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Questions and Answers
What is the primary purpose of rectus muscle recession and resection surgery in the context of nystagmus?
What is the primary purpose of rectus muscle recession and resection surgery in the context of nystagmus?
Which of the following is a complication associated with subretinal fluid drainage for retinal detachment?
Which of the following is a complication associated with subretinal fluid drainage for retinal detachment?
What is the main indication for performing pars plana vitrectomy (PPV) in retinal detachment surgery?
What is the main indication for performing pars plana vitrectomy (PPV) in retinal detachment surgery?
What materials are commonly used as tamponading agents in retinal detachment surgery?
What materials are commonly used as tamponading agents in retinal detachment surgery?
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What is the mechanism by which scleral buckling helps treat retinal detachment?
What is the mechanism by which scleral buckling helps treat retinal detachment?
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What is a notable contraindication for using alpha 2 agonists?
What is a notable contraindication for using alpha 2 agonists?
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Which side effect is commonly associated with the use of miotics?
Which side effect is commonly associated with the use of miotics?
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How do carbonic anhydrase inhibitors function in the treatment of ocular conditions?
How do carbonic anhydrase inhibitors function in the treatment of ocular conditions?
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What is a precaution when prescribing alpha 2 agonists to young patients?
What is a precaution when prescribing alpha 2 agonists to young patients?
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Which example is classified as a carbonic anhydrase inhibitor?
Which example is classified as a carbonic anhydrase inhibitor?
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What is the primary indication for performing a laser iridotomy?
What is the primary indication for performing a laser iridotomy?
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Which medication is the first choice for managing elevated intraocular pressure (IOP) after laser iridotomy?
Which medication is the first choice for managing elevated intraocular pressure (IOP) after laser iridotomy?
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What technique involves delivering laser to the trabecular meshwork to enhance aqueous outflow?
What technique involves delivering laser to the trabecular meshwork to enhance aqueous outflow?
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Which side effect is associated with the use of prostaglandin analogues?
Which side effect is associated with the use of prostaglandin analogues?
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What is the mechanism of action of beta blockers in glaucoma management?
What is the mechanism of action of beta blockers in glaucoma management?
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What is a major advantage of selective laser trabeculoplasty (SLT) over traditional treatments?
What is a major advantage of selective laser trabeculoplasty (SLT) over traditional treatments?
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Which statement accurately describes acetazolamide in the context of lowering IOP?
Which statement accurately describes acetazolamide in the context of lowering IOP?
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What is the typical IOP reduction achieved by prostaglandin analogues?
What is the typical IOP reduction achieved by prostaglandin analogues?
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What is the maximum visual acuity (VA) observable for a patient with presenting VA at the level of perception of light (PL)?
What is the maximum visual acuity (VA) observable for a patient with presenting VA at the level of perception of light (PL)?
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Which condition requires emergency referral following a post-operative examination?
Which condition requires emergency referral following a post-operative examination?
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How does photodynamic therapy (PDT) with verteporfin primarily work?
How does photodynamic therapy (PDT) with verteporfin primarily work?
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What role do anti-VEGF drugs play in the treatment of wet AMD?
What role do anti-VEGF drugs play in the treatment of wet AMD?
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What is a significant side effect of argon green laser treatment for maculopathy?
What is a significant side effect of argon green laser treatment for maculopathy?
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For which patient group does NICE recommend anti-VEGF treatment?
For which patient group does NICE recommend anti-VEGF treatment?
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What is a potential complication following pan-retinal photocoagulation (PRP) treatment for severe non-proliferative retinopathy?
What is a potential complication following pan-retinal photocoagulation (PRP) treatment for severe non-proliferative retinopathy?
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In which circumstance might a patient with wet AMD be considered for off-label anti-VEGF treatment?
In which circumstance might a patient with wet AMD be considered for off-label anti-VEGF treatment?
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What is one of the primary complications associated with retinal detachment (RD) surgery?
What is one of the primary complications associated with retinal detachment (RD) surgery?
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Which device is not part of the standard vitrectomy setup?
Which device is not part of the standard vitrectomy setup?
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What is the primary purpose of injecting a gas bubble during pneumatic retinopexy?
What is the primary purpose of injecting a gas bubble during pneumatic retinopexy?
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Which step is involved in the cataract surgery process of capsulorhexis?
Which step is involved in the cataract surgery process of capsulorhexis?
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What complication can arise from posterior capsule rupture (PCR) during cataract surgery?
What complication can arise from posterior capsule rupture (PCR) during cataract surgery?
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Which of the following is a symptom of post-operative endophthalmitis?
Which of the following is a symptom of post-operative endophthalmitis?
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During cataract surgery, what is the purpose of hydrosealing?
During cataract surgery, what is the purpose of hydrosealing?
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What type of cataract surgery involves the use of a cryoprobe?
