Overview of Vitamins
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Overview of Vitamins

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Questions and Answers

Which of the following is NOT a function of calcitriol?

  • Enhancing dietary vitamin D absorption
  • Stimulating red blood cell production (correct)
  • Promoting bone resorption
  • Maintaining plasma calcium levels
  • What is a consequence of vitamin D deficiency in adults?

  • Osteomalacia (correct)
  • Rickets
  • Hypercalcemia
  • Renal osteodystrophy
  • Which factor is NOT associated with vitamin D deficiency?

  • Poor dietary intake of vitamin D
  • Excess calcium absorption (correct)
  • Fat malabsorption syndromes
  • Inadequate sunlight exposure
  • What condition results from chronic renal failure and leads to a decreased ability to form active vitamin D?

    <p>Renal rickets</p> Signup and view all the answers

    What is a symptom of hypervitaminosis D?

    <p>Bone demineralization</p> Signup and view all the answers

    Which form of vitamin D is primarily measured to assess nutritional status?

    <p>25(OH)D3</p> Signup and view all the answers

    What is the active form of vitamin D known as?

    <p>Calcitriol</p> Signup and view all the answers

    Which vitamin E component is the most active?

    <p>Alpha-tocopherol</p> Signup and view all the answers

    Which vitamins are classified as fat soluble?

    <p>Vitamin A, D, E, K</p> Signup and view all the answers

    What is required for the digestion of fat soluble vitamins?

    <p>Bile acid</p> Signup and view all the answers

    Which food sources are rich in fat soluble vitamins?

    <p>Fatty part of food and liver</p> Signup and view all the answers

    What characterizes water soluble vitamins compared to fat soluble vitamins?

    <p>They are not toxic and stored in small amounts</p> Signup and view all the answers

    Which vitamin is chemically known as retinol?

    <p>Vitamin A</p> Signup and view all the answers

    What plays a significant role in the absorption of fat soluble vitamins?

    <p>Normal fat absorption</p> Signup and view all the answers

    Which of the following statements is true regarding water soluble vitamins?

    <p>They have a greater tendency for urinary excretion</p> Signup and view all the answers

    Which of the following is a product of β-carotene?

    <p>Vitamin A</p> Signup and view all the answers

    Which of the following foods is a rich source of thiamine?

    <p>Watermelon</p> Signup and view all the answers

    What is one of the primary functions of thiamine?

    <p>Acting as a coenzyme in carbohydrate metabolism</p> Signup and view all the answers

    What condition is caused by thiamine deficiency?

    <p>Beri-beri</p> Signup and view all the answers

    Which type of beri-beri primarily affects the cardiovascular system?

    <p>Wet beri-beri</p> Signup and view all the answers

    Which symptom is NOT associated with dry beri-beri?

    <p>Heart failure</p> Signup and view all the answers

    What syndrome is related to chronic alcoholism and thiamine deficiency?

    <p>Wernicke-Korsakoff syndrome</p> Signup and view all the answers

    What is a common symptom of infantile beriberi?

    <p>Tachycardia</p> Signup and view all the answers

    Which of the following is NOT a function of thiamine?

    <p>Regulation of blood sugar</p> Signup and view all the answers

    What is the primary role of Vitamin E in cellular membranes?

    <p>Blocks free radical chain reactions</p> Signup and view all the answers

    How does Vitamin E support reproductive functions?

    <p>By preserving germinal epithelium of gonads</p> Signup and view all the answers

    What can result from a deficiency of Vitamin E?

    <p>Megaloblastic anemia</p> Signup and view all the answers

    What source is particularly high in Vitamin E?

    <p>Oils and fats, especially wheat germ oil</p> Signup and view all the answers

    Which form of Vitamin E is most commonly measured in laboratories?

    <p>Alpha-tocopherol</p> Signup and view all the answers

    What role does Vitamin K play in the body?

    <p>Coenzyme in blood clotting and bone matrix formation</p> Signup and view all the answers

    Which vitamin is produced by intestinal bacteria?

    <p>Vitamin K2 (menaquinone)</p> Signup and view all the answers

    What is a rare symptom of Vitamin E toxicity?

    <p>Increased fragility of erythrocytes</p> Signup and view all the answers

    What is used to measure thiamine deficiency?

    <p>Enzyme transketolase activity</p> Signup and view all the answers

    What percentage increase in transketolase activity after adding TPP indicates thiamine deficiency?

    <p>25%</p> Signup and view all the answers

    Which of the following is a source of riboflavin?

