Podcast
Questions and Answers
What is the primary aim of exercise during pregnancy?
What is the primary aim of exercise during pregnancy?
To stay fit.
How can pelvic floor exercises affect women during and after pregnancy?
How can pelvic floor exercises affect women during and after pregnancy?
They may reduce the risk of urinary and fecal incontinence.
What are the recommended breastfeeding practices for infants in the first two years?
What are the recommended breastfeeding practices for infants in the first two years?
Start within an hour of birth, exclusively for the first 6 months, and continue up to 2 years.
What urine components are screened during antenatal urine tests?
What urine components are screened during antenatal urine tests?
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What is the benefit of assessing blood pressure during pregnancy?
What is the benefit of assessing blood pressure during pregnancy?
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What is the purpose of anti-D immunoglobulin prophylaxis in pregnant women?
What is the purpose of anti-D immunoglobulin prophylaxis in pregnant women?
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What screening is offered to pregnant women in the UK at their booking visit?
What screening is offered to pregnant women in the UK at their booking visit?
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What is the accuracy of ultrasound in estimating gestational age in the first trimester?
What is the accuracy of ultrasound in estimating gestational age in the first trimester?
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What are the signs of placental separation during delivery?
What are the signs of placental separation during delivery?
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Define 'presenting part' in the context of labor.
Define 'presenting part' in the context of labor.
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What does the term 'vertex' refer to in fetal presentation?
What does the term 'vertex' refer to in fetal presentation?
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How is 'station' defined in obstetrics?
How is 'station' defined in obstetrics?
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What is caput succedaneum and when is it typically observed?
What is caput succedaneum and when is it typically observed?
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What is the importance of engagement during delivery?
What is the importance of engagement during delivery?
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How does molding of the fetal skull occur during childbirth?
How does molding of the fetal skull occur during childbirth?
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What does the term 'dystocia' signify in labor?
What does the term 'dystocia' signify in labor?
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What are the three main factors that influence the progress of labor?
What are the three main factors that influence the progress of labor?
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What is considered an adequate strength of contractions measured by Montevideo units (MVU)?
What is considered an adequate strength of contractions measured by Montevideo units (MVU)?
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What are the four types of pelvis, and which one is considered normal?
What are the four types of pelvis, and which one is considered normal?
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What is the role of intrauterine pressure catheters (IUPC) during labor?
What is the role of intrauterine pressure catheters (IUPC) during labor?
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List two maternal conditions that may warrant consideration for preterm delivery.
List two maternal conditions that may warrant consideration for preterm delivery.
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What is the significance of assessing contraction frequency and duration during labor?
What is the significance of assessing contraction frequency and duration during labor?
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What are some contraindications for labor induction?
What are some contraindications for labor induction?
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What treatment options are available for managing inefficient uterine action during labor?
What treatment options are available for managing inefficient uterine action during labor?
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What is considered a prolonged deceleration in fetal heart rate monitoring?
What is considered a prolonged deceleration in fetal heart rate monitoring?
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What heart rate range denotes a reassuring overall impression in fetal monitoring?
What heart rate range denotes a reassuring overall impression in fetal monitoring?
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List two potential causes of fetal tachycardia.
List two potential causes of fetal tachycardia.
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What baseline variability indicates a non-reassuring fetal status?
What baseline variability indicates a non-reassuring fetal status?
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What complication can result from fetal heart rate bradycardia?
What complication can result from fetal heart rate bradycardia?
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What does a baseline heart rate over 180 bpm signify?
What does a baseline heart rate over 180 bpm signify?
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Name one risk factor associated with decreased baseline variability.
Name one risk factor associated with decreased baseline variability.
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What are two maternal conditions that can contribute to fetal compromise?
What are two maternal conditions that can contribute to fetal compromise?
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At what gestational age should uncomplicated monochorionic twin pregnancies be offered elective delivery?
At what gestational age should uncomplicated monochorionic twin pregnancies be offered elective delivery?
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What is the increased risk of continuing uncomplicated twin pregnancies beyond 38 weeks gestation?
What is the increased risk of continuing uncomplicated twin pregnancies beyond 38 weeks gestation?
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What causes Rh incompatibility in a pregnant woman?
What causes Rh incompatibility in a pregnant woman?
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Describe the clinical presentation of Rh isoimmunization.
Describe the clinical presentation of Rh isoimmunization.
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What is the procedure for preventing Rh incompatibility in unsensitized Rh-negative mothers?
What is the procedure for preventing Rh incompatibility in unsensitized Rh-negative mothers?
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What should be conducted during a pregnant woman's first visit regarding Rh compatibility?
What should be conducted during a pregnant woman's first visit regarding Rh compatibility?