What type of cataract surgery involves the use of a cryoprobe?
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What is a common post-operative instruction for patients who have undergone cataract surgery?
What is a common post-operative instruction for patients who have undergone cataract surgery?
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Which of the following is NOT a type of cataract surgery mentioned?
Which of the following is NOT a type of cataract surgery mentioned?
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Study Notes
Nystagmus
- Surgery on all four recti muscles can be used to center the null zone
- Face turn to the right, null zone to left
- Surgery moves BE's in the direction of CHP to centre the null zone
- RLR 8mm resection, RMR 5mm recession, LMR 6mm resection, LLR 7mm recession
- May improve vision but may not abolish CHP
- Effect may not last
- Most patients will not reach driving standard
Subretinal Fluid Drainage
- Drainage of fluid via the sclera for deep or longstanding SRF
- Not done frequently due to complications
- Complications include retinal perforation, incarceration in the entry site
RD Surgery - Pars Plana Vitrectomy
- When: Giant tears, very large breaks, or PVR (where scleral buckling unlikely to work)
- Cut and aspirate vitreous
- Infusion of saline to maintain the vitreous cavity pressure and volume
- Tamponading agents: expanding gases or silicone oil
- Complications: Raised IOP, cataracts, band keratopathy
RD Surgery - Scleral Buckling
- Silicone sutured onto the sclera, creating an inwards indentation
- Closes RD by apposing RPE to sensory retina
- Complications; Transient IOP spikes & diplopia, CMO, buckle extrusion/intrusion/infection
RD Surgery - Vitrectomy and Retinopexy
- Vitrectomy: 3 ports - infusion cannula, vitreous cutter, and fibreoptic light probe
- Remove the central vitreous gel and posterior hyaloid face
- Pneumatic retinopexy for small breaks
- Inject a gas bubble
- Use laser/cryo to seal breaks
Cataract Surgery - Phacoemulsification
- Anaesthesia, povidone-iodine 5% or chlorhexidine instillation and eyelid cleaning
- Draping and speculum insertion
- Creation of 1-2 side ports and the main corneal incision
- Viscoelastic into the AC
- Capsulorhexis: femto laser, cystotome, forceps
- Hydrodissection: insert fluid under capsulorhexis to separate lens from capsule
- Divide and conquer/phaco chop
- Removal of lens cortex: vacuum carefully peels away from capsule and aspirated
- IOL insertion
- Wound sealing: hydrosealing, stepped approach
- Prophylactic Abx intracamerally/subconjunctivally
- Femtosecond lasers: more precise with slightly improved refractive outcomes, but costly, difficult to learn, time-consuming
Other Types of Cataract Surgery
- Extracapsular cataract extraction (ECCE): large anterior capsulotomy with large limbal incision
- Intracapsular cataract extraction (ICCE): cryoprobe removes entire lens and capsule
- Manual small-incision cataract surgery (MSICS) - used for high volume clinics in developing countries
Cataract Surgery - Intra-Operative Complications
- Damage to the iris or cornea
- Corneal epithelial abrasion, endothelial damage, Descemet's tear, iris damage
- Damage to the capsule - posterior capsule rupture (PCR)
- Loss of all or part of the cataract or the implant into the back of the eye
- Bleed (suprachoroidal haemorrhage) - ruptured posterior ciliary artery
- Endophthalmitis
Cataract Surgery - Post Op Review
- Instil all post-op drops as specified (Abx and steroids)
- Avoid: rubbing/touching eye, dusty/dirty environments, no water or soap in the eye, no swimming, no bending for heavy objects, no eye makeup
- Can resume light exercise and everyday activities within 2-3/7
- Mild discomfort is normal
- May get diplopia initially
- Is vision what they expect it to be?
- Unexplained reduced vision?
- Was there a guarded prognosis?
- Do they need listing for the second eye?
- Symptomatic cataract?
- VA \6/12?
