40 Questions
What is a characteristic feature of traumatic ulcers?
Yellowish-grey floor of fibrin slough
What is the main concern when a traumatic ulcer fails to heal?
Malignancy
What is the typical age range for the characteristic presentation of eosinophilic ulcers?
Infants in the first year of life
What is a distinctive feature of eosinophilic ulcers?
Failure to heal and persistence for many months
What can eosinophilic ulcers mimic histopathologically?
Lymphoma
What triggers a more rapid resolution of eosinophilic ulcers?
Biopsy
What is the typical size of eosinophilic ulcers?
Exceeding 10 mm in diameter
What is a possible cause of eosinophilic ulcers?
Trauma
What is a characteristic of the fibrin slough that covers most oral ulcers?
It has a characteristic appearance and can be easily distinguished
Which of the following is an example of a granulomatous disease that can cause oral ulcers?
Tuberculosis
What is the primary characteristic that distinguishes an ulcer from other types of lesions?
A break in the continuity of epithelium
Which of the following is NOT a type of oral ulceration that can occur without preceding vesiculation?
Herpes labialis
What is the name of the disease that is characterized by recurrent oral ulcers and genital ulcers?
Behçet's disease
Which of the following is a common cause of traumatic oral ulcers?
All of the above
What is the term for the study of the histopathological features of immunologically-mediated disorders of the oral mucosa?
Histopathology
Which of the following is an example of a vesiculobullous disease that can cause oral ulcers?
Pemphigus vulgaris
Which diagnostic method is primarily used for identifying pemphigus and pemphigoid?
Direct and indirect immunofluorescence
What is one of the main reasons to perform a biopsy for recurrent aphthous stomatitis?
To rule out carcinoma or viral infections
What characteristic of eosinophilic ulcers can be misleading in a diagnosis?
Often resembling carcinoma
In the context of histopathological education, what should students understand about tuberculosis?
Its histopathological aspects
What is a primary diagnostic approach for erythema multiforme?
Clinical presentation
Which diseases are associated with immunologically-mediated disorders of the oral mucosa?
Pemphigus, pemphigoid, and erythema multiforme
What additional reading is recommended for students studying traumatic oral ulceration?
Both A and B
Which of the following aspects are included when studying granulomatous disease of the oral tissues?
Histopathological features, clinical presentations, and treatments
Which stage of syphilis affects approximately 30% of untreated individuals?
Tertiary syphilis
What type of inflammation is characteristic of tertiary syphilis?
Granulomatous inflammation
Which histopathological feature is NOT associated with primary and secondary stages of oral syphilis?
Peripheral pseudoepitheliomatous hyperplasia
Which stain can be used to detect the organism causing syphilis?
Steiner stain
What is a common clinical feature of secondary syphilis?
Snail-track pattern mucous patches
Which feature is characteristic of tertiary stage oral syphilitic lesions?
Peripheral pseudoepitheliomatous hyperplasia
What occurs in tertiary syphilis affecting the palate?
Ulcers perforate into the nasal cavity
Which is an appropriate action if oral ulcers persist for more than 10 days?
Biopsy to exclude other diseases
What type of cells are essential in the destruction of surface epithelium in Recurrent Aphthous Stomatitis?
Cytotoxic T cells (CD8+)
Which cytokine is primarily involved in the inflammatory reaction in Recurrent Aphthous Stomatitis?
Tumor necrosis factor (TNF)
Which histopathological feature is consistent with traumatic ulcers?
Fibrinopurulent membrane with neutrophils
What is a major etiological factor in the pathogenesis of Recurrent Aphthous Stomatitis?
T cell mediated immunologic reaction
Why might a biopsy be performed in a case of major aphthae?
To exclude carcinoma
Which of the following is not a trigger for Recurrent Aphthous Stomatitis?
Bacterial infection
In eosinophilic ulcers, where does the inflammatory infiltrate extend to?
Deeper tissues
Which clinical variation of Recurrent Aphthous Stomatitis may require biopsy to exclude viral infection?
Herpetiform
This lecture covers the histopathological aspects of traumatic oral ulceration, infectious diseases, and immunologically-mediated disorders.
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