Pantoprazole Flashcards

Questions and Answers

What is the generic name of Pantoprazole?

Pantoprazole

What is the trade name for Pantoprazole?

Protonix

What classification does Pantoprazole fall under?

Proton pump inhibitor

What is the FDA category for Pantoprazole?

B Signup and view all the answers

What is the mechanism of action for Pantoprazole?

Pantoprazole is a proton pump inhibitor (PPI) that suppresses gastric acid production by covalently binding to the (H+, K+)-ATPase enzyme system. Signup and view all the answers

What are the therapeutic uses of Pantoprazole?

It is used to treat erosive esophagitis and other conditions involving excess stomach acid such as GERD. Signup and view all the answers

What is the normal dosage for Pantoprazole?

40 mg Signup and view all the answers

What are some common side effects of Pantoprazole?

Diarrhea, headache, nausea, dyspepsia, and injection site reactions. Signup and view all the answers

What nursing considerations should be taken into account with Pantoprazole?

Elevation of gastric pH may cause pneumonia. Signup and view all the answers

What patient teachings are important for those taking Pantoprazole?

Swallow tablets whole, do not crush, chew, or cut, and report severe diarrhea, headache, or fever. Signup and view all the answers

What laboratory tests should be monitored for patients on Pantoprazole?

Liver function tests Signup and view all the answers

Study Notes

Pantoprazole Overview

Generic name: Pantoprazole; Trade name: Protonix
Classified as a proton pump inhibitor (PPI) which reduces gastric acid production.

FDA Category

Classified as Category B, indicating no proven risk in humans during pregnancy.

Mechanism of Action

Covalently binds to (H+, K+)-ATPase enzyme at gastric parietal cells.
Suppresses both basal and stimulated gastric acid secretion.
Metabolized in the liver; excreted in urine and feces.

Therapeutic Uses

Treats erosive esophagitis and conditions involving excess stomach acid, such as GERD.
Not designed for immediate relief of heartburn symptoms.

Dosage Information

Administered orally (PO) or intravenously (IV).
Delayed release tablets (20 to 40 mg), enteric coated granules (40 mg), powder for injection (40 mg/vial).
Oral doses can be taken with or without food; infusions take 15 minutes with an in-line filter.
Normal dosage is 40 mg; dosage adjustment necessary for hepatic impairment.

Side Effects

Common IV therapy side effects: diarrhea, headache, nausea, dyspepsia, injection site reactions (thrombophlebitis, abscess).
Long-term use risks include hypomagnesemia, osteoporosis, and fractures.
Oral therapy common side effects: diarrhea, headache, dizziness.

Nursing Considerations

Increased gastric pH could elevate pneumonia risk.
Reassess therapy for GERD after four weeks; switch to oral administration when possible.
Consider zinc supplementation during IV therapy in patients at risk for deficiency.

Patient Teaching

Advise to swallow tablets whole; do not crush, chew, or cut.
Instruct to take precautions against dizziness and report severe diarrhea, headache, or fever.

Laboratory Monitoring

Monitor liver function tests to assess liver health during treatment.

Description

Test your knowledge of Pantoprazole with these flashcards. The quiz covers its classification, FDA category, and mechanism of action. Perfect for students and healthcare professionals seeking to understand this important medication.