Medicine II: Final Exam

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128 Questions

Which of the following is a defining feature of Ulcerative Colitis?

Always involves the rectum

What is the age range for the bimodal peak of Ulcerative Colitis?

20s-30s and 50s-60s

Which of the following is NOT a symptom of Ulcerative Colitis?

Constipation

Which of the following is a potential extraintestinal manifestation (EIM) of Ulcerative Colitis?

Swelling of eyes

What is the first-line treatment for Ulcerative Colitis?

5-ASA

What is the last-line treatment for Ulcerative Colitis?

Surgery

Which of the following is a common symptom of celiac disease?

Diarrhea

What is the gold standard screening method for colon cancer?

Colonoscopy

What is the most common cause of upper gastrointestinal bleeding (UGIB)?

Peptic ulcer disease

What is the recommended treatment for acute alcoholic liver disease?

Supportive care

Which hepatitis virus has a vaccine available?

All of the above

What is the most common risk factor for hepatocellular carcinoma?

Hepatitis C

Which of the following is a symptom of Crohn's Disease in the small bowel?

Non-bloody diarrhea

Which of the following is a characteristic of transmural inflammation in Crohn's Disease?

Inflammation involving the entire thickness of the colon wall

Which of the following is a consequence of Crohn's Disease?

Abscess, fistula, and stricture

Which of the following is a characteristic of ulcerative colitis?

Skip lesions in the colon

Which of the following is a diagnostic test for Crohn's Disease?

Colonoscopy and biopsy

Which of the following liver function tests is specific to the liver?

ALT

Which one of the following is a characteristic of chronic pancreatitis?

Steatorrhea and digestive discomfort

Which one of the following is a symptom of cholestasis?

Jaundice and itching

Which one of the following is a complication of acute cholangitis?

Hypotension and confusion

Which one of the following is a characteristic of primary sclerosing cholangitis?

Destruction/fibrosis of intra/extrahepatic ducts

Which one of the following is a characteristic of non-alcoholic steatohepatitis?

Inflammation + fat, asymptomatic a/w metabolic syndrome

Which one of the following is a characteristic of diverticulitis?

Inflammation/infection of diverticula

Which of the following is a risk factor for acquiring pylori infection?

Living in a crowded environment

Which of the following is a diagnostic test for pylori infection?

Urea breath test

Which therapy is used less now for pylori infection due to increased resistance?

Clarithromycin-based Triple Therapy

Which of the following is a potential sequela of pylori infection?

Gastric adenocarcinoma

Which of the following is a leading cause of nosocomial diarrhea with high mortality in the elderly?

C. diff infection

Which of the following is a lifestyle factor associated with constipation?

Low oral intake

Which of the following is a potential extraintestinal manifestation (EIM) of Crohn's Disease?

Arthritis

Which of the following liver function tests is elevated in biliary tract obstruction or alcohol consumption?

GGT

Which of the following is a potential complication of acute pancreatitis?

Cholecystitis

Which of the following liver function tests is specific to the liver?

ALT

Which of the following is a potential risk factor for developing Crohn's Disease?

Smoking

Which of the following is a characteristic of ulcerative colitis?

Bloody diarrhea

Which one of the following is a characteristic of acute Hepatitis A?

Transmission through contaminated food/water

Which one of the following is a diagnostic test for Hepatitis B?

Positive HBsAg

Which one of the following is a potential consequence of chronic Hepatitis C infection?

Risk for cirrhosis or hepatocellular carcinoma

Which one of the following is a risk factor for developing hepatocellular carcinoma?

Cirrhosis

Which one of the following is the most common cause of lower gastrointestinal bleeding (LGIB)?

Diverticulosis

Which one of the following is a characteristic of occult gastrointestinal bleeding?

Often slow and morbid

Which one of the following is a characteristic of Crohn's Disease?

Can involve the colon more proximally

Which one of the following is a potential extraintestinal manifestation (EIM) of Crohn's Disease?

All of the above

What is the first-line treatment for Crohn's Disease?

Immunomodulators

Which one of the following is a potential extraintestinal manifestation (EIM) of Ulcerative Colitis?

Swelling of eyes

What is the last-line treatment for Crohn's Disease?

Biologics/JAK

What is the age range for the bimodal peak of Crohn's Disease?

20s-30s

Which of the following is a risk factor for acquiring pylori infection?

Having a large number of siblings

Which of the following is a characteristic of chronic constipation?