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What are some situations in which Rh immunoprophylaxis is indicated?
What are some situations in which Rh immunoprophylaxis is indicated?
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How can the father’s Rh status influence the risk of Rh incompatibility for the fetus?
How can the father’s Rh status influence the risk of Rh incompatibility for the fetus?
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What is a potential long-term benefit of breastfeeding for children?
What is a potential long-term benefit of breastfeeding for children?
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Why is urine screening conducted during antenatal visits?
Why is urine screening conducted during antenatal visits?
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What are the implications of dating ultrasound for pregnancies with irregular cycles?
What are the implications of dating ultrasound for pregnancies with irregular cycles?
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What is the recommended timeframe for exclusive breastfeeding?
What is the recommended timeframe for exclusive breastfeeding?
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How is chronic hypertension managed during pregnancy?
How is chronic hypertension managed during pregnancy?
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What does the Family Origin Questionnaire (FOQ) screen for in pregnant women?
What does the Family Origin Questionnaire (FOQ) screen for in pregnant women?
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What defines normal vaginal delivery (NVD)?
What defines normal vaginal delivery (NVD)?
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What is the accuracy of ultrasound in estimating gestational age during the second trimester?
What is the accuracy of ultrasound in estimating gestational age during the second trimester?
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What does the term 'gravidity' refer to in obstetrics?
What does the term 'gravidity' refer to in obstetrics?
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At what gestational week does fetal quickening typically occur for a primigravida?
At what gestational week does fetal quickening typically occur for a primigravida?
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What are the two methods for administering anti-D immunoglobulin to Rh-negative mothers?
What are the two methods for administering anti-D immunoglobulin to Rh-negative mothers?
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What are the indications for performing a pelvic examination during pregnancy?
What are the indications for performing a pelvic examination during pregnancy?
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How does smoking affect fetal development?
How does smoking affect fetal development?
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What does 'multiparous' mean in terms of childbirth?
What does 'multiparous' mean in terms of childbirth?
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What is the significance of the term 'nullipara'?
What is the significance of the term 'nullipara'?
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Explain the effect of alcohol consumption during pregnancy.
Explain the effect of alcohol consumption during pregnancy.
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What is the average delivery time for triplets and quadruplets in terms of weeks?
What is the average delivery time for triplets and quadruplets in terms of weeks?
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How can polyhydramnios be managed to reduce the risk of preterm labor?
How can polyhydramnios be managed to reduce the risk of preterm labor?
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What are some potential outcomes of Mullerian anomalies in pregnant women?
What are some potential outcomes of Mullerian anomalies in pregnant women?
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What is the significance of testing for cervicovaginal fetal fibronectin in cases of threatened preterm labor?
What is the significance of testing for cervicovaginal fetal fibronectin in cases of threatened preterm labor?
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What are the potential risks of using indomethacin for managing preterm labor?
What are the potential risks of using indomethacin for managing preterm labor?
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Why is magnesium sulfate used in the context of preterm labor?
Why is magnesium sulfate used in the context of preterm labor?
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What are tocolytics and what is their purpose in managing preterm labor?
What are tocolytics and what is their purpose in managing preterm labor?
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What complications can arise from the use of beta-agonists in managing preterm labor?
What complications can arise from the use of beta-agonists in managing preterm labor?
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What are three methods to investigate the causes of fetal demise?
What are three methods to investigate the causes of fetal demise?
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List two conditions requiring a cesarean section in the case of fetal demise.
List two conditions requiring a cesarean section in the case of fetal demise.
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What are the risks associated with prolonged follow-up after fetal demise?
What are the risks associated with prolonged follow-up after fetal demise?
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How can one diagnose Intrauterine Growth Restriction (IUGR)?
How can one diagnose Intrauterine Growth Restriction (IUGR)?
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What psychological support measures are recommended after delivery in cases of fetal demise?
What psychological support measures are recommended after delivery in cases of fetal demise?
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What is the significance of the Spalding sign in examining a fetal demise?
What is the significance of the Spalding sign in examining a fetal demise?
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What are two long-term risks associated with neonates recovering from IUGR?
What are two long-term risks associated with neonates recovering from IUGR?
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Explain the relevance of serial biometry and liquor assessments in managing IUGR.
Explain the relevance of serial biometry and liquor assessments in managing IUGR.
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What conditions in women with systemic lupus erythematosus (SLE) increase their risk during pregnancy?
What conditions in women with systemic lupus erythematosus (SLE) increase their risk during pregnancy?
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How can lupus nephritis and preeclampsia be differentiated during pregnancy?
How can lupus nephritis and preeclampsia be differentiated during pregnancy?
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What is the recommended timing for conception post-renal transplant in women on immunosuppressive agents?
