Questions and Answers
What is the characteristic of Buprenorphine in terms of its opioid receptor interaction?
partial/weak μ agonist + κ antagonist
Which opioid receptor is associated with dysphoria?
κ (kappa) receptor
What is the characteristic of Nalorphine in terms of its opioid receptor interaction?
agonist - antagonist
What is the effect of Opioids on gastrointestinal motility?
Signup and view all the answers
What is the characteristic of Naltrexone in terms of its opioid receptor interaction?
Signup and view all the answers
What is the effect of Opioids on pupils?
Signup and view all the answers
What is the primary mechanism by which naloxone reverses the effects of opioid agonists?
Signup and view all the answers
What is the primary advantage of buprenorphine over morphine in terms of dependence?
Signup and view all the answers
What is characteristic of the withdrawal syndrome associated with buprenorphine?
Signup and view all the answers
What is the primary reason why naloxone is unable to precipitate withdrawal in buprenorphine-dependent subjects?
Signup and view all the answers
What is the primary mechanism by which buprenorphine exhibits its agonistic action?
Signup and view all the answers
What is the primary reason why buprenorphine is often preferred over morphine in clinical practice?
Signup and view all the answers
What is the specific antidote for acute morphine poisoning?
Signup and view all the answers
What is a characteristic of cross-tolerance among opioids?
Signup and view all the answers
What is a common adverse effect of morphine, especially in elderly males?
Signup and view all the answers
What is the primary cause of death in acute morphine poisoning?
Signup and view all the answers
What is the dose of morphine that can produce serious toxicity in a non-tolerant adult when administered intramuscularly?
Signup and view all the answers
What is the purpose of gastric lavage with pot.permanganate in the treatment of acute morphine poisoning?
Signup and view all the answers
What is the major advantage of tramadol over morphine?
Signup and view all the answers
What is the primary mechanism of action of tramadol?
Signup and view all the answers
What is a common side effect of tramadol?
Signup and view all the answers
What is the primary indication for opioid analgesics in dentistry?
Signup and view all the answers
What is the therapeutic benefit of administering morphine promptly in myocardial infarction?
Signup and view all the answers
What is the dose of tramadol for children?
Signup and view all the answers
What is the primary concern with the use of morphine that limits its medical application?
Signup and view all the answers
What is the primary symptom of morphine withdrawal in dependent subjects?
Signup and view all the answers
What is the primary method of treating morphine dependence?
Signup and view all the answers
What is a critical precaution when using morphine in certain patients?
Signup and view all the answers
What is a potential complication of morphine use in patients with bronchial asthma?
Signup and view all the answers
What is a contraindication for the use of morphine?
Signup and view all the answers
What is a consequence of retaining CO2 in patients with head injury when administered morphine?
Signup and view all the answers
Which patient group is more susceptible to urinary retention when administered morphine?
Signup and view all the answers
What is the potency of codeine compared to morphine?
Signup and view all the answers
What is the effect of codeine on cough?
Signup and view all the answers
What is the duration of action of a single oral dose of codeine?
Signup and view all the answers
What is the association between phenothiazines and tricyclic antidepressants with morphine?
Signup and view all the answers
What is the characteristic of codeine in terms of its analgesic effect?
Signup and view all the answers
What is the effect of morphine on respiratory function in patients with head injury?
Signup and view all the answers
Which patient group is more sensitive to morphine?
Signup and view all the answers
What is the association between morphine and vomiting in patients with head injury?
Signup and view all the answers