Overview of Glycolysis Process

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What is the main function of glycolysis?

Convert glucose to pyruvate and ATP (correct)

Prevent movement of substrates through enzymes

Produce toxic intermediates

Generate 4 ATP

Which enzyme is responsible for transferring a phosphoryl group from ATP to glucose?

Hexokinase (correct)

Isomerase

Phosphorylase

Kinase

In glycolysis, what is the compound that can be cleaved into two phosphorylated 3-carbon molecules?

Glyceraldehyde 3-phosphate

Fructose 1,6-bisphosphate (correct)

Glucose 6-phosphate

Dihydroxyacetone phosphate

Which stage of glycolysis involves the trapping and preparation phase?

Stage 1 Signup and view all the answers

What is the net yield of ATP in glycolysis?

2 ATP Signup and view all the answers

Which enzyme helps in the conversion of glucose to fructose 1,6-bisphosphate in glycolysis?

Phosphofructokinase Signup and view all the answers

What is the function of substrate channeling in glycolysis?

Ensures movement of substrates and products through enzymes Signup and view all the answers

Which part of glycolysis involves ATP harvesting?

Stage 2 Signup and view all the answers

Which enzyme catalyzes the conversion of galactose 1-phosphate to UDP-galactose?

Galactose 1-phosphate uridyl transferase Signup and view all the answers

What is the role of UDP-galactose 4-epimerase in the pathway?

Converts UDP-galactose to UDP-glucose Signup and view all the answers

Which of the following statements about glucose 1-phosphate is correct?

It is converted to glucose 6-phosphate by phosphoglucomutase Signup and view all the answers

Which enzyme in glycolysis is regulated by allosteric effectors or covalent modification, serving as a control point?

Hexokinase Signup and view all the answers

In muscle cells, how is glycolysis primarily regulated?

By allosteric regulation of phosphofructokinase by ATP and AMP Signup and view all the answers

Which statement about hexokinase in muscle cells is correct?

It is inhibited by glucose 6-phosphate Signup and view all the answers

Which of the following statements about glucose metabolism in the liver is true?

Glucose metabolism in the liver is highly versatile, involving various processes Signup and view all the answers

How is phosphofructokinase in the liver regulated?

By allosteric regulation by citrate and fructose 2,6-bisphosphate Signup and view all the answers

What is a key feature of glucokinase in the liver, unlike hexokinase?

It has a high affinity for glucose and is not inhibited by glucose 6-phosphate Signup and view all the answers

Which of the following statements about gluconeogenesis is correct?

It is regulated by fructose 1,6-bisphosphatase and glucose 6-phosphatase Signup and view all the answers

What is the role of phosphoglucose isomerase in glycolysis?

It converts glucose 6-phosphate to fructose 6-phosphate Signup and view all the answers

Which enzyme catalyzes the irreversible reaction of fructose 6-phosphate to fructose 1,6-bisphosphate?

Phosphofructokinase (PFK) Signup and view all the answers

Which enzyme catalyzes the oxidation-reduction reaction of glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate in stage 2 of glycolysis?

Glyceraldehyde 3-phosphate dehydrogenase Signup and view all the answers

What is the role of phosphoglycerate kinase in glycolysis?

It catalyzes the formation of ATP by transferring a phosphoryl group from 1,3-bisphosphoglycerate to ADP Signup and view all the answers

What is the net reaction of the conversion of glucose to pyruvate in glycolysis?

Glucose + 2 Pi + 2 ADP + 2 NAD+ 2 pyruvate + 2 ATP + 2 NADH + 2 H+ + H2O Signup and view all the answers