Opioid Agonists and Antagonists Quiz

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Questions and Answers

Which alkaloid is naturally occurring and is a substitution of a methyl group for a hydroxyl group on carbon 3 of the morphine molecule?

  • Codeine (correct)
  • Heroin
  • Morphine
  • Hydromorphone

What is the chemical modification in heroin compared to morphine?

  • Substitution of a methyl group for a hydroxyl group on carbon 3
  • Carbonyl group instead of hydroxyl at carbon 6 and lacks double bond between 7 and 8
  • Substitution of an acetyl group on carbon 3 and 6 (correct)
  • Contains phenantrene nucleus of morphine but is manufactured by synthesis

Which class of opioids is widely used to supplement general anesthesia or as a primary anesthetic in very high doses?

  • Semisynthetic opioids
  • Synthetic opioids (correct)
  • Morphine derivatives
  • Opium alkaloids

What is the unique characteristic of opioids in producing analgesia?

<p>Analgesia without loss of touch, proprioception, or consciousness (C)</p> Signup and view all the answers

What is the composition of the three rings of phenanthrene in opium alkaloids?

<p>Composed of 14 carbon atoms (A)</p> Signup and view all the answers

Flashcards

Codeine

Naturally occurring alkaloid with a methyl group substituted for a hydroxyl group on carbon 3 of morphine.

Heroin's Chemical Modification

Morphine with acetyl groups substituted on carbons 3 and 6.

Synthetic Opioids

A class of opioids used as a supplement to general anesthesia or as a primary anesthetic at high doses.

Opioid Analgesia

Reduced pain sensation without affecting touch, proprioception, or consciousness.

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Phenanthrene Rings

Opium alkaloids contain three rings of phenanthrene, these rings consist of 14 carbon atoms.

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