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What is the primary function of essential fat in the body?
What is the primary function of essential fat in the body?
What is the typical range of stored fat for men associated with optimum health?
What is the typical range of stored fat for men associated with optimum health?
What is the leading predictor of childhood obesity?
What is the leading predictor of childhood obesity?
What is the estimated loss of years associated with being obese at age 40 for women?
What is the estimated loss of years associated with being obese at age 40 for women?
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Which of the following describes hypertrophy in adipocytes?
Which of the following describes hypertrophy in adipocytes?
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What significant trend has been observed among Canadian children aged 7-13 years?
What significant trend has been observed among Canadian children aged 7-13 years?
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Which enzyme is associated with the storage of fat in the body and is influenced by body weight changes?
Which enzyme is associated with the storage of fat in the body and is influenced by body weight changes?
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What is the primary hormone that drives appetite according to the document?
What is the primary hormone that drives appetite according to the document?
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What is a significant factor affecting the likelihood of becoming obese for men and women?
What is a significant factor affecting the likelihood of becoming obese for men and women?
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How are food swamps and food deserts defined?
How are food swamps and food deserts defined?
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When does the greatest level of fatness occur in normal growth for infants?
When does the greatest level of fatness occur in normal growth for infants?
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How does hypothyroidism primarily affect metabolism?
How does hypothyroidism primarily affect metabolism?
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What is the relationship between a mother's activity level and her daughter's activity level?
What is the relationship between a mother's activity level and her daughter's activity level?
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Why is it easier to maintain a healthy weight than to lose weight?
Why is it easier to maintain a healthy weight than to lose weight?
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What is primarily involved in the mobilization of triglycerides in adipocytes?
What is primarily involved in the mobilization of triglycerides in adipocytes?
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What percentage of Canadian boys aged 7-13 years had obesity rates rise from 5% to?
What percentage of Canadian boys aged 7-13 years had obesity rates rise from 5% to?
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What is one significant cause contributing to the obesity crisis?
What is one significant cause contributing to the obesity crisis?
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Which statement best describes 'immutable' in the context of obesity?
Which statement best describes 'immutable' in the context of obesity?
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What role does 'enculturation' play regarding obesity and portion sizes?
What role does 'enculturation' play regarding obesity and portion sizes?
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Which factor is classified as a controllable factor in weight management?
Which factor is classified as a controllable factor in weight management?
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How does technology contribute to the obesity crisis?
How does technology contribute to the obesity crisis?
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What is one of the physiological factors that may influence obesity?
What is one of the physiological factors that may influence obesity?
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Which of the following is an uncontrollable factor affecting body composition?
Which of the following is an uncontrollable factor affecting body composition?
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What is the implication of the phrase 'more in than out' in relation to obesity?
What is the implication of the phrase 'more in than out' in relation to obesity?
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Which hormone is identified as a powerful anorexic factor that decreases appetite?
Which hormone is identified as a powerful anorexic factor that decreases appetite?
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What happens to endorphin levels when a person experiences hunger?
What happens to endorphin levels when a person experiences hunger?
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Which neurotransmitter level increases during hunger?
Which neurotransmitter level increases during hunger?
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What is a consequence of entering a hypothyroid state during starvation?
What is a consequence of entering a hypothyroid state during starvation?
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What is a significant challenge faced in managing obesity according to contemporary models?
What is a significant challenge faced in managing obesity according to contemporary models?
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What does metabolic syndrome predict in the context of obesity?
What does metabolic syndrome predict in the context of obesity?
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Why is the reward pathway significant in discussing obesity?
Why is the reward pathway significant in discussing obesity?
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What demographic trends are observed in obesity rates among Canadians?
What demographic trends are observed in obesity rates among Canadians?
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What is one of the goals of pharmacologic management in dietary management?
What is one of the goals of pharmacologic management in dietary management?
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Which type of medication acts in the brain to increase the availability of norepinephrine?
Which type of medication acts in the brain to increase the availability of norepinephrine?
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What is a potential side effect of CNS-acting appetite suppressants?
What is a potential side effect of CNS-acting appetite suppressants?
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What is the primary purpose of bariatric surgery?
What is the primary purpose of bariatric surgery?
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What is an important aspect of post-operative care for bariatric surgery patients?
What is an important aspect of post-operative care for bariatric surgery patients?
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Which of the following describes gastric restriction?
Which of the following describes gastric restriction?
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Which statement best illustrates a key component of dietary management?
Which statement best illustrates a key component of dietary management?
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What characterizes non-CNS-acting agents in pharmacologic management?
What characterizes non-CNS-acting agents in pharmacologic management?
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Study Notes
Overweight and Obesity
- Overweight and obesity are a significant public health threat in North America, and most other developed nations.
- Parental obesity is a key predictor of childhood obesity.
- Childhood obesity increases all-cause mortality in adults.
- Being obese at 40 years of age associates with a loss of approximately 7 years of life for women and 6 years for life for men.
- Obesity rates for children (aged 7-13 years) in recent Canadian statistics have tripled in a generation.
- Overweight rates have increased in children (aged 7-13 years) from 15% to 35% in boys and 15% to 29% in girls.
- Canadians in higher-income households are less likely to become obese and suffer related chronic disease.
- It is easier to maintain a healthy weight than to lose weight and return to a healthy weight.
- The problem of overweight and obesity is more pronounced in children and is increasing at a more rapid pace.
- The Canadian Institutes of Health Research (CIHR) dedicated 100% of its funds to nutrition, metabolism, and diabetes research.
Causes of Obesity
- Obesity is caused by an imbalance of energy intake and expenditure.
- Unhealthy foods are easily accessible and the availability of food is a major factor.
