59 Questions
Match the terms
alveolar sacs (alveoli) = the small sacs of specialized tissue that transfer oxygen out of inspired air into the blood and carbon dioxide out of the blood and into the air for exhalation aqueous = water based biocompatible = not irritating; does not promote infection or abscess buccal = pouch between the teeth and cheek in the mouth
Match the terms
buffer system = ingredients in a formulation designed to control the pH colloids = particles up to a hundred times smaller than those in suspensions that are, however, also suspended in a solution conjuctiva = the eyelid lining contraceptive = device or formulation designed to prevent pregnancy
Match terms
depot = the area in the muscle where the formulation is injected during an intramuscular injection diluent = solvent that dissolves a freeze dried powder or diluents a solution disintegration = the breaking apart of a tablet into smaller pieces dissolution = when the smaller pieces of a disintegrated tablet dissolve in solution
Match terms
emulsifier = a stabilizing agent in emulsions emulsions = mixture of two non-miscible liquids where one is dispersed throughout the other as tiny droplets hemorrhoid = painful swollen veins in the anal/rectal area, generally caused by strained bowel movements from hard stools hydrates = absorbs water
Match terms
injectability = the ease of flow when a suspension is injected into a patient intrauterine device (IUD) = an intrauterine contraceptive device that is placed in the uterus for a prolonged period of time lacrimal canaliculi = the tear ducts lacrimal gland = the gland that produces tears for the eye
Match the terms
local effect = when drug activity is at the site of administration nasal cavity = the cavity behind the nose and above the roof of the mouth that filters air and moves mucus and inhaled contaminants outward and away from the lungs nasal inhaler = a device that contains a drug that is vaporized by inhalation nasal mucosa = the cellular lining of the nose
Match terms
necrosis = increase in cell death ophthalmic = related to the eye percutaneous absorption = the absorption of drugs through the skin, often for systemic effect pH = measures the acidity or alkalinity of a substance
Match the terms
Solution = a clear liquid made up of one or more substances dissolved in a solvent sterile = a condition that is free of all microorganisms stratum corneum = the outermost cell layer of the epidermis sublingual = under the tongue
Terms
syringeability = the ease with which a suspension can be drawn from a container into a syringe systemic effect = when a drug is introduced into the circulatory system and carried to the site of activity viscosity = a measure of a liquid's thickness or resistance to flow water soluble = able to dissolve in water
Wheal is a raised, blister-like area on the skin caused by intradermal injection
True
A parenteral route of administration means that the route of administration is
next to or beside the enteral tract
A dissolution step would not be necessary for drug absorption from a/an
oral syrup
Modified release tablets might be called
all of the above
Nonaqueous solutions often contain glycerin, alcohol, and
propylene glycol
An oral liquid formulation in which one non-miscible liquid is dispersed throughout another in the form of small droplets is called
an emulsion
A gel is characterized by
a 3D network of particles
Which will not be caused by particulate material in an intravenous injection?
air emboli
A raised, blister-like area on the skin caused from an intradermal injection is called a
wheal
The average tear volume in the eye in 10 microliter. The average drop size from an eye dropper is ______ microliter.
50
Do not use an ophthalmic solution if it
all of the above
What percent of the administered ophthalmic solution is delivered to the eye?
20 %
When administering a nasal spray
breathe through the nostril while spraying the solution
The role of an inhalation spacer is to
allow the patient to separate actuation from inhalation by seconds
Dermal formulations can deliver about _____ mg/hr of active drug
2
The primary reason to use a vaginal applicator is to
place the formulation high in the vaginal tract
Which is not a true statement about vaginal administrations and or formulation?
it cannot provide long term absorption
Which statement is false?
Rectal suppositories are intended to spread around the anal opening
Which of the following absorption rate rankings (from fastest to slowest) is correct when considering IM administration?
aqueous solution > oleaginous solutions > colloids > suspensions
When administering ophthalmic drops, why is instilling two drops at a time not recommended?
The second drop will be lost in spillage
Which statement is not a reason to use parenteral routes of administration
a drug is rapidly absorbed when orally administered
In subcutaneous administration
the site of injection is often rotated
Tablets generally contain ingredients in addition to the active drug. Which statement is not true?
they increase the dissolution time of the active drug
What is a major disadvantage of using a solution or tincture for dermal applications?
the formulation will not remain on the skin for an extended period of time
Which statement is not true about intranasal and inhalation administration?
subjects the active drug to degradation in the gastrointestinal tract
Some routes of administration are selected because the active drug will provide a localized effect. But often, a systemic effect is also seen. How can this happen?
The route of administration has a large blood supply and some of the active drug is absorbed into the system circulation
You have received a prescription for a sublingual tablet for risperadol, but you only have the immediate-release tablets of the same strength in the stock. You are questioning whether you can substitute the immediate release for the SL tablet. Which statement is false?
the immediate release tablet can only be swallowed
What route of administration will give the highest blood concentration in the shortest time?
intravenous
Buccal administration is a parenteral route of administration
False
Oral administration is the most frequently used route of administration
True
With oral formulations, drugs administered by solid dosage forms generally reach the systemic circulation faster than liquid dosage forms
False
The stomach has a pH of around 1 or 2
True
In an emulsion, if the oleaginous component is present as droplets, the emulsions is called water-in-oil
False
Phlebitis can be a complication of intravenous adminsitration
True
the needle length for subcutaneous injection is generally 3/8 to 1 inch
True
It takes about 20 seconds for an intravenously administered drug to circulate throughout the body
True
Toxic shock syndrome is a disease caused by a bacterial infection
True
_____ tablets are placed un the tongue
sublingual
The pH of the stomach is around
1-2
_______ injections are administered directly into veins
intravenous
Inflammation of a vein us also known as ______ and can be a complication associated with intravenous administration
phlebitis
The gradual intravenous injection of a volume of fluid into a patient is called
infusion
The most common kind of oral solution
capsules
______ contain (s) the active drug in a small powder paper or foil envelope
bulk powder
Most frequently used as flavoring agents
spirits or essences
A device that goes between an aerosol's mouthpiece and the patient's mouth is a/an
spacer
_________ absorption is the absorption of drugs through the skin, often for systemic effect
intravenous
A local effect achieved by rectal administration
anti-infective
The most common injection route for insulin is
subcutaneous
Devices that have special metering valves to administer drugs by inhalation
MDI aerosols
Test your knowledge by matching the given terms to their corresponding definitions or descriptions. This quiz is designed to assess your understanding of various terms within a specific subject or field.
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