Environmental Path

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Questions and Answers

What is the definition of an agent being considered toxic?

  • When signs of toxicity appear in 50% of the exposed population (correct)
  • When it is ingested by at least 50% of a population
  • When it reaches the lethal dose for 50% of the population
  • When it has no observable effect on the exposed population

What does the threshold effect refer to in toxicology?

  • The cumulative amount of drug after repeated exposures
  • The maximum amount of toxin the body can tolerate without symptoms
  • The average dosage expected to produce lethality
  • The minimum dose required to observe any effect (correct)

What are common portals of entry for a toxic agent?

  • Ingestion and contact with mucous membranes
  • Absorption and inhalation
  • Ingestion and inhalation (correct)
  • Inhalation and contact with skin

Which concept is similar to TD50/LD50 in toxicology?

<p>Toxic dose (A)</p> Signup and view all the answers

What aligns with the objective of understanding etiologic agents in environmental pathology?

<p>Identifying environmental causes of tumors (B)</p> Signup and view all the answers

What is environmental disease primarily caused by?

<p>Chemical or physical agents (D)</p> Signup and view all the answers

Which of the following is a major determinant of health?

<p>Food and water quality (D)</p> Signup and view all the answers

What percentage of reported occupational diseases were due to repeated trauma in the US?

<p>64% (C)</p> Signup and view all the answers

Which occupational disease had the lowest reported number in the US?

<p>Poisoning (D)</p> Signup and view all the answers

Which type of injury is classified under injury by physical agent?

<p>Electrical injury (B)</p> Signup and view all the answers

What is one effect of tobacco mentioned in the content?

<p>Increased cancer risk (C)</p> Signup and view all the answers

What type of injury relates to atmospheric pressure?

<p>Barotrauma (D)</p> Signup and view all the answers

Which of the following substances is associated with health risks once inhaled?

<p>Radon (B)</p> Signup and view all the answers

What is the primary way xenobiotics enter the body?

<p>Through inhalation, ingestion, and skin contact (A)</p> Signup and view all the answers

Which pollutants are commonly identified as important air pollutants?

<p>Ozone, sulfur dioxide, acid aerosols, and particles less than 10 μm (D)</p> Signup and view all the answers

What role does the cytochrome P-450 system play in the metabolism of xenobiotics?

<p>It converts xenobiotics into inactive or toxic metabolites. (D)</p> Signup and view all the answers

What is one significant health risk associated with carbon monoxide (CO) exposure?

<p>Systemic asphyxiation due to binding hemoglobin (D)</p> Signup and view all the answers

What two-phase reaction process is involved in the metabolism of xenobiotics?

<p>Phase I and Phase II reactions (D)</p> Signup and view all the answers

How can environmental factors influence disease development?

<p>By acting as stressors that impact immune function (B)</p> Signup and view all the answers

Which of the following methods is NOT a way that toxins can be eliminated from the body?

<p>Absorption into tissue (B)</p> Signup and view all the answers

What is a significant characteristic of indoor air pollutants?

<p>They tend to accumulate and cause disease. (C)</p> Signup and view all the answers

What is one of the major health risks associated with smoking?

<p>Increased risk of lung cancer (B)</p> Signup and view all the answers

How does tobacco consumption affect the risk of cancer associated with alcohol?

<p>It multiplies the risk of oral and esophageal cancers. (C)</p> Signup and view all the answers

What effect does maternal smoking have on pregnancy outcomes?

<p>Increased risk of spontaneous abortion and growth retardation (C)</p> Signup and view all the answers

What chronic respiratory conditions are linked to smoking?

<p>Emphysema and chronic bronchitis (B)</p> Signup and view all the answers

What is the estimated annual number of premature deaths in the USA due to tobacco use?

<p>440,000 (D)</p> Signup and view all the answers

What is a cardiovascular risk associated with tobacco use?

<p>Development of atherosclerosis (D)</p> Signup and view all the answers

Which form of tobacco is particularly associated with oral cancers?

<p>Smokeless tobacco (D)</p> Signup and view all the answers

What is a significant consequence of tobacco use while exposed to carcinogens like asbestos?

<p>It multiplies the risk of lung cancer. (A)</p> Signup and view all the answers

What is identified as a common cause of cancer related to toxic substances?

<p>Tobacco smoke (C)</p> Signup and view all the answers

Which cancer type is commonly associated with tobacco use?

<p>Squamous Cell Carcinoma (B)</p> Signup and view all the answers

What type of tumor might a non-smoker present with that resembles squamous cell carcinoma?

<p>Poorly-differentiated type of tumor (D)</p> Signup and view all the answers

Which of the following is NOT typically used to diagnose a non-smoker's cancer accurately?

<p>Smoking history (A)</p> Signup and view all the answers

What significant health-related monetary cost is attributed to preventable causes of death in the U.S.?

<p>$150 billion (D)</p> Signup and view all the answers

Which of the following diseases is NOT linked to toxic waste exposure?

<p>Allergic reactions (A)</p> Signup and view all the answers

Which of the following substances is commonly found in toxic waste dumps and is known for its carcinogenic properties?

<p>Vinyl Chloride (A)</p> Signup and view all the answers

What is regarded as the most preventable cause of death in the United States?

<p>Tobacco use (D)</p> Signup and view all the answers

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