Oxygen Transfer Process in Liquid Media
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Questions and Answers

What does the term xQO2 represent in the oxygen transfer model equation?

  • The initial concentration of biomass in the system
  • Concentration of dissolved oxygen in the water
  • Total biomass concentration in the system
  • Rate of oxygen consumption per gram of biomass per hour (correct)
  • In the equation OTR = dCL / dt = kLa(C*-CL) – xQO2, what does the variable kLa signify?

  • Coefficient of mass transfer for oxygen (correct)
  • Concentration of inhibitors in the reaction
  • Rate of product formation in the process
  • Rate of biomass growth per hour
  • Which formula accurately represents the relationship between the change in concentration of dissolved oxygen and time, considering the oxygen transfer model?

  • dCL/dt = kLa(C* - CL) (correct)
  • CL = kLa(dC/dt) + C0
  • C* = dCL/dt + kLa(CL)
  • CL = C* + kLa(dt)
  • What is the significance of the term (C* - CL) in the context of the oxygen transfer model?

    <p>It indicates the oxygen deficit in the system.</p> Signup and view all the answers

    What does the slope of the line AB in the dynamic gassing out method typically represent?

    <p>The specific respiration rate for oxygen consumption</p> Signup and view all the answers

    What happens to the rate of oxygen transfer if the bubble is rich in carbon dioxide?

    <p>Oxygen transfer out of the bubble will be slow or zero.</p> Signup and view all the answers

    What role does the oxygen concentration in the bubble play in the oxygen transfer process?

    <p>Higher concentrations facilitate oxygen transfer.</p> Signup and view all the answers

    Which of the following factors significantly affects the rate of diffusion of oxygen?

    <p>All of the above</p> Signup and view all the answers

    In which scenario is the contribution to oxygen transfer resistance negligible?

    <p>When individual cells are dispersed in the fluid.</p> Signup and view all the answers

    Which condition among these implies significant oxygen transfer resistance?

    <p>Stagnant media surrounding large cell clumps</p> Signup and view all the answers

    What is the main characteristic of diffusion through the bubble boundary layer?

    <p>It is slow because the solutes must move through stagnant liquid.</p> Signup and view all the answers

    What contributes to oxygen transfer resistance during diffusion through cell intraparticle resistance?

    <p>The size of the cell clumps</p> Signup and view all the answers

    How does the transfer through the bulk liquid contribute to oxygen transfer resistance?

    <p>It contributes negligibly only in turbulent and less viscous media.</p> Signup and view all the answers

    What is the effect of stalled impeller conditions on bubble size in a liquid-gas system?

    <p>It causes the formation of large bubbles, reducing oxygen transfer efficiency.</p> Signup and view all the answers

    Which factors can significantly affect the kLa in a gas-liquid system?

    <p>Impeller diameter and stirrer speed.</p> Signup and view all the answers

    What is the relationship between the inlet flow rate ratio QL/QG and gas holdup?

    <p>Higher QL/QG ratios increase gas holdup significantly.</p> Signup and view all the answers

    Which aspect does NOT directly influence the oxygen transfer rate in a gas-liquid system?

    <p>Type of gas used.</p> Signup and view all the answers

    Why is increasing stirrer speed beneficial for oxygen transfer rates?

    <p>It decreases the diameter of bubbles formed.</p> Signup and view all the answers

    What characteristics of a sparger can significantly influence kLa values?

    <p>Bubble size, gas velocity, and flow rates.</p> Signup and view all the answers

    How does the number of impellers on a stirrer shaft affect kLa?

    <p>More impellers can lead to lesser kLa due to poor mixing.</p> Signup and view all the answers

    What is the main consequence of a flooded impeller scenario in liquid-gas systems?

    <p>Large bubbles that reduce oxygen transfer efficiency.</p> Signup and view all the answers

    What does the two-film theory primarily suggest about mass transfer?

    <p>It models the resistance to diffusion as equivalent to stagnant films.</p> Signup and view all the answers

    In penetration theory, how does mass transfer occur?

    <p>By turbulent eddies remaining at the interface for an exposure time.</p> Signup and view all the answers

    What is the relationship between mass-transfer coefficient and molecular diffusivity in penetration theory?

    <p>They are directly proportional.</p> Signup and view all the answers

    According to surface renewal theory, what does the surface age distribution function represent?

    <p>The varying ages of surface elements over time.</p> Signup and view all the answers

    Why is oxygen transfer significant in bioprocess engineering?

    <p>It is involved in the production of biochemicals.</p> Signup and view all the answers

    What does the term 'exposure time' refer to in penetration theory?

    <p>The duration solutes spend at the interface.</p> Signup and view all the answers

    How does the two-film theory differ from the penetration theory?

    <p>The two-film theory does not consider turbulent eddies.</p> Signup and view all the answers

    Which statement best describes the concept of molecular diffusion in the context of mass transfer?

    <p>It involves the random movement of molecules from high to low concentration.</p> Signup and view all the answers

    What does Co represent in the given equations?

