4 Questions
What do Peripherally-acting mu-opioid receptor antagonists (PAMORAS) do?
Block opioid receptors in the gut to reduce constipation without affecting analgesia.
When are PAMORAS indicated?
Opioid-Induced Constipation (OIC) when constipation is due to opioid use.
What do peripherally-acting mu-opioid receptor antagonists (PAMORAS) do?
Block opioid receptors in the gut to reduce constipation without affecting analgesia.
PAMORAS are only effective when constipation is secondary to the use of an _____.
opioid
Study Notes
Treatment of Opioid-Induced Constipation (OIC)
- Peripherally-acting mu-opioid receptor antagonists (PAMORAS) are used to treat OIC.
- PAMORAS work by blocking opioid receptors in the gut to reduce constipation.
- PAMORAS do not affect analgesia, which means they do not reduce the pain-relieving effects of opioids.
- PAMORAS are only effective when constipation is caused by the use of opioids.
Drug Dosing and Safety
- PAMORAS have specific dosing regimens.
- Patients taking PAMORAS must be monitored for side effects and safety.
- The safety and side effects of PAMORAS vary depending on the specific drug used.
Treatment of Opioid-Induced Constipation (OIC)
- Peripherally-acting mu-opioid receptor antagonists (PAMORAS) are used to treat OIC.
- PAMORAS work by blocking opioid receptors in the gut to reduce constipation.
- PAMORAS do not affect analgesia, which means they do not reduce the pain-relieving effects of opioids.
- PAMORAS are only effective when constipation is caused by the use of opioids.
Drug Dosing and Safety
- PAMORAS have specific dosing regimens.
- Patients taking PAMORAS must be monitored for side effects and safety.
- The safety and side effects of PAMORAS vary depending on the specific drug used.
Learn about treatment options for opioid-induced constipation, including peripherally-acting mu-opioid receptor antagonists (PAMORAS) that reduce constipation without affecting analgesia.
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