Overview of Immunity

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Questions and Answers

What are the two hormones released by the posterior pituitary gland?

  • Oxytocin and antidiuretic hormone (ADH) (correct)
  • Growth hormone and prolactin
  • Oxytocin and prolactin
  • Growth hormone and antidiuretic hormone (ADH)

Which of the following is NOT a function of thyroid hormones?

  • Regulate blood calcium levels (correct)
  • Increase body temperature
  • Promote protein synthesis
  • Increase basal metabolic rate

Which of the following is a steroid hormone?

  • Insulin
  • Growth Hormone
  • Testosterone (correct)
  • Epinephrine

The ______ gland is located anterior to the trachea and inferior to the larynx.

<p>thyroid</p> Signup and view all the answers

The pancreas has both exocrine and endocrine functions.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a function of the liver?

<p>Regulate blood calcium levels (B)</p> Signup and view all the answers

The small intestine is the main site of nutrient absorption.

<p>True (A)</p> Signup and view all the answers

What are the four main layers of the gastrointestinal tract wall?

<p>Mucosa, submucosa, muscularis, and serosa</p> Signup and view all the answers

Which of the following is the main function of the salivary glands?

<p>Moistening and lubricating food (B)</p> Signup and view all the answers

The ______ is the functional unit of the kidney.

<p>nephron</p> Signup and view all the answers

Which of the following is NOT a component of the renal corpuscle?

<p>Proximal convoluted tubule (B)</p> Signup and view all the answers

Glomerular filtration is a passive process driven by net filtration pressure.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a major process involved in urine formation?

<p>Diffusion (A)</p> Signup and view all the answers

Where does most solute and water reabsorption occur in the nephron?

<p>Proximal convoluted tubule</p> Signup and view all the answers

The descending limb of the loop of Henle is permeable to water but impermeable to solutes.

<p>True (A)</p> Signup and view all the answers

Which hormone is primarily responsible for regulating blood pressure?

<p>Aldosterone (C)</p> Signup and view all the answers

The juxtaglomerular apparatus (JGA) is involved in regulating glomerular filtration rate (GFR).

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a function of the collecting ducts in the kidney?

<p>Reabsorb glucose (C)</p> Signup and view all the answers

The human body is primarily composed of water.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a major component of the ICF?

<p>Sodium (A)</p> Signup and view all the answers

What is the primary mechanism of water movement between body fluid compartments?

<p>Osmosis</p> Signup and view all the answers

Which of the following is NOT a common cause of edema?

<p>Increased blood pressure (C)</p> Signup and view all the answers

Dehydration can lead to a decrease in blood pressure.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a function of electrolytes in the body?

<p>Production of hormones (A)</p> Signup and view all the answers

The most abundant electrolyte in the extracellular fluid (ECF) is sodium.

<p>True (A)</p> Signup and view all the answers

Which of the following is a typical sign of hyperkalemia?

<p>Muscle weakness (A)</p> Signup and view all the answers

The kidneys play a major role in regulating acid-base balance in the body.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a common cause of metabolic acidosis?

<p>Hyperventilation (A)</p> Signup and view all the answers

The body can compensate for pH imbalances through both respiratory and metabolic mechanisms.

<p>True (A)</p> Signup and view all the answers

Which of the following is the main hormone that stimulates the release of eggs from the ovaries?

<p>Luteinizing hormone (LH) (A)</p> Signup and view all the answers

The menstrual cycle is a series of events that occur in both the ovaries and the uterus.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a phase of the uterine cycle?

<p>Follicular phase (C)</p> Signup and view all the answers

Human chorionic gonadotropin (hCG) is produced by the developing embryo during pregnancy.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a component of semen?

<p>Uterine fluid (B)</p> Signup and view all the answers

What is the primary function of the penis?

<p>To deliver sperm into the vagina during intercourse.</p> Signup and view all the answers

The scrotum helps to regulate the temperature of the testes.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a function of the lymphatic system?

<p>Nutrient absorption (C)</p> Signup and view all the answers

Lymph nodes act as filters, trapping pathogens and stimulating immune responses.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a type of white blood cell?

<p>Red blood cells (A)</p> Signup and view all the answers

The innate immune system is the body's first line of defense against pathogens.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a characteristic of the adaptive immune system?

<p>Rapid response (D)</p> Signup and view all the answers

Antigens are molecules that the body recognizes as 'self'.

<p>False (B)</p> Signup and view all the answers

Which of the following cells is responsible for secreting antibodies?

<p>B cells (B)</p> Signup and view all the answers

Memory cells are a key feature of the adaptive immune system, allowing for a faster and more effective response to subsequent exposures to the same pathogen.

<p>True (A)</p> Signup and view all the answers

The primary immune response is generally slower and less effective than the secondary immune response.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT one of the five major classes of antibodies?

<p>IgF (C)</p> Signup and view all the answers

Flashcards

Endocrine system

The internal communication system that uses hormones to regulate various bodily functions.

Hormones

Chemical messengers produced by endocrine glands and secreted into the bloodstream to target specific cells.