- Lack of physical activity.
- Complex drives toward food.
- Appetite surpasses hunger.
- Portion sizes are increasing due to enculturation.
- Time constraints and the release of responsibility for food preparation.
- Changes in leisure time usage, including increasing use of technology.
- Limited nutritional education and misinformation.
- Lack of body composition awareness.
- Low energy expenditure during daily work.
- Influence of the food industry.
- Transportation technology and urban sprawl.
- Genetics and environment.
- Obesogens, which are chemical compounds that disrupt hormone function and contribute to weight gain.
Homeostasis and Body Composition
- Body composition: bone, muscle, organs, fluids, adipose tissue.
- Determining factors: homeostasis of body weight and/or body composition.
- Controllable factors: lifestyle and food choices.
- Uncontrollable factors include genetics, set point theory, and hormones such as: ghrelin, leptin, LPL, and HSL.
Adipose Tissue
- Adipose tissue is the primary storage site for excess energy, which predominantly occurs in adipocytes.
- There are two types of adipose tissue: white and brown.
- The location of fat storage is important: subcutaneous versus visceral fat.
- Android (abdominal) vs. Gynoid (hip) adiposity
- Optimum health is associated with 8%-24% total fat in men and 21%-35% total fat in women.
Adipocytes
- Hypertrophy: increase in adipocyte size.
- Hyperplasia: increase in adipocyte number.
- Adipocytes can store triglycerides up to 95% of their volume and can grow more than 1000 times.
- Hormone action influences the storage and mobilization of triglycerides in adipose tissue.
Lipogenesis
- Lipogenesis is the process of fat synthesis.
- Carbohydrates, protein, and dietary fat can be converted into fat.
- Kilocalories per gram: Fat=9, Carbohydrates=4, Protein=4.
- The fattening power of fat is higher than other macronutrients.
LPL and HSL
- Lipase enzyme: LPL and HSL play crucial roles in energy metabolism.
- LPL: lipoprotein lipase breaks down fat in the bloodstream and stores it in adipose tissue.
- HSL: hormone sensitive lipase breaks down fat stored in adipose tissue, allowing it to be used for energy.
- LPL and HSL are influenced by hormonal signals, including estrogens.
The Sympathetic Nervous System and Appetite
- Appetite is influenced by several hormones and neurotransmitters.
- Dopamine plays a key role and its rise is linked to increased appetite.
- After a meal, neurotransmitter levels shift, sending a slow/stop eating signal to the brain.
- During starvation: Hunger increases, satisfaction with food decreases, and metabolic rate decreases (hypothyroid state).
- Decreased activity in the sympathetic nervous system is linked to metabolic slowdown and weight gain.
Brain Chemistry and Appetite
- Fluctuations in brain neurotransmitter levels impact hunger, appetite, and intake.
- Neurotransmitters that increase appetite include:
- Decreased endorphin levels.
- Decreased serotonin levels.
- Increased neuropeptide Y levels.
- Increased dopamine and decreased norepinephrine levels.
Neurotransmitters During and After a Meal
- Corticotropic-releasing factor is released during and after a meal, which acts as a powerful anorexic factor (decreases appetite).
- Starvation results in a hypothyroid state, leading to increased hunger, diminished satisfaction with food, and slowed metabolism.
Obesity Management
- Weight loss and maintenance are important goals.
- While energy restriction was once the only treatment option, current models include lifestyle and behavior modification.
- Obesity management often requires an interdisciplinary healthcare team, including dietitians, healthcare providers, and psychological support professionals.
Dietary Management Recommendations
- Educational resources on diets and fads.
- Hunger and satiety cues, including psychological influences.
- Food education and understanding macronutrients.
- Implementing portion control.
- Focusing on caloric density of foods.
- Small, consistent changes to food intake.
- Emphasizing lifestyle choices rather than restrictive dieting.
- Encouraging physical activity.
Pharmacological Management
- Medications target appetite suppression, increased satiety, thermogenesis, metabolism, and fat absorption.
- CNS-acting agents: catecholamine’s (catecholaminergic), serotoninergic, catecholiminergic-serotoninergic, these influence appetite.
- Non-CNS-acting agents: orlistat (Xenical) impact fat absorption.
Surgical Procedures for Weight Loss (Bariatrics)
- Bariatrics is the medical specialty focused on weight control, including surgical procedures.
- Surgery is typically reserved for individuals with a BMI greater than 40, and only considered after non-surgical options have failed.
- Pre-surgical preparation includes: exercise routine, hypocaloric diet pattern, lifestyle modification, psychological counselling, and family support.
- Post-surgical follow-up is vital including lifestyle modification, psychological counselling, and dietary guidance.
Bariatric Surgery Types
- Common goals of bariatric surgery: reduce food consumption and absorption.
- Esophageal banding: reduces stomach capacity.
- Gastric restrictive surgery (Gastroplasty and Gastric bypass): reduce stomach size and bypass portions of the small intestine.
- Jejunoileal bypass: Surgical procedure that bypasses a portion of the small intestine (jejunum and ileum).
Gastric Restriction
- Surgical reduction of stomach volume.
- Large pocket of the stomach is closed off to reduce capacity.
- A portion of the small intestine may be bypassed as well.
- Effective in promoting weight loss, but maintenance can be challenging.
- Early satiety due to reduced stomach volume (20-30mL).
- Dumping syndrome can occur.
- Lifelong support after surgery is crucial.
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Description
Explore the critical public health issue of overweight and obesity, particularly focusing on its effects on children in North America. This quiz delves into causes, statistics, and the long-term health consequences of obesity, as well as the disparities observed in different income groups. Test your knowledge on this pressing health topic.