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Questions and Answers
What is the primary consideration for selecting an ointment base for a dry skin condition like psoriasis?
What is the primary consideration for selecting an ointment base for a dry skin condition like psoriasis?
- The effect of the drug on the viscosity of the ointment base
- The ability of the ointment to occlude the site and retain moisture (correct)
- The desired release rate of the drug substance from the ointment base
- The desire for easy removal of the base by washing with water
What factor is crucial for drug release from the ointment base?
What factor is crucial for drug release from the ointment base?
- Particle size and shape of the therapeutic agent
- Solubility of the therapeutic agent within the formulation (correct)
- Chemical composition of the ointment base
- Viscosity of the ointment base
Which type of formulation may lead to drug degradation and shortened shelf-life for a hydrolyzable therapeutic agent?
Which type of formulation may lead to drug degradation and shortened shelf-life for a hydrolyzable therapeutic agent?
- Hydrophobic ointment bases
- Occlusive ointment bases
- Water-based formulations
- O/W creams (correct)
What is the primary factor determining the effect of the drug on the viscosity of the ointment base?
What is the primary factor determining the effect of the drug on the viscosity of the ointment base?
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What factor is important when there is a desire for occlusion of moisture from the skin?
What factor is important when there is a desire for occlusion of moisture from the skin?
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