Opioid Analgesics and Receptors
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Questions and Answers

Which opioid receptor has the highest affinity for morphine?

  • mu (m) receptors (correct)
  • kappa (k) receptors
  • All opioid receptors have equal affinity for morphine
  • delta (d) receptors

What type of pain is typically managed with opioid analgesics?

  • Moderate to severe pain (correct)
  • Menstrual cramps and sports injuries
  • Osteoarthritis and ankylosing spondylitis
  • Mild headaches and fever

Which of the following is TRUE about the opioid antagonist Naloxone?

  • It produces physical dependence
  • It inhibits all opioid receptors, with the highest affinity for mu receptors (correct)
  • It activates all opioid receptors
  • It has no effect on opioid receptors

What is the primary mechanism of action for non-opioid analgesics?

<p>Inhibition of prostaglandin synthesis (B)</p> Signup and view all the answers

Which non-opioid analgesic is a centrally acting agent?

<p>Tramadol (B)</p> Signup and view all the answers

What is the primary use of non-opioid analgesics?

<p>Control of mild to moderate pain and/or fever (D)</p> Signup and view all the answers

Which enzyme is required for prostaglandin formation and is inactivated by aspirin, NSAIDs, and acetaminophen?

<p>Cyclooxygenase (D)</p> Signup and view all the answers

What is the primary difference in the effect of activating kappa receptors versus mu receptors?

<p>Activation of kappa receptors does not produce as much physical dependence as activation of mu receptors (A)</p> Signup and view all the answers

What type of pain is typically associated with the use of opioid analgesics?

<p>Postoperative pain and bone break pain (A)</p> Signup and view all the answers

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