Osteoporosis Screening and Detection Quiz

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Questions and Answers

Which factor increases the probability of hip fracture by 30% for each standard deviation increase?

  • Recent MOF
  • Hip axis length (HAL) (correct)
  • Type II diabetes mellitus
  • Falls history

Which condition requires entering 'yes' in the rheumatoid arthritis input to FRAX?

  • Chronic renal disease
  • Recent MOF
  • Type II diabetes mellitus (correct)
  • Type I diabetes mellitus

Which characteristic has been shown to have little impact on FRAX values, according to the text?

  • Body composition variation
  • Socioeconomic status (correct)
  • Severity of vertebral fractures
  • Chronic renal disease

What adjustment should be used for type I diabetes until empirical data is available?

<p>Use the same adjustment as for type II diabetes (B)</p> Signup and view all the answers

Which factor results in marked uplift to fracture probabilities, as mentioned in the text?

<p>Recent MOF (B)</p> Signup and view all the answers

What should be entered into the rheumatoid arthritis input to FRAX for type II diabetes mellitus?

<p>'Yes' (D)</p> Signup and view all the answers

Which condition contributes to increased probability of major osteoporotic fracture (MOF) and hip fracture by 30% for a history of recurrent falls?

<p>Falls history (B)</p> Signup and view all the answers

What risk factor requires using the FRAX model for country of birth?

<p>Type I diabetes mellitus (A)</p> Signup and view all the answers

What are FRAX values largely unaffected by, according to the text?

<p>Body composition variation (C)</p> Signup and view all the answers

What has largely no empirical data from which to recommend an adjustment according to the text?

<p>Severity and/or number of vertebral fractures (A)</p> Signup and view all the answers

What is the recommended way to present numeric information to patients?

<p>Using whole numbers and simple frequencies (A)</p> Signup and view all the answers

Why is it mentioned that graphs and pictograms should be used where available?

<p>To simplify the understanding of numeric information (B)</p> Signup and view all the answers

What is the purpose of investigating osteoporosis and fragility fractures?

<p>To exclude diseases that mimic osteoporosis and identify the cause(s) of osteoporosis (C)</p> Signup and view all the answers

When should PTH be measured according to the text?

<p>If albumin-adjusted serum calcium is below 2.6mmol/l twice, or if below 2.5mmol/l twice if primary hyperparathyroidism is suspected (D)</p> Signup and view all the answers

What does CTX reflect according to the text?

<p>Bone resorption (A)</p> Signup and view all the answers

What are the recommended tests for investigating osteoporosis and fragility fractures?

<p>Erythrocyte sedimentation rate and C-reactive protein (A)</p> Signup and view all the answers

Why is vertebral fracture assessment (VFA) considered in high-risk individuals?

<p>To detect moderate or severe vertebral fractures which are strong risk factors for subsequent fracture (C)</p> Signup and view all the answers

What does opportunistically diagnosing osteoporosis and vertebral fractures involve according to the text?

<p>Identifying fractures from CT using Computer Aided Diagnostics acquired for various clinical reasons (C)</p> Signup and view all the answers

What does Vertebral Fracture Assessment (VFA) using lateral spine DXA imaging deliver according to the text?

<p>Lower radiation dose while performing comparably to traditional radiographs (B)</p> Signup and view all the answers

What can Computer Aided Diagnostics (CAD) using CT scans do according to the text?

<p>Augment and improve standard reporting methods for vertebral fracture identification (A)</p> Signup and view all the answers

What is the purpose of the Fracture Risk Assessment Tool (FRAX)?

<p>To predict the risk of hip or other major fractures over the next 10 years (C)</p> Signup and view all the answers

What is the evidence level for the effectiveness of the screening program using FRAX to reduce hip fractures?

<p>Evidence level Ia (C)</p> Signup and view all the answers

In addition to bone mineral density (BMD), what other factors can improve fracture risk prediction?

<p>Femoral neck BMD and height loss (B)</p> Signup and view all the answers

What strategy is appropriate for identifying patients with osteoporosis in the absence of a screening policy?

<p>Case-finding strategy (A)</p> Signup and view all the answers

What was the observed reduction in hip fractures due to the screening program using FRAX compared to standard clinical care?

<p>28% (C)</p> Signup and view all the answers

Apart from BMD, what should trigger fracture risk assessment according to Table 4?

<p>Thoracic kyphosis and height loss (D)</p> Signup and view all the answers

Which group of individuals was targeted for osteoporosis drug treatment using FRAX in the UK trial?

<p>Postmenopausal women with high hip fracture risk (B)</p> Signup and view all the answers

What condition can trigger fracture risk assessment, but is not accommodated in FRAX and should be assessed separately?

<p>(Excess) thyroid hormone treatment (A)</p> Signup and view all the answers

What type of fractures are considered major along with hip fractures?

<p>Spine, forearm, and shoulder fractures (C)</p> Signup and view all the answers

Who can be assessed using the FRAX tool?

<p>Postmenopausal women or men above age 50 with low bone density (C)</p> Signup and view all the answers

What information is required for the FRAX score calculator?

<p>Habits such as alcohol intake and disorders linked to osteoporosis (B)</p> Signup and view all the answers

What does a T-score in a bone density test indicate?

<p>Comparison of bone density to a healthy adult (D)</p> Signup and view all the answers

When may a doctor recommend treatment based on FRAX scores?

<p>If the FRAX score is 3% or more for hip fracture (D)</p> Signup and view all the answers

What do critics say about the accuracy of the FRAX tool?

<p>It underestimates the fracture risk in people who are at increased risk for falling (C)</p> Signup and view all the answers

What type of test is used to measure bone strength in the hip and spine?

<p>Bone density test (C)</p> Signup and view all the answers

In which group of individuals can the FRAX tool be used?

<p>Postmenopausal women or men above age 50 with low bone density (B)</p> Signup and view all the answers

What does a low T-score in a bone density test indicate?

<p>'Osteoporosis' compared to a healthy adult (D)</p> Signup and view all the answers

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