Oncology and Lymphatic System Disorders
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Questions and Answers

What is the most common type of hemangioma?

  • Capillary hemangioma (correct)
  • Cavernous hemangioma
  • Juvenile hemangioma
  • Mixed hemangioma

    • What is the characteristic of hereditary hemorrhagic telangiectasia?

  • It is a benign tumor that only occurs in the skin and oral mucous membranes
  • It is a malignant tumor composed of blood-filled vessels
  • It is an autosomal dominant disorder with mutations in genes encoding TGF-β signaling pathway components (correct)
  • It is a type of hemangioma that always regresses spontaneously

    • What is a characteristic of juvenile hemangiomas?

  • They are found only in the liver and spleen
  • They are extremely common and can be multiple (correct)
  • They always undergo malignant transformation
  • They are extremely rare and always occur internally

    • What can occur due to the rupture of hereditary hemorrhagic telangiectasia lesions?

    <p>Serious epistaxis (nosebleed), gastrointestinal bleeding, or hematuria</p> Signup and view all the answers

    What percentage of benign tumors of infancy and childhood are hemangiomas?

    <p>7%</p> Signup and view all the answers

    What is the location of nearly one third of internal hemangiomas?

    <p>Liver</p> Signup and view all the answers

    What is a common consequence of chronic edema in lymphedema?

    <p>Deposition of ECM and fibrosis</p> Signup and view all the answers

    What is the term for the milky accumulation of lymph in the abdominal space?

    <p>Chylous ascites</p> Signup and view all the answers

    What is the characteristic of benign vascular tumors?

    <p>Composed of vascular channels filled with blood cells or lymph lined by a monolayer of normal-appearing ECs</p> Signup and view all the answers

    What is the term for the tumor-like lesions that can present diagnostic challenges?

    <p>Congenital or developmental malformations and non-neoplastic reactive vascular proliferations</p> Signup and view all the answers

    What is the most common type of benign vascular neoplasm?

    <p>Benign hemangiomas</p> Signup and view all the answers

    What is the characteristic of malignant vascular tumors?

    <p>Highly aggressive and invasive</p> Signup and view all the answers

    Where are Bacillary Angiomatosis lesions most commonly found?

    <p>In the distal portion of the digits</p> Signup and view all the answers

    What is the treatment for Bacillary Angiomatosis?

    <p>Antibiotic treatment</p> Signup and view all the answers

    What is the role of HIF1α in Bacillary Angiomatosis?

    <p>It drives VEGF production and vascular proliferation</p> Signup and view all the answers

    What is the vector of transmission for Bartonella quintana?

    <p>Human body lice</p> Signup and view all the answers

    What is Kaposi sarcoma used as a criterion for the diagnosis of?

    <p>AIDS</p> Signup and view all the answers

    What is the characteristic of the epithelioid ECs in Bacillary Angiomatosis?

    <p>They exhibit nuclear atypia and mitoses</p> Signup and view all the answers

    What is the possible origin of a tumor in instances where it arises from lymphatic vessels?

    <p>Lymphangiosarcoma</p> Signup and view all the answers

    What is a common finding in advanced skin angiosarcoma lesions?

    <p>Necrosis and hemorrhage</p> Signup and view all the answers

    What is a characteristic of poorly differentiated skin angiosarcoma tumors?

    <p>EC origin can be demonstrated by staining for CD31 and von Willebrand factor</p> Signup and view all the answers

    What is a possible cause of hepatic angiosarcomas?

    <p>Certain carcinogens, including arsenical pesticides and polyvinyl chloride</p> Signup and view all the answers

    What is the typical timeframe between exposure and subsequent tumor development in cases of angiosarcoma?

    <p>Years</p> Signup and view all the answers

    What can occur when certain neoplasms grow within veins?

    <p>Marked lower-extremity edema</p> Signup and view all the answers

    What is a characteristic of lymphangitis?

    <p>Red, painful subcutaneous streaks</p> Signup and view all the answers

    What is a cause of secondary or obstructive lymphedema?

    <p>Tumors involving lymphatic channels or regional lymph nodes</p> Signup and view all the answers

    What can cause bacteremia or sepsis?

    <p>Uncontained bacteria in lymph nodes</p> Signup and view all the answers

    What is a type of primary lymphedema?

    <p>Familial Milroy disease</p> Signup and view all the answers

    What can be a result of postradiation fibrosis?

    <p>Secondary or obstructive lymphedema</p> Signup and view all the answers

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