OS 230: Pharmacology Toxicity Notes

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What is the mechanism of action of minocycline?

Binds to calcium and iron (correct)

Deposits in teeth

Stains skin during long-term use

Inhibits COX-2

Which drug is known to cause staining of the skin with prolonged use?

Opioids

Cocaine

Tetracycline (correct)

Aspirin

What effect do oral contraceptives have on endometrial and ovarian cancers?

Decrease in endometrial and ovarian cancers (correct)

Inducing endometrial and ovarian cancers

Increase in endometrial and ovarian cancers

No effect on endometrial and ovarian cancers

Which condition can occur due to chronic aspirin toxicity?

Prolonged bleeding Signup and view all the answers

What is the main effect of COX-1 inhibition by nonselective NSAIDs like aspirin?

Prolonged bleeding Signup and view all the answers

What can happen when ammonia passes the blood-brain barrier due to aspirin ingestion?

Encephalopathy Signup and view all the answers

Which type of injury results in complete epithelium loss?

Abrasion Signup and view all the answers

'Saddle nose' deformity can result from the abuse of which substance?

Cocaine Signup and view all the answers

What is the main cause of a puncture wound?

A long and narrow object Signup and view all the answers

Which cells are more susceptible to radiation damage?

Cells with open chromatin Signup and view all the answers

Which vitamin is essential for proper blood clotting?

Vitamin K Signup and view all the answers

What is a potential side effect of taking warfarin, a vitamin K antagonist?

Prolonged bleeding Signup and view all the answers

Which vitamin deficiency is common in alcoholics?

Vitamin B1 (thiamine) Signup and view all the answers

What is a potential consequence of iodine deficiency?

Goiter Signup and view all the answers

What is the body mass index (BMI) cutoff for obesity?

BMI ≥ 30 Signup and view all the answers

Which hormone is secreted from adipocytes to suppress appetite?

Leptin Signup and view all the answers

OS 230: Pharmacology Toxicity Notes

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Questions and Answers

What is the mechanism of action of minocycline?

Which drug is known to cause staining of the skin with prolonged use?

What effect do oral contraceptives have on endometrial and ovarian cancers?

Which condition can occur due to chronic aspirin toxicity?

What is the main effect of COX-1 inhibition by nonselective NSAIDs like aspirin?

What can happen when ammonia passes the blood-brain barrier due to aspirin ingestion?

Which type of injury results in complete epithelium loss?

'Saddle nose' deformity can result from the abuse of which substance?

What is the main cause of a puncture wound?

Which cells are more susceptible to radiation damage?

Which vitamin is essential for proper blood clotting?

What is a potential side effect of taking warfarin, a vitamin K antagonist?

Which vitamin deficiency is common in alcoholics?

What is a potential consequence of iodine deficiency?

What is the body mass index (BMI) cutoff for obesity?

Which hormone is secreted from adipocytes to suppress appetite?

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