Oral Pathology Quiz

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Questions and Answers

What is the characteristic of the epithelium in pyogenic granuloma?

It is infiltrated with macrophages

It is ulcerated with a fibrinous exudate

It is generally thin and atrophic (correct)

It is hyperplastic and hyperkeratinized

What is the main component of the connective tissue mass in pyogenic granuloma?

Fibrous scar tissue

Granulation tissue (correct)

Delicate fibroblasts

Endothelium-lined vascular spaces

What is the presumed etiology of pyogenic granuloma?

Inflammatory cytokines

Autoimmune disorders

Trauma leading to microbial invasion (correct)

Hormonal shifts during pregnancy

What is the characteristic of the connective tissue in pyogenic granuloma?

It is delicate and vascular Signup and view all the answers

What is the characteristic of the pregnancy tumor?

It is a well-defined gingival mass Signup and view all the answers

What is the histological similarity between pyogenic granuloma and pregnancy tumor?

Both have a similar granulation tissue Signup and view all the answers

What is the most common mechanism leading to the development of a soft tissue tumor-like lesion in the oral cavity?

Reactive hyperplasia Signup and view all the answers

What is the result of chronic inflammation in the tissue site?

Formation of granuloma and fibrosis Signup and view all the answers

What is the role of inflammatory cytokines in chronic inflammation?

Contributing to the progression of tissue damage Signup and view all the answers

What is characteristic of the epithelium in tori?

Atrophic with no rete ridges Signup and view all the answers

What is the characteristic of chronic inflammation in terms of duration?

Slow onset and long duration Signup and view all the answers

What is a common predisposing factor for keratoacanthoma?

Sun exposure Signup and view all the answers

What is the result of epithelial atrophy in tumor-like lesions?

Color lighter than normal due to epithelial atrophy Signup and view all the answers

What type of bone is characteristic of tori?

Dense lamellar, cortical bone Signup and view all the answers

What is an example of a cause of chronic inflammation?

Failure to eliminate the agent causing acute inflammation Signup and view all the answers

What is a possible treatment for tori?

Surgical correction for repeated trauma or ulceration Signup and view all the answers

What is the histological characteristic of tori?

Small amount of fibrofatty marrow Signup and view all the answers

What is the cause of keratoacanthoma?

Unknown Signup and view all the answers

Study Notes

Tumor-like Lesions (Fibrous Overgrowths)

Definition: Any pathologic growth that projects above the normal contour of the oral surface

Pathophysiology

Different mechanisms lead to development of soft tissue tumor-like lesions in the oral cavity
Most common mechanism: Reactive hyperplasia due to inflammation

Inflammation

Part of the body's defense mechanism to recognize and remove harmful foreign stimuli
Acute inflammation: Rapid, severe, and short-term (e.g. acute pulpitis and acute periapical abscess)
Chronic inflammation: Slow, long-term, and prolonged (e.g. chronic pulpitis and chronic periapical abscess)

General Features

Submucosal and/or epithelial masses that may ulcerate when traumatized
Color ranges: Lighter than normal (due to collagen or keratinization), reddish (due to epithelial atrophy or abundance of vascularized granulation tissue), or bleeds easily due to ulceration and increased vascularity
Painless, as nerves do not proliferate with reactive tissue

Types of Tumor-like Lesions

1. Pyogenic granuloma
1. Peripheral fibroma and peripheral ossifying fibroma
1. Peripheral giant cell granuloma (PGCG)
1. Denture-induced fibrous hyperplasia (denture fissuratum)
1. Inflammatory papillary hyperplasia (palatal papillomatosis)
1. Fibro-epithelial polyp (leaf-like denture fibroma)
1. Generalized gingival hyperplasia (drug-induced) and fibromatosis
1. Tori and exostosis
1. Keratoacanthoma

Pyogenic Granuloma

Etiology: Trauma → pathway to non-specific microbial invasion → oral mucous membrane
Clinical: Elevated, smooth, lobulated, or warty mass, painless, soft, deep red or reddish purple, and easily hemorrhagic on slight touch
Histology: Epithelium (thin, atrophic, eroded, or ulcerated), connective tissue mass (granulation tissue, endothelium-lined vascular spaces, and budding endothelial cells)

Pregnancy Tumor

Etiology: Combination of dental plaque buildup, hormonal shifts, inadequate brushing, and poorly fitted fillings
Clinical: Well-defined gingival mass, appears at about the third month of pregnancy or slightly later
Histology: Similar to pyogenic granuloma

Tori and Exostosis

Clinical: Exostosis (bony outgrowth), tori (bony protuberance on the palate or mandible)
Histology: Dense lamellar, cortical bone with small amount of fibrofatty marrow
Treatment: Surgical correction if exposed to trauma repeatedly or if ulcerated, surgical excision for denture construction

Keratoacanthoma

Etiology: Unknown, but sun exposure is a common predisposing factor, virus-like intranuclear inclusions have been described in these lesions

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Description

Test your knowledge of oral pathology with this quiz covering various types of lesions, including pyogenic granuloma, generalized gingival hyperplasia, and keratoacanthoma. Learn about their etiology, clinical features, and more.