Opioid Analgesics and Receptors
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Questions and Answers

Which opioid receptor has the highest affinity for morphine?

  • mu (m) receptors (correct)
  • kappa (k) receptors
  • All opioid receptors have equal affinity for morphine
  • delta (d) receptors

    • What type of pain is typically managed with opioid analgesics?

  • Moderate to severe pain (correct)
  • Menstrual cramps and sports injuries
  • Osteoarthritis and ankylosing spondylitis
  • Mild headaches and fever

    • Which of the following is TRUE about the opioid antagonist Naloxone?

  • It produces physical dependence
  • It inhibits all opioid receptors, with the highest affinity for mu receptors (correct)
  • It activates all opioid receptors
  • It has no effect on opioid receptors

    • What is the primary mechanism of action for non-opioid analgesics?

    <p>Inhibition of prostaglandin synthesis</p> Signup and view all the answers

    Which non-opioid analgesic is a centrally acting agent?

    <p>Tramadol</p> Signup and view all the answers

    What is the primary use of non-opioid analgesics?

    <p>Control of mild to moderate pain and/or fever</p> Signup and view all the answers

    Which enzyme is required for prostaglandin formation and is inactivated by aspirin, NSAIDs, and acetaminophen?

    <p>Cyclooxygenase</p> Signup and view all the answers

    What is the primary difference in the effect of activating kappa receptors versus mu receptors?

    <p>Activation of kappa receptors does not produce as much physical dependence as activation of mu receptors</p> Signup and view all the answers

    What type of pain is typically associated with the use of opioid analgesics?

    <p>Postoperative pain and bone break pain</p> Signup and view all the answers

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