OS 230: Pharmacology Toxicity Notes
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Questions and Answers

What is the mechanism of action of minocycline?

  • Binds to calcium and iron (correct)
  • Deposits in teeth
  • Stains skin during long-term use
  • Inhibits COX-2

    • Which drug is known to cause staining of the skin with prolonged use?

  • Opioids
  • Cocaine
  • Tetracycline (correct)
  • Aspirin

    • What effect do oral contraceptives have on endometrial and ovarian cancers?

  • Decrease in endometrial and ovarian cancers (correct)
  • Inducing endometrial and ovarian cancers
  • Increase in endometrial and ovarian cancers
  • No effect on endometrial and ovarian cancers

    • Which condition can occur due to chronic aspirin toxicity?

    <p>Prolonged bleeding</p> Signup and view all the answers

    What is the main effect of COX-1 inhibition by nonselective NSAIDs like aspirin?

    <p>Prolonged bleeding</p> Signup and view all the answers

    What can happen when ammonia passes the blood-brain barrier due to aspirin ingestion?

    <p>Encephalopathy</p> Signup and view all the answers

    Which type of injury results in complete epithelium loss?

    <p>Abrasion</p> Signup and view all the answers

    'Saddle nose' deformity can result from the abuse of which substance?

    <p>Cocaine</p> Signup and view all the answers

    What is the main cause of a puncture wound?

    <p>A long and narrow object</p> Signup and view all the answers

    Which cells are more susceptible to radiation damage?

    <p>Cells with open chromatin</p> Signup and view all the answers

    Which vitamin is essential for proper blood clotting?

    <p>Vitamin K</p> Signup and view all the answers

    What is a potential side effect of taking warfarin, a vitamin K antagonist?

    <p>Prolonged bleeding</p> Signup and view all the answers

    Which vitamin deficiency is common in alcoholics?

    <p>Vitamin B1 (thiamine)</p> Signup and view all the answers

    What is a potential consequence of iodine deficiency?

    <p>Goiter</p> Signup and view all the answers

    What is the body mass index (BMI) cutoff for obesity?

    <p>BMI ≥ 30</p> Signup and view all the answers

    Which hormone is secreted from adipocytes to suppress appetite?

    <p>Leptin</p> Signup and view all the answers

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