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Questions and Answers
What role does cAMP play in the olfactory process?
What role does cAMP play in the olfactory process?
- It mediates the opening of cation channels. (correct)
- It directly binds to odorants.
- It functions as an odorant receptor.
- It activates sodium-potassium pumps.
Which sequence accurately describes the activation of olfactory receptors?
Which sequence accurately describes the activation of olfactory receptors?
- Odorants bind → block cAMP → close cation channels
- Odorants are synthesized → bind to receptors → open Na+ channels
- Odorants bind → activate Golf → increase cAMP (correct)
- Odorants bind → activate Golf → decrease cAMP
What effect does the opening of cAMP-gated cation channels have on the olfactory cells?
What effect does the opening of cAMP-gated cation channels have on the olfactory cells?
- It hyperpolarizes the cell membrane.
- It triggers exocytosis of odorants.
- It initiates the synthesis of G-proteins.
- It depolarizes the cell membrane. (correct)
What initiates the signaling process in olfaction?
What initiates the signaling process in olfaction?
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What happens after the activation of Golf in olfactory cells?
What happens after the activation of Golf in olfactory cells?
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Study Notes
Olfaction Process
- Odorants interact with specialized odorant receptors, which are G-protein-coupled receptors on the cell membrane.
- Binding of odorants activates the G-protein called Golf.
- Activation of Golf leads to an increase in cyclic AMP (cAMP) levels within the cell.
- Elevated cAMP opens cation channels that are gated by cAMP, allowing positive ions to flow into the cell.
- The influx of positive ions causes depolarization of the olfactory receptor cell.
- Depolarization generates an electrical signal that travels along the axon to the olfactory bulb, indicating the presence of a scent.
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