Cataract Surgery - Post Operative Endophthalmitis
- Severe inflammation that can lead to total loss of vision
- Symptoms: painful red eye and significant loss of vision
- Signs: lid oedema and chemosis, significant conj hyperaemia, corneal haze, AC activity, vitritis
- Differentials: retained lens material, vitreous haem, severe p/o uveitis
- Management: sample aqueous and vitreous for culture, IV + systemic Abx, topical and systemic steroids, pars plana vitrectomy
- Prognosis: depends on VA at presentation
- If PL 1/3 may achieve up to 6/12, if better than PL then up to 2/3 may achieve this
How Soon to Refer Post-Op Complications
- Emergency: suspected endophthalmitis
- Urgent: retinal detachment/retinal tear, wound closure problems, marked or persistent mild/moderate iritis, IOP>28mmHg, unexpected IOL displacement +/- refractive surprise, corneal oedema, cystoid macular oedema, severe diabetic retinopathy, drop allergy
- Routine: significant symptomatic PCO, patient not happy with vision/refractive outcome/comfort
Photodynamic Therapy (PDT)
- PDT with verteporfin has largely been replaced by anti VEGF
- PDT may also be used for chronic central serous chorioretinopathy
- Intravenous injection of verteporfin (visudyne)
- Verteporfin preferentially taken up by the CNV membrane, not the retina, hence no retinal damage
- Drug is activated by low powered laser causing damage to proliferating cells and seals/regresses leaking vessels
Anti-VEGF
- Vascular endothelial growth factor (VEGF) is a protein that triggers the formation of new blood vessels
- Anti VEGF drugs bind with VEGF to prevent the trigger for abnormal blood vessel growth and leakage
- Anti VEGF drugs are administered via intravitreal injection
- NICE recommends for patients with: evidence of progressive wet AMD, VA between 6/12 and 6/96, no structural damage to the fovea
- Refer patients with suspected wet AMD regardless of their level of vision
- Patients with VA better than 6/12 or worse than 6/96 may be considered for treatment off license in certain clinical circumstances
- Most patients are suitable for anti VEGF ~ 90%
Maculopathy
- Argon green laser energy absorbed by and destroys micro-aneurysms
- Closes leakage site
- Encourages exudates absorption & oedema resolution
- May destroy surrounding area
- Poor response shown with ischaemic maculopathy
Non-proliferative
- Prevent progression to R3
- Laser Pan-Retinal Photocoagulation (PRP) - scatter pattern
- Reduce O2 demand of retina by tissue destruction, inhibits NV growth
- Regression
- Scarring & peripheral visual field loss
- Tritan colour vision defect
Laser Iridotomy
- Treatment of primary angle closure glaucoma (or secondary angle closure with pupil block)
- Laser used to create a small hole in the iris
- Patient should lie down
- Acetazolamide 500mg (IV if IOP >50mmHg, orally if IOP\ 24mmHg)
### Laser Trabeculoplasty
- Delivery of laser to the trabecular meshwork in order to increase aqueous outflow
- Examples: SLT, Argon laser trabeculoplasty, Micro pulse laser trabeculoplasty
- Usage: Primary and secondary open angle glaucoma, ocular hypertension
Selective Laser Trabeculoplasty
- First line treatment for Primary Open Angle Glaucoma and Ocular Hypertension
- Low energy light targeting melanin rich cells in the aqueous chamber
- This results in an immune response whereby white blood cells clear the affected cells and rebuild the trabecular meshwork
- Benefits: Reduced ocular and systemic side effects, no tissue damage, reduced need for medication
Prostaglandin Analogues
- Increases uveoscleral outflow.
- Examples: Latanoprost, Travoprost, Bimatoprost, Tafluprost
- Side effects: Skin (reversible) & iris (irreversible) hyperpigmentation
- Excessive eyelash growth
- Cystoid Macular Oedema
- Conjunctival hyperaemia
- Avoid in pregnancy
Beta Blockers
- Decrease Aqueous production
- Examples: Timolol, Betaxolol, Carteolol, Metripranolol
- Side effects: Ocular: allergy, punctate corneal erosions, reduced aqueous secretion, Decreased corneal sensitivity
- Systemic: Bradycardia, Arrhythmia, heart failure, Bronchospasm, Syncope, Nocturnal hypotension, Headache and depression
- Contraindications: Asthma, COPD, bradycardia, heart failure, Normal tension glaucoma
Alpha 2 Agonists
- Decreases aqueous production and increases u veo-scleral outflow
- Examples: Brimonidine, Apraclonidine
- Contraindications: Children under 2 years old, accompanying oral monoamine oxidase inhibitor antidepressants
- Note: As these drugs cross the blood-brain barrier and thus caution should be taken in young children who have central nervous system depression and hypotension
Carbonic Anhydrase Inhibitors
- Inhibit aqueous secretion
- Examples: Dorzolamide, Brinzolamide
- Side effects: Blurred vision, induced myopia
- Contraindications: sulphonamide allergy, renal impairment, take caution with individuals with corneal endothelial dysfunction
Miotics
- Contraction of the sphincter pupillae pulls the peripheral iris away from the trabecular meshwork thus opening the anterior chamber angle
- Contract the ciliary muscle - increasing aqueous outflow through the trabecular meshwork
- Example: Pilocarpine
- Side effects: brow ache, miosis, myopic shift, increase in cataract symptoms, confusion, bradycardia, bronchospasm, and gastrointestinal symptoms
- Systemic side effects are rare
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Description
Test your knowledge on various ocular surgical techniques such as nystagmus treatment, subretinal fluid drainage, and retinal detachment surgery. This quiz covers essential information including procedures, indications, and potential complications. Ideal for medical students and professionals in ophthalmology.