Response to fiber and laxative

Which of the following is a common cause of acute diarrhea?

Lactose intolerance

Which of the following is a potential consequence of chronic constipation?

Diverticula formation

Which of the following is a diagnostic test for Clostridium difficile infection?

Toxin A&B EIA

Which of the following is a potential extraintestinal manifestation of Ulcerative Colitis?

Gastric MALT lymphoma

Which of the following is a potential complication of acute pancreatitis?

Multi-organ failure

Which of the following is a symptom of chronic pancreatitis?

Pancreatic hemorrhage

Which of the following is a symptom of cholestasis?

Fatigue

Which of the following is a characteristic of primary sclerosing cholangitis?

Associated with ulcerative colitis

Which of the following is a characteristic of fatty liver disease?

Associated with metabolic syndrome

Which of the following is a characteristic of diverticulitis?

Inflammation of diverticula

Which one of the following is a defining feature of Ulcerative Colitis?

Involves the colon only

Which one of the following is a characteristic of Ulcerative Colitis?

Inflammation of mucosa layer only

Which one of the following is a symptom of Ulcerative Colitis?

Bloody diarrhea

Which one of the following is a diagnostic test for Ulcerative Colitis?

Colonoscopy & biopsy

Which one of the following is a first-line treatment for Ulcerative Colitis?

5-ASA

Which one of the following is an extraintestinal manifestation (EIM) of Ulcerative Colitis?

Swelling of eyes

Which one of the following is a characteristic of Crohn's Disease?

Results in transmural inflammation

Which one of the following is a symptom of Crohn's Disease?

Episodic abdominal pain

Which one of the following liver function tests is elevated in biliary tract obstruction or alcohol consumption?

GGT

Which one of the following is a potential cause of acute pancreatitis?

All of the above

Which one of the following is a diagnostic test for acute pancreatitis?

Lipase or amylase > 3 times normal

Which one of the following liver function tests is elevated in hepatocellular injury?

ALT

Which one of the following is a potential complication of acute pancreatitis?

Multi-organ failure

Which one of the following is a symptom of chronic pancreatitis?

Steatorrhea

Which one of the following is a potential consequence of cholestasis?

Malabsorption

Which one of the following is a characteristic of primary sclerosing cholangitis?

Destruction of intrahepatic bile ducts

Which one of the following is a characteristic of non-alcoholic steatohepatitis (NASH)?

Inflammation + fat in liver

Which one of the following is a characteristic of diverticulitis?

Inflammation/infection of diverticula

Which of the following is the most common cause of upper gastrointestinal bleeding (UGIB)?

Peptic ulcer disease

Which of the following is the gold standard for screening colon cancer?

Colonoscopy

Which of the following is a potential transmission route for Hepatitis B?

All of the above

Which of the following is a potential consequence of chronic Hepatitis C infection?

All of the above

Which of the following is a potential symptom of alcoholic liver disease?

All of the above

Which of the following is a potential diagnostic test for celiac disease?

All of the above

Which of the following is a risk factor for acquiring pylori infection?

Living in a rural area

Which of the following is a potential extraintestinal manifestation of Crohn's Disease?

MALT lymphoma

Which of the following is a characteristic of primary constipation?

Slow transit with coordinated colonic motility

Which of the following is a potential complication of chronic pancreatitis?

Change in stool caliber

Which of the following is a characteristic of osmotic diarrhea?

Decreased absorption of water and electrolytes

Which of the following is a potential consequence of secondary constipation?

Urinary incontinence

Which one of the following is a defining feature of Crohn's Disease?

Relapsing & remitting episodes of inflammation

What is a potential consequence of chronic constipation?

Diverticulitis

Which one of the following is a diagnostic test for Crohn's Disease?

Colonoscopy & biopsy

Which of the following is a potential risk factor for developing colon cancer?

Diverticulosis

Which of the following is the gold standard for screening colon cancer?

Colonoscopy

Which of the following is the most common cause of upper gastrointestinal bleeding (UGIB)?

Peptic ulcer disease

Which of the following is a potential consequence of chronic Hepatitis C infection?

Cirrhosis

Which one of the following is a potential consequence of Crohn's Disease?

Abscess

Which one of the following is a symptom of Crohn's Disease?

Non-bloody diarrhea

Which one of the following liver function tests is elevated in biliary tract obstruction?

Alkaline phosphatase (Alk phos)

Which one of the following is a risk factor for developing chronic pancreatitis?

