Overview of Type 2 Diabetes
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Overview of Type 2 Diabetes

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Questions and Answers

What is a primary characteristic of Type 2 Diabetes?

  • Inadequate production of insulin from the pancreas
  • Elevated insulin secretion post meals
  • Autoimmune destruction of beta-cells
  • Insulin resistance in body cells (correct)
  • Which of the following is a commonly recognized risk factor for developing Type 2 Diabetes?

  • Regular intense exercise
  • Increase in age after 45 years (correct)
  • High carbohydrate intake from fruits
  • Low protein diet
  • What is the fasting plasma glucose level that indicates diabetes?

  • ≥ 140 mg/dL
  • ≥ 120 mg/dL
  • ≥ 126 mg/dL (correct)
  • ≥ 100 mg/dL
  • Which lifestyle modification is recommended for managing Type 2 Diabetes?

    <p>Regular physical activity of at least 150 minutes per week</p> Signup and view all the answers

    Which medication is typically considered the first-line treatment for Type 2 Diabetes?

    <p>Metformin</p> Signup and view all the answers

    What symptom can be indicative of Type 2 Diabetes?

    <p>Frequent urination</p> Signup and view all the answers

    Which complication is specifically linked to long-term uncontrolled Type 2 Diabetes?

    <p>Kidney failure (diabetic nephropathy)</p> Signup and view all the answers

    Which dietary choice can aid in the prevention of Type 2 Diabetes?

    <p>Increased consumption of whole grains</p> Signup and view all the answers

    Study Notes

    Overview of Type 2 Diabetes

    • Chronic condition affecting how the body metabolizes glucose.
    • Characterized by insulin resistance and/or inadequate insulin secretion.

    Risk Factors

    1. Genetic: Family history of diabetes.
    2. Age: Increased risk after 45 years.
    3. Weight: Obesity, particularly abdominal fat.
    4. Physical Inactivity: Sedentary lifestyle.
    5. Ethnicity: Higher prevalence in certain populations (e.g., African American, Hispanic, Native American).
    6. Diet: High intake of processed foods, sugary beverages, and unhealthy fats.

    Pathophysiology

    • Insulin Resistance: Body's cells do not respond effectively to insulin.
    • Beta-Cell Dysfunction: Impaired insulin secretion from pancreas over time.
    • Increased Glucose Production: Liver produces more glucose inappropriately.

    Symptoms

    • Increased thirst (polydipsia).
    • Frequent urination (polyuria).
    • Increased hunger (polyphagia).
    • Fatigue.
    • Blurred vision.
    • Slow-healing wounds or frequent infections.

    Diagnosis

    • Fasting Plasma Glucose Test: ≥ 126 mg/dL.
    • Oral Glucose Tolerance Test: ≥ 200 mg/dL after 2 hours.
    • A1C Test: ≥ 6.5% for diabetes diagnosis.

    Management

    1. Lifestyle Modifications:

      • Diet: Balanced diet rich in whole grains, fruits, vegetables, lean proteins, and healthy fats.
      • Exercise: Regular physical activity (150 minutes/week recommended).
      • Weight management: Loss of 5-10% of body weight can improve control.
    2. Medication:

      • Metformin: First-line oral medication.
      • Other options: Sulfonylureas, GLP-1 receptor agonists, SGLT2 inhibitors.
    3. Monitoring:

      • Regular blood glucose monitoring.
      • Periodic A1C tests to assess long-term control.
      • Check-ups for complications (retinopathy, nephropathy, neuropathy).

    Complications

    • Short-term: Hyperglycemia, hypoglycemia.
    • Long-term:
      • Cardiovascular disease.
      • Kidney failure (diabetic nephropathy).
      • Nerve damage (diabetic neuropathy).
      • Eye problems (diabetic retinopathy).
      • Increased risk of foot injuries and infections.

    Prevention

    • Healthy eating: Emphasis on fiber and whole foods.
    • Regular physical activity: Maintain a healthy weight.
    • Regular health check-ups to monitor risk factors.

    Type 2 Diabetes Overview

    • Chronic condition affecting how the body utilizes glucose
    • Characterized by insulin resistance and/or inadequate insulin secretion

    Risk Factors

    • Genetic: Family history of diabetes increases risk
    • Age: Risk increases after 45 years
    • Weight: Obesity, particularly abdominal fat, raises risk
    • Physical Inactivity: Sedentary lifestyle contributes to risk
    • Ethnicity: Certain populations, such as African Americans, Hispanics, and Native Americans, have a higher prevalence
    • Diet: High intake of processed foods, sugary beverages, and unhealthy fats increases risk

    Pathophysiology

    • Insulin Resistance: Body's cells do not respond effectively to insulin
    • Beta-Cell Dysfunction: Impaired insulin secretion from pancreas develops over time
    • Increased Glucose Production: Liver produces excess glucose inappropriately

    Symptoms

    • Increased thirst (polydipsia)
    • Frequent urination (polyuria)
    • Increased hunger (polyphagia)
    • Fatigue
    • Blurred vision
    • Slow-healing wounds or frequent infections

    Diagnosis

    • Fasting Plasma Glucose Test: A value of ≥ 126 mg/dL indicates diabetes
    • Oral Glucose Tolerance Test: A value of ≥ 200 mg/dL after 2 hours indicates diabetes
    • A1C Test: A value of ≥ 6.5% indicates diabetes

    Management

    • Lifestyle Modifications:
      • Diet: Balanced diet rich in whole grains, fruits, vegetables, lean proteins, and healthy fats
      • Exercise: Regular physical activity (150 minutes/week recommended)
      • Weight management: Loss of 5-10% of body weight can significantly improve control
    • Medication:
      • Metformin: First-line oral medication
      • Other options: Sulfonylureas, GLP-1 receptor agonists, SGLT2 inhibitors
    • Monitoring:
      • Regular blood glucose monitoring
      • Periodic A1C tests to assess long-term control
      • Check-ups for complications (retinopathy, nephropathy, neuropathy)

    Complications

    • Short-term: Hyperglycemia, hypoglycemia
    • Long-term:
      • Cardiovascular disease
      • Kidney failure (diabetic nephropathy)
      • Nerve damage (diabetic neuropathy)
      • Eye problems (diabetic retinopathy)
      • Increased risk of foot injuries and infections

    Prevention

    • Healthy eating: Emphasis on fiber and whole foods
    • Regular physical activity: Maintain a healthy weight
    • Regular health check-ups to monitor risk factors

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    Description

    This quiz explores the essentials of Type 2 Diabetes, a chronic condition affecting glucose metabolism. It covers risk factors, pathophysiology, and symptoms that characterize this prevalent disease. Enhance your understanding of this condition and its impact on health.

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