Omeprazole (PriLOSEC) Flashcards
11 Questions
100 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the generic name of PriLOSEC?

  • omeprazole (correct)
  • lansoprazole
  • pantoprazole
  • rabeprazole

What is the therapeutic classification of omeprazole?

antiulcer agent

What is the pharmacologic classification of omeprazole?

proton-pump inhibitor

What are the primary indications for omeprazole?

<p>GERD or maintenance of healing in erosive esophagitis, duodenal ulcers, short-term treatment of active benign gastric ulcer, OTC: heartburn occurring more than 2x weekly</p> Signup and view all the answers

What is one of the actions of omeprazole?

<p>Binds to an enzyme on gastric parietal cells in the presence of gastric acidic pH, preventing the final transport of hydrogen ions into the gastric lumen</p> Signup and view all the answers

What therapeutic effect does omeprazole have?

<p>Diminished accumulation of acid in the gastric lumen with lessened gastroesophageal reflux, healing of duodenal ulcer</p> Signup and view all the answers

Lab tests may indicate an increase in ___ and ___ levels due to omeprazole.

<p>AST, ALT</p> Signup and view all the answers

What are some adverse reactions associated with omeprazole?

<p>C-DIFF associated diarrhea (life threatening), abdominal pain (most common)</p> Signup and view all the answers

What are the contraindications for using omeprazole?

<p>Hypersensitivity, discontinue in breastfeeding; use cautiously in liver disease, high dose usage for a year or more increases risk of hip, wrist, and spine fractures, use for more than 3 yrs increases risk of B12 deficiency</p> Signup and view all the answers

What nursing implications should be assessed for a patient taking omeprazole?

<p>Assess for occult blood, emesis, and gastric aspirate; monitor bowel function for signs of C-DIFF</p> Signup and view all the answers

What client teaching should be provided for omeprazole?

<p>May cause occasional drowsiness or dizziness; notify HCP of medications and avoid irritants; report severe symptoms to HCP.</p> Signup and view all the answers

Study Notes

Omeprazole (PriLOSEC) Overview

  • Generic name: omeprazole
  • Trade name: PriLOSEC
  • Classification: antiulcer agent (therapeutic); proton-pump inhibitor (pharmacologic)

Indications

  • Used for Gastroesophageal Reflux Disease (GERD) and for maintaining healing in erosive esophagitis
  • Addresses duodenal ulcers and provides short-term treatment for active benign gastric ulcers
  • Available OTC for heartburn occurring more than twice weekly

Mechanism of Action

  • Binds to an enzyme on gastric parietal cells at acidic pH
  • Prevents transport of hydrogen ions into the gastric lumen, reducing acid accumulation

Therapeutic Effects

  • Decreased acid levels in the gastric lumen
  • Reduction in gastroesophageal reflux
  • Promotes healing of duodenal ulcers

Laboratory Tests

  • Regular monitoring of CBC with differential, liver enzymes (AST, ALT, alkaline phosphatase, bilirubin)
  • Monitor INR and PT time in patients on warfarin
  • Watch for hypomagnesemia
  • Serum gastrin concentration may rise in initial weeks of treatment

Adverse Reactions

  • Gastrointestinal risks include life-threatening C. Difficile Associated Diarrhea (CDAD)
  • Common side effect: abdominal pain

Contraindications

  • Avoid in patients with hypersensitivity to omeprazole
  • Discontinue use in breastfeeding women
  • Caution advised in patients with liver disease
  • Long-term use (over one year) may heighten risk of hip, wrist, and spine fractures
  • Extended use (over three years) increases risk of vitamin B12 deficiency

Nursing Implications

  • Assess for signs of gastrointestinal bleeding (occult blood, emesis)
  • Monitor bowel function closely; report diarrhea, cramping, fever, or bloody stools as they may indicate CDAD

Client Teaching

  • Inform patients that drug may cause drowsiness or dizziness
  • Advise to notify healthcare provider of all medications, vitamins, or supplements, especially St. John's Wort
  • Recommend avoidance of alcohol, aspirin, NSAIDs, and irritating foods
  • Instruct patients to report any black, tarry stool, diarrhea, abdominal pain, or persistent headaches, especially if stools contain blood, pus, or mucus
  • Advise against self-treating diarrhea due to potential severity

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Description

Test your knowledge on Omeprazole, also known as PriLOSEC, through these flashcards. Learn about its generic name, therapeutic classification, pharmacologic classification, and indications for use. This interactive quiz is perfect for students in pharmacology or healthcare fields.

More Like This

Proton Pump Inhibitors Quiz
14 questions

Proton Pump Inhibitors Quiz

SubstantiveMandolin avatar
SubstantiveMandolin
Proton Pump Inhibitors and Acid Secretion Quiz
16 questions
Omeprazole (Prilosec) Flashcards
9 questions

Omeprazole (Prilosec) Flashcards

SensationalChrysoprase468 avatar
SensationalChrysoprase468
Pharmacology: Omeprazole Flashcards
11 questions
Use Quizgecko on...
Browser
Browser