Lecture 12

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Questions and Answers

Which classification system for osteomyelitis is the most important and widely used in clinical trials?

No classification system is widely used

Cierny and Mader Classification

Waldvogel Classification (correct)

Cierny-Mader Classification

What is the most common form of osteomyelitis in pediatric age?

Contiguous spread from soft-tissue or joint infection

Hematogenous seeding from remote source (correct)

Chronic osteomyelitis

Direct inoculation from penetrating trauma or surgery

In which type of osteomyelitis is sluggish metaphyseal capillaries a common etiology?

Type IV: diffuse osteomyelitis

Type III: localized osteomyelitis

Type II: superficial osteomyelitis

Type I: medullary osteomyelitis (correct)

What is the duration of symptoms for subacute osteomyelitis according to the text?

More than two weeks, but less than six weeks Signup and view all the answers

Which type of osteomyelitis is typical in males during childhood and adolescence?

Acute hematogenous osteomyelitis Signup and view all the answers

How does the pyogenic organism reach the bone in acute hematogenous osteomyelitis?

Through the bloodstream from a known focus of infection Signup and view all the answers

What is a common feature of inflammation indices in acute hematogenous osteomyelitis?

Elevation Signup and view all the answers

How many tissue samples are typically required for biopsy and culture in osteomyelitis?

At least three Signup and view all the answers

What does imaging for osteomyelitis include?

Radiography, computed tomography, magnetic resonance imaging, and nuclear medicine Signup and view all the answers

What is the predominant basis for the treatment of acute osteomyelitis?

Antibiotic therapy Signup and view all the answers

What may be necessary for extensive bone involvement in chronic forms of osteomyelitis?

Complete removal and reconstructive techniques Signup and view all the answers

What percentage of prosthetic joint infections have negative cultures?

Up to 15% Signup and view all the answers

What are the surgical options for managing prosthetic joint infections?

Debridement and retention of prosthesis, resection arthroplasty with reimplantation, resection arthroplasty with no reimplantation, or amputation Signup and view all the answers

What is a risk factor for prosthetic joint infections?

Surgical factors and patient characteristics Signup and view all the answers

What does the treatment of prosthetic joint infections involve?

Surgery and antimicrobial therapy Signup and view all the answers

What is a potential surgical intervention for prosthetic joint infections?

Amputation Signup and view all the answers

Study Notes

Osteomyelitis: Diagnosis and Microbiology

Acute hematogenous osteomyelitis is typical in males during childhood and adolescence
The pyogenic organism reaches the bone through the bloodstream from a known focus of infection
Diagnosis involves clinical presentation, laboratory tests, biopsy, and imaging
In acute hematogenous osteomyelitis, inflammation indices are often elevated
At least three tissue samples are required for biopsy and culture
Microbiology varies based on age, type of osteomyelitis, and location
Imaging includes radiography, computed tomography, magnetic resonance imaging, and nuclear medicine
Treatment of acute osteomyelitis is predominantly based on antibiotic therapy

Osteomyelitis: Chronic Forms and Treatment Strategies

Chronic forms of osteomyelitis may require surgical intervention
Extensive bone involvement may necessitate complete removal and reconstructive techniques
Treatment involves sequestrectomy, debridement, and appropriate antibiotics

Prosthetic Joint Infections: Burden and Risk Factors

Prosthetic joint infection is a serious complication of prosthetic joint implantation
~2% of total procedures (~150,000/year in Italy) are affected
Cultures are negative in up to 15% of cases
Risk factors include surgical factors and patient characteristics

Prosthetic Joint Infections: Diagnosis and Treatment

Management consists of surgery and antimicrobial therapy
Surgical options include debridement and retention of prosthesis, resection arthroplasty with reimplantation, resection arthroplasty with no reimplantation, or amputation

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Description

Test your knowledge of osteomyelitis and prosthetic joint infections with this quiz. Explore the diagnosis, microbiology, chronic forms, treatment strategies, burden, risk factors, and management of these bone and joint infections.

Lecture 12 - Bone and Joint Infections

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