Opium
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Questions and Answers

What is opium?

  • A drug that affects mood or behavior and is consumed for non-medical purposes.
  • A mixture of alkaloids related to morphine.
  • A naturally occurring opioid derived from opium.
  • An extract of the juice of the poppy Papaver somniferum. (correct)
  • What is an opioid?

  • A naturally occurring opioid derived from opium.
  • A naturally occurring, semi-synthetic, or synthetic compound. (correct)
  • A drug that affects mood or behavior and is consumed for non-medical purposes.
  • An extract of the juice of the poppy Papaver somniferum.
  • What is an opiate?

  • A mixture of alkaloids related to morphine.
  • Any naturally occurring opioid derived from opium (e.g. morphine). (correct)
  • A drug that affects mood or behavior and is consumed for non-medical purposes.
  • An extract of the juice of the poppy Papaver somniferum.
  • What is the mechanism of action of opioids?

    <p>They bind to specific receptors located throughout the central nervous system and other tissues.</p> Signup and view all the answers

    How many major types of opioid receptors have been identified?

    <p>Three</p> Signup and view all the answers

    Which part of the central nervous system has high concentrations of opioid receptors?

    <p>Peri-aqueductal grey area (PAG)</p> Signup and view all the answers

    Where are peripheral opioid receptors found?

    <p>All of the above</p> Signup and view all the answers

    Which opioid receptor is responsible for central interpretation of pain?

    <p>Mu-1</p> Signup and view all the answers

    Which opioid receptor is responsible for respiratory depression and physical dependence?

    <p>Mu-2</p> Signup and view all the answers

    Which opioid receptor is associated with analgesia, dysphoria, delusions, and hallucinations?

    <p>Delta</p> Signup and view all the answers

    Which opioid receptor is not considered as an opiate receptor?

    <p>σ-receptor</p> Signup and view all the answers

    Which opioid receptor is responsible for central excitation and can cause tachycardia, hypertension, and hallucinations?

    <p>σ-receptor</p> Signup and view all the answers

    Which endogenous opioid peptides activate μ, κ, and δ-receptors?

    <p>All of the above</p> Signup and view all the answers

    Which endogenous opioid peptides are widely distributed throughout the central nervous system (CNS)?

    <p>All of the above</p> Signup and view all the answers

    What is the main function of endogenous opioid peptides in the CNS?

    <p>Both neurotransmitters and modulators of response</p> Signup and view all the answers

    True or false: Traditional classification of opioids is based on their origin?

    <p>False</p> Signup and view all the answers

    True or false: Pure agonists have both affinity and efficacy for binding to opioid receptors?

    <p>True</p> Signup and view all the answers

    True or false: Partial agonists have a high intrinsic activity (efficacy) at opioid receptors?

    <p>False</p> Signup and view all the answers

    True or false: Mixed agonist-antagonists produce an agonist effect at one receptor and an antagonist effect at another?

    <p>True</p> Signup and view all the answers

    True or false: Pure antagonists have affinity for binding but no efficacy, and they block the action of both endogenous and exogenous ligands?

    <p>True</p> Signup and view all the answers

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