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Questions and Answers
Why is herd immunity considered important for community health?
What is a major consequence of overusing antibiotics?
Which of the following statements about antibiotics is true?
How can individuals help reduce antibiotic resistance?
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Which of the following statements regarding antibiotic resistance is correct?
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What is the primary method through which fungi reproduce?
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Which infection is NOT caused by fungi?
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Why are viruses not considered living organisms?
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Which of the following is a common feature of all viruses?
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What is the first step in the reproductive cycle of a virus?
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Which of the following diseases is a viral infection?
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What public health strategy helps authorities assess risks during an outbreak?
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Which of the following is NOT a strategy to stop the spread of diseases?
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Which disease is classified as an acquired non-communicable disease?
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Which of the following diseases is caused by a protozoan pathogen?
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What type of disease is cancer primarily classified as?
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Which of the following is a characteristic of congenital diseases?
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Which disease is transmitted through environmental factors rather than pathogens?
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What type of pathogen is responsible for causing thrush?
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Which of the following options is NOT a type of non-infectious disease?
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Which type of non-communicable disease is associated with lifestyle factors?
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What is the primary function of the body's first line of defence?
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Which of the following is NOT considered a physical barrier in the first line of defence?
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What role do Mast Cells play in the second line of defence?
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Which statement accurately describes the second line of defence?
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During which phase does the body experience redness, swelling, heat, and pain?
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What is the primary role of fever in the immune response?
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What is the purpose of chemical barriers in the first line of defence?
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Which of the following is an example of a biological barrier?
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Which of the following immune cells is NOT classified as a phagocyte?
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What happens during the incubation period after infection?
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What is a characteristic of the non-specific immune response?
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What distinguishes the third line of defense from the first and second lines of defense?
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What is the function of memory B cells in the immune system?
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How does the immune system differentiate between 'self' and 'non-self'?
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Which statement about B cells is true?
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What role do phagocytes play in the immune response?
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Study Notes
Diseases
- Diseases can be either congenital, acquired, or non-communicable/non-infectious.
- Congenital diseases are present at birth and are caused by genetic factors.
- Acquired diseases are developed after birth and can be caused by environmental factors, lifestyle choices, or infections.
- Non-communicable/non-infectious diseases are not caused by pathogens but can be caused by genetic factors, lifestyle choices, or environmental toxins.
Pathogens
- Pathogens are infectious agents that can cause disease.
- There are many types of pathogens, including bacteria, viruses, fungi, protozoa, and prions.
- Pathogens cause illnesses by invading the body and disrupting normal functions.
Fungi
- Fungi are found in air, soil, water, and on plants.
- They reproduce asexually through fragmentation, budding, or spore production.
- Fungal infections commonly start in the lungs or on the skin.
- Some examples of fungal infections include thrush, ringworm, and athlete's foot.
Viruses
- Viruses are tiny, infectious particles that cannot reproduce on their own and require a host cell to replicate.
- They "commandeer" host cells to produce more viruses, effectively reprogramming them.
- Viruses are not considered living organisms because they cannot reproduce independently.
- Antibiotics are ineffective against viruses.
Viral Structure and Reproduction
- Viruses have a protective protein shell called a capsid.
- The capsid encloses the virus's genetic material (DNA).
- The capsid allows the virus to attach to and infect host cells.
- Viral reproduction involves several steps: the virus injects its DNA into the host cell, the viral DNA gets replicated by the host cell's organelles, and thousands of new viruses are produced, eventually bursting the host cell and releasing them to infect other cells.
Examples of Viral Diseases
- Common viral diseases include polio, rabies, hepatitis, rubella, and COVID-19.
Preventing Disease Spread
- Strategies used to prevent disease spread vary depending on the pathogen and its mode of transmission.
- These include vaccination programs, risk assessment strategies like contact tracing and testing, movement restrictions like lockdowns, quarantines, and isolation, measures to reduce spread like masks, social distancing, and hand washing, treatment with antibiotics (for bacterial infections only) and antivirals, and social strategies such as public awareness campaigns, funding for vaccine research, public compliance and enforcement, and international cooperation.
The Immune System
- The human body has three lines of defense against disease.
First Line of Defense
- The first line of defense is a passive immune system and acts as a barrier to pathogens.
- This defense includes physical barriers (skin, cilia, nasal hairs), chemical barriers (saliva, tears, stomach acid), and biological barriers (good bacteria on skin and in the intestine).
Second Line of Defense
- The second line of defense is activated after pathogens have entered the body.
- It includes inflammation, fever, blood clotting, and phagocytosis.
- Inflammation is characterized by redness, swelling, heat, and pain.
- Fever increases body temperature, making it harder for pathogens to survive.
- Blood clots prevent pathogens from entering the bloodstream.
- Phagocytes, like macrophages, neutrophils, and monocytes, are immune cells that engulf and digest pathogens.
Third Line of Defense
- The third line of defense is a specific and acquired immune response.
- Lymphocytes, a type of white blood cell, are the key players in the third line of defense.
- There are two main types of lymphocytes: T cells and B cells.
- The third line of defense is specific because it targets specific pathogens.
- The third line of defense is acquired because it develops throughout an individual's life, based on exposure to pathogens.
- Immunological memory, provided by memory B cells, allows the body to remember and mount a faster and stronger response to previously encountered pathogens.
- Vaccines work by harnessing the body's immunological memory to provide immunity against specific diseases.
Antigens and Antibodies
- Pathogens contain foreign chemicals called antigens, which are recognized by the immune system as "non-self."
- The immune system distinguishes between "self" and "non-self" using antigens.
- B cells produce antibodies, which bind to specific antigens on pathogens and neutralize them.
T Cell Function
- T cells are a type of lymphocyte that directly attack and destroy infected host cells.
- T cells identify infected cells by recognizing foreign antigens on their surface.
Herd Immunity
- Herd immunity occurs when a significant proportion of the population is immune to a disease, making it difficult for the disease to spread.
- Vaccination is a key part of achieving herd immunity.
Antibiotics
- Antibiotics are drugs used to treat bacterial infections.
- They are not effective against viruses.
- Antibiotic resistance is a major public health concern.
Antibiotic Resistance
- Antibiotic overuse is a major cause of antibiotic resistance.
- Overuse of antibiotics creates superbugs, bacterial strains that are resistant to certain antibiotics.
- Antibiotic resistance makes bacterial infections more difficult to treat.
- The World Health Organization has declared antibiotic resistance a major global health threat.
Measures to Reduce Antibiotic Resistance
- Take antibiotics only for bacterial infections.
- Complete the full course of antibiotics as prescribed, even if you feel better.
- Avoid sharing antibiotics with others or using leftover prescriptions.
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Description
This quiz covers the fundamentals of diseases, including congenital, acquired, and non-communicable types. It also explores pathogens, their role in causing infections, and details on fungi as a specific pathogen. Test your knowledge on how these elements contribute to human health.