23 Questions
What is the main function of glycolysis?
Convert glucose to pyruvate and ATP
Which enzyme is responsible for transferring a phosphoryl group from ATP to glucose?
Hexokinase
In glycolysis, what is the compound that can be cleaved into two phosphorylated 3-carbon molecules?
Fructose 1,6-bisphosphate
Which stage of glycolysis involves the trapping and preparation phase?
Stage 1
What is the net yield of ATP in glycolysis?
2 ATP
Which enzyme helps in the conversion of glucose to fructose 1,6-bisphosphate in glycolysis?
Phosphofructokinase
What is the function of substrate channeling in glycolysis?
Ensures movement of substrates and products through enzymes
Which part of glycolysis involves ATP harvesting?
Stage 2
Which enzyme catalyzes the conversion of galactose 1-phosphate to UDP-galactose?
Galactose 1-phosphate uridyl transferase
What is the role of UDP-galactose 4-epimerase in the pathway?
Converts UDP-galactose to UDP-glucose
Which of the following statements about glucose 1-phosphate is correct?
It is converted to glucose 6-phosphate by phosphoglucomutase
Which enzyme in glycolysis is regulated by allosteric effectors or covalent modification, serving as a control point?
Hexokinase
In muscle cells, how is glycolysis primarily regulated?
By allosteric regulation of phosphofructokinase by ATP and AMP
Which statement about hexokinase in muscle cells is correct?
It is inhibited by glucose 6-phosphate
Which of the following statements about glucose metabolism in the liver is true?
Glucose metabolism in the liver is highly versatile, involving various processes
How is phosphofructokinase in the liver regulated?
By allosteric regulation by citrate and fructose 2,6-bisphosphate
What is a key feature of glucokinase in the liver, unlike hexokinase?
It has a high affinity for glucose and is not inhibited by glucose 6-phosphate
Which of the following statements about gluconeogenesis is correct?
It is regulated by fructose 1,6-bisphosphatase and glucose 6-phosphatase
What is the role of phosphoglucose isomerase in glycolysis?
It converts glucose 6-phosphate to fructose 6-phosphate
Which enzyme catalyzes the irreversible reaction of fructose 6-phosphate to fructose 1,6-bisphosphate?
Phosphofructokinase (PFK)
Which enzyme catalyzes the oxidation-reduction reaction of glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate in stage 2 of glycolysis?
Glyceraldehyde 3-phosphate dehydrogenase
What is the role of phosphoglycerate kinase in glycolysis?
It catalyzes the formation of ATP by transferring a phosphoryl group from 1,3-bisphosphoglycerate to ADP
What is the net reaction of the conversion of glucose to pyruvate in glycolysis?
Glucose + 2 Pi + 2 ADP + 2 NAD+ 2 pyruvate + 2 ATP + 2 NADH + 2 H+ + H2O
Learn about the common pathway of glycolysis present in both prokaryotic and eukaryotic cells, where glucose is converted into pyruvate and ATP. Understand the different stages involved in glycolysis and how enzymes play a crucial role in substrate channeling and product movement.
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