    <p>Oxygen concentration</p> Signup and view all the answers

    Which equation represents the Oxygen Uptake Rate (OUR)?

    <p>OUR = $ rac{1 imes u_{max} C_o}{Y_o K_o + C_o}$</p> Signup and view all the answers

    Which of the following statements is true regarding the relationship between OTR and OUR at steady-state?

    <p>OTR is equal to OUR</p> Signup and view all the answers

    What does $ u_{max}$ signify in the equations?

    <p>Maximum specific growth rate</p> Signup and view all the answers

    In the equation $dC_o/dt$, what does this represent in the context of oxygen concentration?

    <p>Rate of change of oxygen concentration</p> Signup and view all the answers

    Which variable does $Y_o$ represent in the equations?

    <p>Biomass yield from oxygen</p> Signup and view all the answers

    What is the significance of the Monod constant $K_o$?

    <p>It indicates the concentration of oxygen required for half-maximal growth</p> Signup and view all the answers

    What does the equation $dC_o/dt = k_L a (C_o^* - C_o) - X$ describe?

    <p>Dynamic balance of oxygen in the reactor</p> Signup and view all the answers

    Study Notes

    Oxygen Transfer Model Equation

    • xQO2 represents the rate of oxygen consumption by microorganisms in the system.
    • kLa represents the volumetric mass transfer coefficient, quantifying the efficiency of oxygen transfer between the gas phase and the liquid phase.
    • dCL / dt = kLa(C-CL) – xQO2* accurately represents the change of dissolved oxygen concentration over time.
    • (C - CL)* signifies the driving force for oxygen transfer, representing the difference between the oxygen saturation concentration (C*) and the actual dissolved oxygen concentration (CL).

    Dynamic Gassing Out Method

    • The slope of the line AB in the dynamic gassing out method typically represents the kLa value.

    Factors Affecting Oxygen Transfer

    • CO2 in bubbles decreases oxygen transfer rate.
    • Oxygen concentration in the bubble is directly proportional to the oxygen transfer rate.
    • Factors affecting the rate of oxygen diffusion include temperature, pressure, and the nature of the membrane.
    • Contribution to oxygen transfer resistance can be neglected in the bulk liquid if there's a high level of agitation.
    • Significant oxygen transfer resistance is evident when agitation is low or the liquid viscosity is high.
    • Diffusion through the bubble boundary layer is characterized by a rapid decrease in concentration due to the large surface area of the bubble.
    • Cell intraparticle resistance is influenced by the presence of cell walls and internal structures.
    • Transfer through the bulk liquid contributes resistance to oxygen transfer due to factors like convection currents.
    • Stalled impeller conditions lead to larger bubbles in a liquid-gas system.

    kLa and Gas-Liquid Systems

    • Factors impacting kLa in a gas-liquid system include agitation, sparger design, and liquid properties.
    • The inlet flow rate ratio (QL/QG) is directly proportional to the gas holdup.
    • Factors that impact oxygen transfer rate in a gas-liquid system include kLa, (C*-CL), and xQO2.
    • Increased stirrer speed improves oxygen transfer rate by creating smaller bubbles and increasing gas holdup.
    • Sparger characteristics like orifice size, shape, and material significantly influence kLa.
    • The number of impellers on a stirrer shaft impacts kLa, with more impellers potentially increasing kLa due to better mixing.
    • Flooded impellers in liquid-gas systems lead to decreased oxygen transfer due to reduced gas holdup and inefficient mixing.

    Oxygen Transfer Theories

    • Two-film theory suggests that mass transfer occurs through two stagnant films at the gas-liquid interface.
    • Penetration theory states that mass transfer occurs by penetration of the gas into the liquid, creating a concentration gradient that drives diffusion.
    • Mass transfer coefficient in penetration theory is directly proportional to the square root of the molecular diffusivity.
    • Surface age distribution function in surface renewal theory represents the distribution of time that a surface element has been exposed to the bulk fluid.

    Oxygen Transfer and Bioprocessing Engineering

    • Oxygen transfer is vital in bioprocessing because it provides the oxygen needed for microbial growth and metabolism.
    • Exposure time in penetration theory represents the duration a fresh surface element is exposed to the bulk liquid.
    • Two-film and penetration theories are distinct in their descriptions of the mass transfer mechanism, but both focus on film resistance and concentration gradients.
    • Molecular diffusion in mass transfer involves the movement of molecules from areas of higher concentration to lower concentration.
    • Co in the equations represents the oxygen concentration.

    Oxygen Uptake Rate (OUR)

    • OUR is represented by the equation X = μ (C_o) X
    • At steady-state, OTR = OUR.
    • $u_{max}$ signifies the maximum specific growth rate of microorganisms.
    • $dC_o/dt$ represents the rate of change in oxygen concentration over time.
    • $Y_o$ represents the yield of biomass per unit of oxygen consumed.
    • Monod constant $K_o$ represents the oxygen concentration at which the specific growth rate is half its maximum value.
    • $dC_o/dt = k_L a (C_o^ - C_o) - X$* describes the balance between oxygen transfer rate and oxygen uptake rate.

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