluble materials reconstituted prior to use?
Dry insoluble materials reconstituted prior use
What is the route of administration of drugs by injection under or through one or more layers of skin or mucous membrane called?
Parenteral
Which type of injection is made deep into the layers of the muscle?
IM injection
What is the purpose of the leaker test in parenteral quality control?
To determine the efficiency of sealing of ampoules
What is the purpose of using deeply colored dye solution in the leaker test?
To make any opening in the ampoule visible
How is the clarity test in parenteral quality control performed?
By visually inspecting clean containers under good light against a black and white background with swirling action
Why is it important to avoid introducing air bubbles during the clarity test?
Air bubbles can obstruct the view and make it difficult to detect particles
What is the role of a vacuum chamber in the leaker test?
To produce a negative pressure within completely sealed ampoules
Study Notes
Parenteral Dosage Forms
- Subcutaneous injection is made into the loose tissue beneath the skin.
- The main problem in the formulation of parenteral emulsions is the difficulty in achieving a stable and consistent emulsion.
- Dry soluble materials are reconstituted prior to use in lyophilized or powdered parenteral dosage forms.
- The route of administration of drugs by injection under or through one or more layers of skin or mucous membrane is called parenteral administration.
- Intramuscular injection is made deep into the layers of the muscle.
Parenteral Quality Control
- The purpose of the leaker test is to detect leakage in the container or seal of a parenteral product.
- The purpose of using deeply colored dye solution in the leaker test is to enhance the visibility of any leakage.
- The clarity test is performed by visual examination of the product against a white or black background.
- It is important to avoid introducing air bubbles during the clarity test to prevent interference with the visual examination.
- The role of a vacuum chamber in the leaker test is to create a pressure difference to facilitate the detection of leakage.
Test your knowledge of parenteral dosage forms with this quiz. Explore the different types of pharmacologically parenteral formulations and their administration methods. From solutions ready to be injected to reconstituted dry materials, this quiz covers the essentials of parenteral drug delivery.
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