Alcohol use

Which of the following is a risk factor for acquiring H. pylori infection?

Living in a crowded environment

What is the recommended diagnostic test for H. pylori infection?

Urea breath test

Which of the following is a potential sequela of H. pylori infection?

Gastric adenocarcinoma

Which of the following is the leading cause of nosocomial diarrhea?

C. difficile infection

Which one of the following is a potential symptom of cholelithiasis?

Fatigue

Which one of the following is a potential consequence of primary biliary cholangitis?

Malabsorption

Which one of the following is a potential cause of acute cholangitis?

Stone in common bile or pancreatic duct

Which one of the following is a potential consequence of alcoholic liver disease?

Biliary cirrhosis

Which of the following is a defining feature of Ulcerative Colitis?

Involves the colon only

What is the first-line treatment for Ulcerative Colitis?

5-ASA

Which of the following is an extraintestinal manifestation (EIM) of Ulcerative Colitis?

Swelling of skin (Erythema nodosum)

Which of the following is a risk factor for developing chronic Helicobacter pylori infection?

Living in a crowded living environment

Which of the following is a potential complication of chronic constipation?

Diverticula formation

Which of the following is a potential cause of secretory diarrhea?

Inflammatory bowel disease

Which of the following is a characteristic of chronic diarrhea?

Increased stool consistency

Which of the following is a potential symptom of celiac disease?

Chronic fatigue

Which of the following is a risk factor for developing colon cancer?

Ulcerative colitis

Which of the following is the gold standard for diagnosing celiac disease?

Duodenal biopsy

Which of the following is a potential cause of upper gastrointestinal bleeding (UGIB)?

Peptic ulcer disease

Which one of the following is a potential symptom of Crohn's Disease?

Non-bloody diarrhea

Which one of the following liver function tests is elevated in biliary tract obstruction?

Alkaline phosphatase (Alk phos)

Which one of the following is a potential consequence of chronic Hepatitis C infection?

Liver cirrhosis

Which one of the following is a characteristic of non-alcoholic steatohepatitis?

Presence of liver inflammation and fibrosis

Which one of the following is a potential complication of acute cholangitis?

Hepatic abscess

Which one of the following is a symptom of cholecystitis?

RUQ pain

Which one of the following is a potential cause of chronic pancreatitis?

Alcohol intake

Which one of the following is a characteristic of primary sclerosing cholangitis?

Associated with ulcerative colitis

Study Notes

Gastrointestinal Conditions and Liver Function Tests

  • Ulcerative colitis and Crohn's disease are both immune-mediated conditions characterized by relapsing and remitting episodes of inflammation.
  • Ulcerative colitis specifically involves the colon and always involves the rectum, while Crohn's disease can affect any part of the GI tract.
  • Ulcerative colitis is characterized by inflammation of the mucosa layer of the colon, while Crohn's disease involves the entire thickness of the colon wall.
  • Symptoms of ulcerative colitis include bloody diarrhea, abdominal pain, fatigue, anemia, and joint swelling, among others.
  • Diagnosis of ulcerative colitis and Crohn's disease is done through colonoscopy and biopsy.
  • Treatment for both conditions includes medications such as 5-ASA, immunomodulators, steroids, and biologics, with surgery being a last-line option.
  • Irritable bowel syndrome (IBS) is characterized by altered GI motility and visceral hypersensitivity, and is diagnosed based on recurrent abdominal pain without other causes.
  • Treatment for IBS mainly involves vigorous exercise, while diet changes are not considered helpful.
  • Liver function tests such as ALT, AST, Alk phos, GGT, bilirubin, PT, and INR are used to assess liver function and injury.
  • Acute hepatocellular damage is indicated by elevated AST and ALT levels, while biliary obstruction/cholestasis is indicated by elevated Alk phos and GGT levels.
  • Gilbert's syndrome is a benign condition characterized by mildly elevated bilirubin levels.
  • Conditions such as acute pancreatitis, cholestasis, cholelithiasis, and cholecystitis have specific diagnostic criteria and treatment approaches.

Test your knowledge on the complications and symptoms of pancreatitis, including inflammation, necrosis, and pancreatic pseudocysts. Learn about treatment options such as cholecystectomy, stone removal by ERCP, apheresis, and insulin drip for elevated triglyceride levels. Don't forget to review the specific characteristics of chronic pancreatitis in alcoholic patients.

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