Opium

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Questions and Answers

What is opium?

  • A drug that affects mood or behavior and is consumed for non-medical purposes.
  • A mixture of alkaloids related to morphine.
  • A naturally occurring opioid derived from opium.
  • An extract of the juice of the poppy Papaver somniferum. (correct)

What is an opioid?

  • A naturally occurring opioid derived from opium.
  • A naturally occurring, semi-synthetic, or synthetic compound. (correct)
  • A drug that affects mood or behavior and is consumed for non-medical purposes.
  • An extract of the juice of the poppy Papaver somniferum.

What is an opiate?

  • A mixture of alkaloids related to morphine.
  • Any naturally occurring opioid derived from opium (e.g. morphine). (correct)
  • A drug that affects mood or behavior and is consumed for non-medical purposes.
  • An extract of the juice of the poppy Papaver somniferum.

What is the mechanism of action of opioids?

<p>They bind to specific receptors located throughout the central nervous system and other tissues. (D)</p> Signup and view all the answers

How many major types of opioid receptors have been identified?

<p>Three (B)</p> Signup and view all the answers

Which part of the central nervous system has high concentrations of opioid receptors?

<p>Peri-aqueductal grey area (PAG) (B)</p> Signup and view all the answers

Where are peripheral opioid receptors found?

<p>All of the above (D)</p> Signup and view all the answers

Which opioid receptor is responsible for central interpretation of pain?

<p>Mu-1 (B)</p> Signup and view all the answers

Which opioid receptor is responsible for respiratory depression and physical dependence?

<p>Mu-2 (C)</p> Signup and view all the answers

Which opioid receptor is associated with analgesia, dysphoria, delusions, and hallucinations?

<p>Delta (B)</p> Signup and view all the answers

Which opioid receptor is not considered as an opiate receptor?

<p>σ-receptor (D)</p> Signup and view all the answers

Which opioid receptor is responsible for central excitation and can cause tachycardia, hypertension, and hallucinations?

<p>σ-receptor (D)</p> Signup and view all the answers

Which endogenous opioid peptides activate μ, κ, and δ-receptors?

<p>All of the above (D)</p> Signup and view all the answers

Which endogenous opioid peptides are widely distributed throughout the central nervous system (CNS)?

<p>All of the above (D)</p> Signup and view all the answers

What is the main function of endogenous opioid peptides in the CNS?

<p>Both neurotransmitters and modulators of response (C)</p> Signup and view all the answers

True or false: Traditional classification of opioids is based on their origin?

<p>False (B)</p> Signup and view all the answers

True or false: Pure agonists have both affinity and efficacy for binding to opioid receptors?

<p>True (A)</p> Signup and view all the answers

True or false: Partial agonists have a high intrinsic activity (efficacy) at opioid receptors?

<p>False (B)</p> Signup and view all the answers

True or false: Mixed agonist-antagonists produce an agonist effect at one receptor and an antagonist effect at another?

<p>True (A)</p> Signup and view all the answers

True or false: Pure antagonists have affinity for binding but no efficacy, and they block the action of both endogenous and exogenous ligands?

<p>True (A)</p> Signup and view all the answers

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