Pancreas and Gallbladder Quiz

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Questions and Answers

What is the most common type of gallstone?

  • Bilirubin salts
  • Phosphate stones
  • Calcium stones
  • Cholesterol stones (correct)

What is the term for an outpouching or sinus of the mucosa in the gall bladder?

  • Zenker's diverticulum
  • Rokitansky-Aschoff sinus (correct)
  • Barrett's esophagus
  • Mallory-Weiss tear

What is the term for a calcified gall bladder wall?

  • Cholangitis
  • Gallstone
  • Porcelain gall bladder (correct)
  • Cholecystitis

Which of the following is NOT a common cause of acute pancreatitis?

<p>Diabetes (A)</p> Signup and view all the answers

What is the most common type of pancreatic cancer?

<p>Adenocarcinoma (B)</p> Signup and view all the answers

What is the function of the pancreas?

<p>Secretes digestive enzymes (C)</p> Signup and view all the answers

Which of the following is a congenital anomaly of the pancreas?

<p>Pancreas divisum (B)</p> Signup and view all the answers

Which of the following is a proenzyme secreted by the pancreas?

<p>Trypsinogen (A)</p> Signup and view all the answers

Which of the following can cause acute pancreatitis?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary mechanism behind acute pancreatitis?

<p>Autodigestion of the pancreas by its own enzymes (B)</p> Signup and view all the answers

Which laboratory findings are typically elevated in a patient with acute pancreatitis?

<p>Amylase and lipase levels (C)</p> Signup and view all the answers

What is a pancreatic pseudocyst?

<p>A collection of fluid that forms after pancreatic inflammation (C)</p> Signup and view all the answers

Which of the following is NOT a common factor associated with chronic pancreatitis?

<p>Hypocalcemia (A)</p> Signup and view all the answers

What is the key morphological feature of chronic pancreatitis?

<p>Pancreatic atrophy with extensive fibrosis (C)</p> Signup and view all the answers

What is the primary cause of chronic pancreatitis?

<p>Repeated bouts of acute pancreatitis and ductal obstruction (B)</p> Signup and view all the answers

Chronic pancreatitis can lead to the loss of which cells in the pancreas?

<p>Both acinar and islet cells (C)</p> Signup and view all the answers

What demographic is most commonly affected by pancreatic conditions?

<p>Middle aged males, particularly alcoholics (B)</p> Signup and view all the answers

What is a common early clinical feature of carcinoma of the pancreas?

<p>Obstructive jaundice (B)</p> Signup and view all the answers

Which type of tumor accounts for the majority of pancreatic tumors?

<p>Adenocarcinomas (A)</p> Signup and view all the answers

What is a significant risk factor for developing pancreatic carcinoma?

<p>Smoking (B)</p> Signup and view all the answers

What is a common symptom of pancreatic tumors as they progress?

<p>Migratory thrombophlebitis (C)</p> Signup and view all the answers

Which pancreatic tumor is most frequently benign and cystic?

<p>Serous cystadenoma (B)</p> Signup and view all the answers

What is the expected clinical presentation of pancreatic carcinoma in its later stages?

<p>Pain in the abdomen and back (D)</p> Signup and view all the answers

Which of the following mutations is most commonly associated with pancreatic carcinoma?

<p>K-ras mutation (D)</p> Signup and view all the answers

Flashcards

Acute Pancreatitis

Sudden inflammation of the pancreas, causing autodigestion by enzymes.

Pathogenesis of Acute Pancreatitis

Due to autodigestion from activated trypsinogen and enzyme leakage.

Clinical Features

Includes abdominal pain, elevated amylase/lipase, and secondary effects like hypocalcemia.

Pancreatic Pseudocyst

Localized collection of pancreatic secretions from damaged ducts, often post-inflammation.

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Chronic Pancreatitis

Long-term inflammation resulting in loss of pancreatic tissue and fibrosis.

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Risk Factors for Chronic Pancreatitis

Factors like alcoholism and hyperlipoproteinaemia contribute to chronic cases.

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Morphology of Chronic Pancreatitis

Characterized by fibrosis, acinar loss, and duct obstruction.

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Sequelae of Acute Pancreatitis

Possible outcomes include sterile abscesses, pseudocysts, and duodenal obstruction.

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Cholelithiasis

The presence of stones in the gall bladder, primarily cholesterol or pigment stones.

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Acute Cholecystitis

Inflammation of the gall bladder, often due to stone obstruction, causing bile stasis and possible infection.

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Chronic Cholecystitis

Long-term inflammation of the gall bladder, characterized by a thickened wall and possible gallstones.

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Rokitansky-Aschoff Sinuses

Outpouchings or sinuses in the mucosa of a chronically inflamed gall bladder.

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Gall Bladder Carcinoma

A rare cancer of the gall bladder, often linked to gallstones, commonly found in women.

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Exocrine Pancreas Functions

Secretes 2-2.5 liters/day of bicarbonate-rich fluid with digestive enzymes.

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Cystic Fibrosis

A genetic disorder affecting the pancreas, leading to thick secretions and obstructive problems.

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Pancreatic Carcinoma

A malignant tumor of the pancreas, usually adenocarcinoma, often asymptomatic until advanced.

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Tumor Location in Pancreas

Most pancreatic tumors arise in the head (60%), followed by body (5%) and tail (5%).

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K-ras Mutation

A genetic mutation common in pancreatic cancer, present in approximately 90% of cases.

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Symptoms of Pancreatic Cancer

Common symptoms include abdominal pain, jaundice, weight loss, and malaise.

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Risk Factors for Pancreatic Cancer

Key risk factors include smoking, alcoholism, high-fat diet, and chronic pancreatitis.

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Tumor Markers

CEA and CA19-9 are commonly used tumor markers but are often unreliable for pancreatic cancer.

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