    <p>Milk</p> Signup and view all the answers

    What condition is NOT commonly associated with riboflavin deficiency?

    <p>Anemia</p> Signup and view all the answers

    What is one of the biologically active forms of riboflavin?

    <p>Flavin mononucleotide (FMN)</p> Signup and view all the answers

    Which of the following is a symptom of riboflavin deficiency?

    <p>Skin rashes</p> Signup and view all the answers

    Which vitamin is known to be readily destroyed by ultraviolet sunlight?

    <p>Riboflavin (Vitamin B2)</p> Signup and view all the answers

    What are the two types of niacin?

    <p>Nicotinic acid and nicotinamide</p> Signup and view all the answers

    Study Notes

    Overview of Vitamins

    • Essential organic nutrients required in small amounts for various biochemical functions.
    • Cannot be synthesized by the body; must be obtained through diet.
    • Classified as fat-soluble (A, D, E, K) or water-soluble (B complex, C).

    Fat-Soluble Vitamins

    • Require bile acids for digestion and are transported in blood as chylomicrons to the liver.
    • Efficient absorption depends on normal fat absorption; stored in the liver and adipose tissue.
    • Higher risk of toxicity compared to deficiencies.
    • Good sources include fatty foods and liver.

    Water-Soluble Vitamins

    • Generally non-toxic; must be continuously supplied in the diet.
    • Stored in small amounts; greater loss occurs via urinary excretion.
    • Function primarily as coenzymes in enzymatic reactions.

    Vitamin A

    • Derived from β-carotene and is chemically known as retinol.
    • Sources include animal-derived foods (meat, liver, fish oils) and fortified products (milk, margarine).
    • Important for maintaining plasma calcium levels (normal range: 9-11 mg/dl).

    Vitamin D Functions and Deficiency

    • Deficiency leads to rickets in children and osteomalacia in adults.
    • Causes include insufficient dietary intake, limited sunlight exposure, absorption issues, and abnormal conversion to active metabolites.
    • Chronic renal failure can lead to renal rickets due to inadequate active vitamin D formation.

    Symptoms of Vitamin D Deficiency

    • Characterized by bowed legs and beaded ribs in rickets.

    Hypervitaminosis D

    • Toxic effects include bone resorption and hypercalcemia.
    • Symptoms: loss of appetite, nausea, increased thirst, and weight loss.
    • Key measurements include serum levels of 25(OH)D3 and 1,25(OH)2D3.

    Vitamin E

    • Composed of eight tocopherols; α-tocopherol is the most active form.
    • Acts as a terminal electron acceptor in cell membranes and protects against lipid peroxidation.
    • Major sources are oils (especially wheat germ oil), nuts, meat, milk, and eggs.
    • Deficiency symptoms include increased fragility of erythrocytes and minor neurological issues.

    Vitamin K

    • Exists as phylloquinone (K1, from plants) and menaquinone (K2, produced by intestinal bacteria).
    • Plays a crucial role in blood clotting and bone matrix formation, with sources including pork, whole grains, and legumes.

    Thiamine (Vitamin B₁)

    • Acts as a co-enzyme in carbohydrate metabolism and branched-chain amino acid metabolism.
    • Deficiency leads to ‘beri-beri’, affecting organs with high aerobic metabolism, notably the heart and nervous system.
    • Symptoms include wet beri-beri (cardiovascular issues) and dry beri-beri (neurological symptoms).

    Wernicke-Korsakoff Syndrome

    • Associated with chronic alcoholism, resulting from dietary insufficiency or impaired absorption, causing memory loss and ocular symptoms.

    Measurement of Thiamine

    • Evaluated by transketolase activity in erythrocytes; deficiency indicated by >25% increase after TPP addition.
    • Detection methods include HPLC.

    Riboflavin (Vitamin B₂)

    • Exists in active forms: FMN and FAD, which are crucial for oxidation-reduction reactions.
    • Sources include milk, liver, eggs, and leafy vegetables.
    • Deficiency may cause dermatitis, cheilosis, and glossitis; not associated with major diseases.

    Niacin (Vitamin B₃)

    • Composed of two forms: nicotinic acid and nicotinamide.

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    Description

    This quiz provides an overview of vitamins, highlighting their essential roles as organic nutrients and their classifications as fat-soluble and water-soluble. You'll learn about their digestion, absorption, and storage in the body, alongside potential toxicity risks. Test your knowledge on the critical functions these nutrients serve in maintaining health.

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