Oral Candidosis
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Questions and Answers

Which factor is not listed as a predisposing factor to candidal infection?

  • Diabetes mellitus
  • Stress (correct)
  • Malnutrition/malabsorption
  • Age
  • What is the normal presence of Candida albicans in healthy mouths attributed to?

  • Excessive saliva production
  • Symbiotic relationship with lactobacillus acidophilus (correct)
  • Poor oral hygiene
  • High sugar diet
  • What is the most common oral fungal infection in humans?

  • Candidiasis (correct)
  • Aspergillosis
  • Histoplasmosis
  • Cryptococcosis
  • What is the defined term for multiple diseases caused by the yeast fungus Candida?

    <p>Oral Candidiasis</p> Signup and view all the answers

    What percentage of healthy people carry the infection of Candida albicans without clinical manifestations?

    <p>90%</p> Signup and view all the answers

    What limits the proliferation of Candida albicans in the mouth?

    <p>Acid production by lactobacillus acidophilus</p> Signup and view all the answers

    In which group is the immune system not well developed, leading to a predisposition for candidal infection?

    <p>Newborn infants</p> Signup and view all the answers

    Which antifungal agent is available as a cream and oral gel under the brand Daktarin?

    <p>Miconazole</p> Signup and view all the answers

    Which antifungal agent is contraindicated in acute liver disease and pregnancy?

    <p>Ketoconazole</p> Signup and view all the answers

    Which antifungal agent is administered intravenously for deep and systemic candidosis?

    <p>Amphotericin</p> Signup and view all the answers

    Which antifungal agent is used with caution with anticoagulant, antiepileptic, and antidiabetic medications?

    <p>Fluconazole</p> Signup and view all the answers

    Which antifungal agent is effective in angular stomatitis and should be taken 2 hours after antacids?

    <p>Ketoconazole</p> Signup and view all the answers

    Which antifungal agent acts by forming holes in the fungal cell membranes causing cell lysis?

    <p>Nystatin</p> Signup and view all the answers

    Which antifungal agent is available as 200 mg tablet and as a cream?

    <p>Ketoconazole</p> Signup and view all the answers

    Which antifungal agent is used for superficial, deep, and systemic mycosis?

    <p>Fluconazole</p> Signup and view all the answers

    Which antifungal agent is to be sucked four times a day or applied as a 3% ointment several times a day?

    <p>Nystatin</p> Signup and view all the answers

    Which factor can lead to secondary candida infection due to decreased salivary IgA?

    <p>Xerostomia</p> Signup and view all the answers

    Which condition can cause oral candidiasis by decreasing neutrophil function and blood flow?

    <p>Diabetes mellitus</p> Signup and view all the answers

    Which drug type can lead to oral candidiasis?

    <p>Contraceptive pills</p> Signup and view all the answers

    Which form of candidosis is most frequently encountered, typically affecting infants, immunocompromised adults, and older individuals?

    <p>Acute pseudomembranous</p> Signup and view all the answers

    Which condition can lead to postoperative oral candidiasis?

    <p>Lack of oral hygiene</p> Signup and view all the answers

    Which factor can decrease lymphocytes and phagocytic activity, leading to oral candidiasis?

    <p>Malnutrition and malabsorption</p> Signup and view all the answers

    Which disease can lead to oral candidiasis due to the effect of cytotoxic drugs on the immune system?

    <p>Leukemia</p> Signup and view all the answers

    What is a potential cause of angular cheilitis?

    <p>Nutritional deficiencies</p> Signup and view all the answers

    Which antifungal treatment is recommended for mixed or recurrent infections of angular cheilitis?

    <p>Miconazole gel</p> Signup and view all the answers

    What is a characteristic symptom of median rhomboid glossitis?

    <p>Pink rhomboid area lacking lingual papillae</p> Signup and view all the answers

    Why is systemic therapy considered for symptomatic median rhomboid glossitis?

    <p>Topical antifungal therapy is ineffective</p> Signup and view all the answers

    What is chronic hyperplastic candidosis associated with?

    <p>Heavy smoking in middle-aged men</p> Signup and view all the answers

    What characterizes chronic mucocutaneous candidosis (CMCC)?

    <p>Recurrent Candida infections due to impaired cell-mediated immunity</p> Signup and view all the answers

    Which antifungal drug is mentioned as part of the treatment for oral candidosis?

    <p>Fluconazole</p> Signup and view all the answers

    Study Notes

    Oral Candidosis: Types, Etiology, and Treatment

    • Angular cheilitis is caused by reduced vertical face height due to old dentures, severe attrition of natural dentition, nutritional deficiencies, oral dryness, or drooling.
    • Topical antifungal treatment for angular cheilitis includes nystatin or amphotericin suspension and cream, while miconazole gel is used for mixed or recurrent infections.
    • Median rhomboid glossitis is a symptomless, pink rhomboid area lacking lingual papillae, associated with immunosuppression, corticosteroid inhalers, tobacco use, dry mouth, or diabetes.
    • Systemic therapy is considered for symptomatic median rhomboid glossitis, as topical antifungal therapy is ineffective.
    • Chronic hyperplastic candidosis, potentially malignant, presents as a thick, white plaque with rough surface and is associated with heavy smoking in middle-aged men.
    • Chronic mucocutaneous candidosis (CMCC) is characterized by recurrent Candida infections due to impaired cell-mediated immunity and can be caused by thymic aplasia, endocrinopathies, or defective cell-mediated immunity.
    • CMCC types include familial, diffuse candidal granuloma, candidosis endocrinopathy syndrome, late-onset CMCC, and CMCC associated with primary immunodeficiency or HIV infection.
    • CMCC treatment includes imidazole antifungal drugs, but it responds poorly to topical treatment and rapidly reappears after discontinuation.
    • Rare systemic fungal infections of the mouth include aspergillosis, histoplasmosis, blastomycosis, cryptococcosis, paracoccidioidomycosis, and mucormycosis.
    • The diagnosis of candidosis involves a case history, clinical examination, bacterial smear and culture, candidal antibody titer, and biopsy for candidal leukoplakia.
    • Treatment of oral candidosis includes eliminating predisposing factors, using topical or systemic antifungal agents, and adjusting the duration of treatment based on the type of candidosis.
    • Antifungal agents for oral candidosis include nystatin, amphotericin, imidazole antifungal agents (miconazole, ketoconazole, fluconazole, itraconazole), and chlorhexidine. Nystatin can be administered as a suspension or pastille.

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    Description

    Test your knowledge of oral candidosis with this quiz covering types, etiology, and treatment. Learn about conditions such as angular cheilitis, median rhomboid glossitis, chronic hyperplastic candidosis, and chronic mucocutaneous candidosis, as well as their causes and treatment options.

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