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Questions and Answers
What is a common adverse effect of tramadol?
What is a common adverse effect of tramadol?
Which of the following is a strongly recommended treatment for intra-articular therapy in osteoarthritis?
Which of the following is a strongly recommended treatment for intra-articular therapy in osteoarthritis?
Which condition may make opioid analgesics the preferred option for pain management in osteoarthritis?
Which condition may make opioid analgesics the preferred option for pain management in osteoarthritis?
What role does glucosamine play in osteoarthritis treatment?
What role does glucosamine play in osteoarthritis treatment?
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How often should a single joint generally be treated with glucocorticoids in intra-articular therapy?
How often should a single joint generally be treated with glucocorticoids in intra-articular therapy?
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What is a characteristic of capsaicin as a topical agent?
What is a characteristic of capsaicin as a topical agent?
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Why is the use of glucosamine not recommended by guidelines despite its popularity?
Why is the use of glucosamine not recommended by guidelines despite its popularity?
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Which of the following treatments is least likely to be effective for acute pain in osteoarthritis?
Which of the following treatments is least likely to be effective for acute pain in osteoarthritis?
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What is a characteristic feature of osteoarthritis pain?
What is a characteristic feature of osteoarthritis pain?
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Which joint symptoms are most commonly associated with osteoarthritis?
Which joint symptoms are most commonly associated with osteoarthritis?
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Which of the following is NOT a recognized risk factor for developing osteoarthritis?
Which of the following is NOT a recognized risk factor for developing osteoarthritis?
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Which of the following nonpharmacologic strategies is commonly used in the management of osteoarthritis?
Which of the following nonpharmacologic strategies is commonly used in the management of osteoarthritis?
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In osteoarthritis, which statement best describes the nature of joint involvement?
In osteoarthritis, which statement best describes the nature of joint involvement?
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How does osteoarthritis differ from rheumatoid arthritis in terms of morning stiffness?
How does osteoarthritis differ from rheumatoid arthritis in terms of morning stiffness?
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What is a potential adverse effect of using duloxetine for osteoarthritis management?
What is a potential adverse effect of using duloxetine for osteoarthritis management?
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Which method is NOT a pharmacologic management option commonly used for osteoarthritis?
Which method is NOT a pharmacologic management option commonly used for osteoarthritis?
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Which of the following statements about acetaminophen is true?
Which of the following statements about acetaminophen is true?
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What is the primary purpose of using NSAIDs in the pharmacologic management of osteoarthritis?
What is the primary purpose of using NSAIDs in the pharmacologic management of osteoarthritis?
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What typically remains normal in patients with osteoarthritis despite joint pain and dysfunction?
What typically remains normal in patients with osteoarthritis despite joint pain and dysfunction?
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Which of the following is a preferred option for patients at high risk for gastrointestinal complications when managing osteoarthritis?
Which of the following is a preferred option for patients at high risk for gastrointestinal complications when managing osteoarthritis?
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Why are topical NSAIDs not recommended for deeper joints like the hip?
Why are topical NSAIDs not recommended for deeper joints like the hip?
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What is the role of tramadol in the pharmacologic management of osteoarthritis?
What is the role of tramadol in the pharmacologic management of osteoarthritis?
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What type of exercise is generally advisable for patients with knee or hip osteoarthritis?
What type of exercise is generally advisable for patients with knee or hip osteoarthritis?
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Which of the following actions may be beneficial for patients experiencing osteoarthritis symptoms?
Which of the following actions may be beneficial for patients experiencing osteoarthritis symptoms?
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Study Notes
Osteoarthritis - Definition
- A degenerative disorder of the articular cartilage
- Associated with hypertrophic changes in the bone
- The "Wear and Tear" form of arthritis
- Strongly related to age
Osteoarthritis - Pathogenesis
- Progressive loss of joint cartilage
- Subchondral damage
- Joint space narrowing
- Changes in underlying bone and soft tissue
- Culminates in deformed, painful joints
Osteoarthritis - Classification
- Primary: Predominant form occurring in the absence of known precipitating event
- Secondary: Developmental disorders or inflammatory, metabolic or endocrine diseases
Osteoarthritis - Risk Factors
- Increased age
- Female sex
- Genetic predisposition
- Heavy physical activity
- Obesity increases load-bearing stress on hip and knee joints
Osteoarthritis - Clinical Presentation
- Joint pain, often worse with activity
- "Gelling phenomenon": pain worsens after a period of rest
- Morning stiffness, usually less than 30 minutes
- Joint locking or instability
- Loss of function, limiting activities of daily living
- Most common joints affected: hands, knees, hips, and spine
- Asymmetric, may affect one side more severely
- Erythrocyte sedimentation rate and C-reactive protein levels are typically normal
Osteoarthritis - Nonpharmacologic Management
- Primary strategy for treatment
- Pharmacologic management has significant adverse effects and modest efficacy
- Education, exercise, weight loss, and cognitive behavioral intervention are integral components.
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Description
Test your knowledge on osteoarthritis, a degenerative joint disorder. This quiz covers its definition, pathogenesis, classification, risk factors, and clinical presentation. Perfect for students and professionals interested in musculoskeletal health.