Sterile Compounding and Aseptic Techniques - CH 10

pH = a measure of the acidity or alkalinity of a solution hypertonic = when a solution has a greater osmolarity than that of blood hypotonic = when a solution has a less osmolarity than that of blood isotonic = when a solution has an osmolarity equivalent to that of blood

osmotic pressure = a characteristic of a solution determined by the number of dissolved particles in it pyrogens = chemicals produced by microorganisms that can cause pyretic reactions (fever) in patients additive = a drug that is added to a parenteral solution admixture = the resulting solution when a drug is added to a parenteral solution

diluent = a solvent that dissolves a lyophilized powder or dilutes a solution lyophilized = freeze-dried ready to mix = a specially designed minibag by which a drug is put into the SVP just prior to administration dialysis = movement of particles in a solution through permeable membranes

<p>irrigation solution = a large volume splash solution used during a surgical or urologic procedures to bathe and moisten body tissues osmosis = the action in which a drug in a higher concentration solution passes through a permeable membrane to a lower concentration solution peritoneal dialysis solution = a solution placed in and emptied from the peritoneal cavity to remove toxic substances total nutrient admixture (TNA) solution = a TPN solution that contains intravenous fat emulsion</p> Signup and view all the answers

<p>total parenteral nutrition (TPN) solution = a complex solution with two base solutions (amino acids and dextrose) and additional micronutrients flashball = a flexible rubber bulb near the needle adapter used to determine if the needle is properly placed in the vein flow rate = the rate at which solution is administered to the patient heparin lock = an administration device used when a primary LVP solution is not available</p> Signup and view all the answers

<p>piggyback = small volume solutions connected to an LVP HEPA filter = a high efficiency particulate air filter horizontal airflow workstation = a laminar flow workstation with horizontal airflow across the work area laminar flow = continuous movement at a uniform rate in one direction</p> Signup and view all the answers

<p>Primary and Secondary Engineering Controls (PECs, SECs) = a device or room that provides appropriate air quality when compounding CSPs vertical airflow workstation = a laminar flow workstation with vertical airflow across the work area zone of turbulence = an area of blocked airflow in a laminar airflow workstation coring = when a needle damages the rubber closure of a parenteral container causing fragments of the closure to fall into the container and contaminate its contents</p> Signup and view all the answers

<p>ampules = sealed glass containers with an elongated neck that must be snapped off before use bevel = an angled surface at the tip of a needle gauge = a measurement with needles; the higher the gauge, the smaller the lumen hub = the part of the needle that attaches to the syringe</p> Signup and view all the answers

<p>lumen = the hollow enter of a needle shaft = the stem of the needle that provides the overall length of the needle Slip Tip, Luer-Lok, eccentric, oral = different types of syringe tips sharps = needles, jagged glass or metal objects, or any items that might puncture or cut the skin</p> Signup and view all the answers

<p>depth filter = a filter that can filter solutions being drawn into or expelled from a syringe, but not both ways in the same procedure final filter = a filter placed immediately before a solution enters a patient's vein membrane filter = a filter that filters solution as the solution is expelled from the syringe nonviable particles = environmental or personnel particles that do not have microbial contamination associated with them</p> Signup and view all the answers

<p>viable particles = particles that have microbial contamination associated with them anhydrous = without water molecules equivalent weight = a drug's molecular weight divided by its valence; a common measure of electrolyte concentration ions = molecular particles that carry electric charges</p> Signup and view all the answers

<p>valence = the number of positive or negative charges on an ion waters of hydration = water molecules that attach to drug molecules a = b c = d</p> Signup and view all the answers

<p>It is free from bacteria</p> Signup and view all the answers

<p>The United States Pharmacopeia</p> Signup and view all the answers

<p>Multivitamins, two 5 mL vials</p> Signup and view all the answers

<p>volume control chamber</p> Signup and view all the answers

<p>ISO Class 5 laminar airflow workstation</p> Signup and view all the answers

<p>dust</p> Signup and view all the answers

<p>help withdraw the solution by pressurizing the vial</p> Signup and view all the answers

<p>reconstituting the lyophilized drug in the vial and adding it to the LVP</p> Signup and view all the answers

<p>only prescored ampules can be used</p> Signup and view all the answers

<p>can be prevented by initially angling the needle and moving upright when entering the vial</p> Signup and view all the answers

<p>fill the syringe, hub, and needle with liquid and remove all air bubbles.</p> Signup and view all the answers

<p>withdrawing solution from an ampule</p> Signup and view all the answers

<p>particle contamination, precipitation</p> Signup and view all the answers

<p>90%</p> Signup and view all the answers

<p>Percentage weight per volume</p> Signup and view all the answers

<p>the LAFW is only cleaned at the beginning and end of a shift</p> Signup and view all the answers

<p>immediate use</p> Signup and view all the answers

<p>an agent that removes or destroys vegetative forms of microorganisms on a surface</p> Signup and view all the answers

<p>the time of day when the preparation is prepared</p> Signup and view all the answers

<p>no work should be done within 6 inches of the front of the workstation</p> Signup and view all the answers

<p>all of the above</p> Signup and view all the answers

<p>some medications cause pain at the injection site</p> Signup and view all the answers

<p>jewelry on the hands or wrists</p> Signup and view all the answers

<p>all of the above</p> Signup and view all the answers

<p>Put on shoe covers and hair bonnet</p> Signup and view all the answers

<p>microorganisms</p> Signup and view all the answers

<p>hypotonic</p> Signup and view all the answers

<p>25-100 mL</p> Signup and view all the answers

<p>additive; admixture</p> Signup and view all the answers

<p>compounding aseptic containment isolator</p> Signup and view all the answers

<p>the hub</p> Signup and view all the answers

<p>filter needles</p> Signup and view all the answers

<p>toward the operator</p> Signup and view all the answers

<p>vertical air low down toward the work</p> Signup and view all the answers

<p>small supplies should be placed closer to the HEPA filter</p> Signup and view all the answers

<p>3/4</p> Signup and view all the answers

<p>score the neck of the ampule with a fine file</p> Signup and view all the answers

<p>0.05%</p> Signup and view all the answers

<p>110.94</p> Signup and view all the answers

<p>1</p> Signup and view all the answers

<p>37.3 g</p> Signup and view all the answers