Paracrine signaling

A type of cell signaling where hormones act on neighboring cells.

Autocrine signaling

A type of cell signaling where hormones act on the same cell that released them.

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Endocrine signaling

The type of cell signaling used by the endocrine system, where hormones travel through the bloodstream to target cells throughout the body.

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Exocrine glands

Glands that secrete their products into ducts, which then carry the secretions to a specific location within or outside the body.

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Endocrine glands

Glands that secrete hormones directly into the bloodstream or interstitial fluid, reaching target cells through circulation.

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Target cell response

The ability of a hormone to affect a target cell.

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Steroid hormones

Hormones derived from cholesterol, which are lipid-soluble and can easily pass through cell membranes.

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Amine hormones

Hormones derived from modified amino acids, which are water-soluble but cannot cross cell membranes.

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Peptide and protein hormones

Hormones composed of chains of amino acids, which are also water-soluble and cannot cross cell membranes.

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Intracellular hormone receptors

Receptors located inside the target cell, typically in the cytoplasm or nucleus. These receptors bind to steroid and thyroid hormones.

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Membrane-bound hormone receptors

Receptors located on the cell membrane, binding to water-soluble hormones such as amine and peptide hormones.

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Second messenger system

A signalling pathway within the cell that involves a series of molecules, including a hormone, a G protein, adenylyl cyclase, and cAMP.

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Pituitary gland

The gland located at the base of the brain, responsible for secreting various hormones.

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Hypothalamus

The region of the brain that regulates the secretion of hormones from the pituitary gland.

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Growth hormone (GH)

A hormone that promotes growth and development.

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Thyroid-stimulating hormone (TSH)

The hormone that stimulates the release of thyroid hormones from the thyroid gland.

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Insulin

A hormone that regulates many metabolic processes, including blood sugar.

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Glucagon

A hormone that raises blood sugar levels.

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Thyroid gland

The gland located in the neck, responsible for producing thyroid hormones.

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Thyroid hormones (T3 and T4)

The hormones produced by the thyroid gland, which are essential for metabolism and development.

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Calcitonin

A hormone that lowers blood calcium levels.

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Parathyroid glands

The small glands located on the posterior of the thyroid gland, responsible for controlling blood calcium levels.

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Parathyroid hormone (PTH)

A hormone that increases blood calcium levels.

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Adrenal glands

The glands situated on top of the kidneys, responsible for secreting numerous hormones.

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Adrenal cortex

The outer portion of the adrenal glands, secreting hormones such as cortisol.

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Adrenal medulla

The inner portion of the adrenal glands, secreting hormones like epinephrine (adrenaline) and norepinephrine.

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Aldosterone

A hormone that regulates blood pressure and electrolyte balance.

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Cortisol

A hormone released in response to stress, which helps the body cope with challenging situations.

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Pancreas

The organ responsible for producing digestive enzymes and hormones.

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Pancreatic juice

A digestive juice produced by the pancreas, containing enzymes that break down proteins, carbohydrates, and lipids.

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Study Notes

Overview of Immunity

  • Immunity is a complex system of defenses in the body
  • It protects against pathogens like bacteria, viruses, and fungi

Innate Immunity

  • Provides immediate, non-specific defenses
  • Includes physical barriers like skin and mucous membranes
  • Also involves cellular responses like phagocytosis by macrophages, neutrophils, and dendritic cells
  • Some chemical defenses include lysozyme and complement proteins

Adaptive Immunity

  • Provides a slower, highly specific response to pathogens
  • Involves lymphocytes (T cells and B cells)
  • T-cells identify and destroy infected cells.
  • B cells produce antibodies that target specific pathogens
  • It has memory, so subsequent responses are faster and more effective

Components of the Immune System

  • Lymphocytes: white blood cells that are key components of adaptive immunity. There are T cells and B cells.
  • Antibodies: proteins produced by B cells that bind to specific antigens
  • Antigens: molecules on the surface of pathogens that are recognized by the immune system
  • Antigen-presenting cells (APCs): cells that present antigens to other immune cells, activating the adaptive immune response

Overview of the Lymphatic System

  • A network of vessels, cells, and organs involved in fluid balance and immune responses.
  • Lymphatic capillaries collect excess interstitial fluid and return it to the bloodstream.
  • Lymph nodes filter lymph, removing pathogens and debris.
  • Spleen and thymus are additional lymphoid organs that play key roles in immune responses.

Mechanisms of Immune Response

  • Phagocytosis: engulfment and destruction of pathogens by immune cells.
  • Inflammation: a localized response to injury or infection characterized by redness, swelling, heat, and pain.
  • Cytotoxic T-cell activity: directly destroying infected cells.
  • Antibody-mediated immunity: involves antibodies binding to antigens, marking them for destruction by other immune cells or preventing pathogen entry.

Other Important Concepts

  • Immune memory: allows for faster and more effective responses upon subsequent exposures to the same pathogen.
  • Immunological tolerance: the ability of the immune system to distinguish between self and non-self, preventing harmful attacks on the body's own tissues.
  • Autoimmune diseases: occur when the immune system attacks the body's own tissues.

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