Podcast
Questions and Answers
What's the equation for DO2?
What's the equation for DO2?
DO2 = Cardiac Output x [(Hgb x SaO2 x 1.34) + (PaO2 x 0.003)] x 10
To understand the essence of DO2, what are the two questions we need to ask?
To understand the essence of DO2, what are the two questions we need to ask?
- How much oxygen is in the blood? 2. How fast is the oxygen being delivered to the tissues?
Remember the amount of gas dissolved in a solution follows ________ law.
Remember the amount of gas dissolved in a solution follows ________ law.
Henry's law
What is the normal DO2?
What is the normal DO2?
Signup and view all the answers
What is the normal oxygen extraction?
What is the normal oxygen extraction?
Signup and view all the answers
What is the whole body O2 extraction ratio?
What is the whole body O2 extraction ratio?
Signup and view all the answers
___________ tells us how many grams per deciliter of oxygen are contained in the blood.
___________ tells us how many grams per deciliter of oxygen are contained in the blood.
Signup and view all the answers
What is the solubility coefficient for dissolved oxygen in the blood?
What is the solubility coefficient for dissolved oxygen in the blood?
Signup and view all the answers
Myocardial function is determined by what 3 things?
Myocardial function is determined by what 3 things?
Signup and view all the answers
What does the Oxygen Carrying Capacity: CaO2 tell you, and what is the reference value?
What does the Oxygen Carrying Capacity: CaO2 tell you, and what is the reference value?
Signup and view all the answers
What does Oxygen Delivery: DO2 tell you, and what is the reference value?
What does Oxygen Delivery: DO2 tell you, and what is the reference value?
Signup and view all the answers
What does Oxygen Extraction Ratio: EO2 tell you, and what is the reference value?
What does Oxygen Extraction Ratio: EO2 tell you, and what is the reference value?
Signup and view all the answers
What does Oxygen Consumption: VO2 tell you, and what is the reference value?
What does Oxygen Consumption: VO2 tell you, and what is the reference value?
Signup and view all the answers
What does Venous Oxygen Content: CvO2 tell you, and what is the reference value?
What does Venous Oxygen Content: CvO2 tell you, and what is the reference value?
Signup and view all the answers
Study Notes
Oxygen Delivery Overview
- DO2 equation: DO2 = Cardiac Output x [(Hgb x SaO2 x 1.34) + (PaO2 x 0.003)] x 10
- Brackets signify oxygen carrying capacity (CaO2).
- The factor 10 adjusts units (Hgb in g/dL and CO in L/min).
- Example: If CO = 5 L/min and CaO2 = 20 mL/dL, then DO2 = 1,000 mL O2/min.
Key Questions About DO2
- Essential questions:
- How much oxygen is in the blood?
- How fast is the oxygen being delivered to the tissues?
Gas Dissolution Law
- The amount of gas dissolved in a solution follows Henry's law.
Normal Values
- Normal DO2: 1,000 mL/min
- Normal oxygen extraction: 250 mL/min
- Whole body O2 extraction ratio: 25%.
Oxygen Carrying Capacity
- CaO2 indicates grams of oxygen per deciliter in blood.
- Reference value for CaO2: 20 mL/dL.
Oxygen Delivery Characteristics
- DO2 measures how much O2 is carried in the blood and its delivery speed.
- Reference value for DO2: 1,000 mL/min.
Oxygen Extraction and Consumption
- EO2 reflects how much O2 is extracted by tissues.
- Whole body reference value for EO2: 25%.
- VO2 measures oxygen consumed by tissues at rest.
- Reference value for VO2: 250 mL/min.
Venous Oxygen Content
- CvO2 indicates O2 carried in venous blood.
- Reference value for CvO2: 15 mL/dL.
Myocardial Function Determinants
- Three factors influencing myocardial function:
- Preload
- Afterload
- Contractility.
Solubility of Oxygen
- The solubility coefficient for dissolved oxygen in the blood is 0.003.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Test your knowledge on oxygen delivery equations and concepts. This quiz covers key calculations and understanding of DO2, focusing on cardiac output and oxygen carrying capacity. Perfect for students in physiology or medicine.
