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Questions and Answers
In which laminae of the dorsal horn do nociceptive axons synapse with second order neurons?
In which laminae of the dorsal horn do nociceptive axons synapse with second order neurons?
Which neurotransmitter is released by nociceptive axons for moderate pain?
Which neurotransmitter is released by nociceptive axons for moderate pain?
Which neurotransmitters are released by nociceptive axons during stronger pain?
Which neurotransmitters are released by nociceptive axons during stronger pain?
What type of action is associated with the release of glutamate in the context of nociceptive transmission?
What type of action is associated with the release of glutamate in the context of nociceptive transmission?
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Which pair of substances are released by local inhibitory interneurons in the dorsal horn?
Which pair of substances are released by local inhibitory interneurons in the dorsal horn?
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What is the function of substance P in the dorsal horn?
What is the function of substance P in the dorsal horn?
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What is the primary function of local inhibitory interneurons in the dorsal horn?
What is the primary function of local inhibitory interneurons in the dorsal horn?
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Which lamina of the dorsal horn receives input from nociceptive axons?
Which lamina of the dorsal horn receives input from nociceptive axons?
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What is the characteristic of glutamate release in moderate pain transmission?
What is the characteristic of glutamate release in moderate pain transmission?
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What is released by nociceptive axons in addition to glutamate during stronger pain?
What is released by nociceptive axons in addition to glutamate during stronger pain?
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Study Notes
Nociceptive Axons and Synapse
- Nociceptive axons synapse with second-order neurons in the spinal cord, specifically in lamina I, II, and V of the dorsal horn.
Pain Transmission
- Moderate pain: Nociceptive axons release glutamate, which acts fast.
- Stronger pain: Nociceptive axons release glutamate, substance P, and ATP, which have slower and sustained actions.
Local Inhibitory Interneurons
- Release GABA and glycine.
Nociceptive Axons and Synapse
- Nociceptive axons synapse with second-order neurons in the spinal cord, specifically in lamina I, II, and V of the dorsal horn.
Pain Transmission
- Moderate pain: Nociceptive axons release glutamate, which acts fast.
- Stronger pain: Nociceptive axons release glutamate, substance P, and ATP, which have slower and sustained actions.
Local Inhibitory Interneurons
- Release GABA and glycine.
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Description
This quiz covers the transmission of pain signals in the spinal cord, including the role of nociceptive axons, second-order neurons, and inhibitory interneurons.