What is the recommended timing for conception post-renal transplant in women on immunosuppressive agents?
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What physiological changes occur in thyroid function during pregnancy?
What physiological changes occur in thyroid function during pregnancy?
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What is the most common cause of hypothyroidism in pregnancy?
What is the most common cause of hypothyroidism in pregnancy?
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What complications are associated with untreated hypothyroidism in pregnancy?
What complications are associated with untreated hypothyroidism in pregnancy?
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What is the protocol for managing newborns of mothers with high hepatitis B infectivity?
What is the protocol for managing newborns of mothers with high hepatitis B infectivity?
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What are the primary antihypertensive agents recommended during pregnancy?
What are the primary antihypertensive agents recommended during pregnancy?
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What is the difference between gravidity and parity in pregnancy terminology?
What is the difference between gravidity and parity in pregnancy terminology?
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Explain fetal quickening and its significance in pregnancy.
Explain fetal quickening and its significance in pregnancy.
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What are some indications and contraindications for pelvic examinations during pregnancy?
What are some indications and contraindications for pelvic examinations during pregnancy?
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Discuss the impacts of alcohol consumption during pregnancy.
Discuss the impacts of alcohol consumption during pregnancy.
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What characterizes a normal vaginal delivery (NVD) according to SSTVV?
What characterizes a normal vaginal delivery (NVD) according to SSTVV?
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Define the terms nulligravida and grand multipara in obstetrics.
Define the terms nulligravida and grand multipara in obstetrics.
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What effect does smoking have on fetal health during pregnancy?
What effect does smoking have on fetal health during pregnancy?
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At what point in gestation is the fetus typically evaluated for viability through ultrasound?
At what point in gestation is the fetus typically evaluated for viability through ultrasound?
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What is one immediate benefit of initiating breastfeeding within the first hour after birth?
What is one immediate benefit of initiating breastfeeding within the first hour after birth?
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Why is monitoring blood pressure crucial for pregnant women with chronic hypertension?
Why is monitoring blood pressure crucial for pregnant women with chronic hypertension?
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What is the significance of conducting a glucose tolerance test in women with a history of gestational diabetes?
What is the significance of conducting a glucose tolerance test in women with a history of gestational diabetes?
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What is the primary rationale for performing routine urine tests during antenatal care?
What is the primary rationale for performing routine urine tests during antenatal care?
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In what scenario might dating ultrasound provide greater benefits than relying solely on the last menstrual period (LMP)?
In what scenario might dating ultrasound provide greater benefits than relying solely on the last menstrual period (LMP)?
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How does the accuracy of ultrasound in determining gestational age change throughout pregnancy?
How does the accuracy of ultrasound in determining gestational age change throughout pregnancy?
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What role does antenatal anti-D immunoglobulin prophylaxis play for Rh-negative mothers?
What role does antenatal anti-D immunoglobulin prophylaxis play for Rh-negative mothers?
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What are the implications of screening for thalassaemia using the Family Origin Questionnaire?
What are the implications of screening for thalassaemia using the Family Origin Questionnaire?
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What is the distinguishing feature of a 'threatened' miscarriage compared to 'inevitable' miscarriage?
What is the distinguishing feature of a 'threatened' miscarriage compared to 'inevitable' miscarriage?
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In which situation might a therapeutic abortion be legally justified?
In which situation might a therapeutic abortion be legally justified?
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What clinical sign may indicate a missed miscarriage during a follow-up ultrasound?
What clinical sign may indicate a missed miscarriage during a follow-up ultrasound?
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What is a key management step for a patient diagnosed with a threatened miscarriage?
What is a key management step for a patient diagnosed with a threatened miscarriage?
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What differentiates 'incomplete' miscarriage from 'complete' miscarriage?
What differentiates 'incomplete' miscarriage from 'complete' miscarriage?
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What are the leading causes of maternal deaths in developing countries?
What are the leading causes of maternal deaths in developing countries?
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What symptoms characterize a septic miscarriage, and what may this condition lead to?
What symptoms characterize a septic miscarriage, and what may this condition lead to?
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What is the significance of serum β-hCG levels in monitoring a threatened miscarriage?
What is the significance of serum β-hCG levels in monitoring a threatened miscarriage?
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List two major causes of perinatal and neonatal mortality.
List two major causes of perinatal and neonatal mortality.
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How can a missed miscarriage be diagnosed during initial antenatal assessments?
How can a missed miscarriage be diagnosed during initial antenatal assessments?
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What is antepartum hemorrhage (APH), and what are its potential causes?
What is antepartum hemorrhage (APH), and what are its potential causes?
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Explain the classification of placenta previa based on its proximity to the internal os.
Explain the classification of placenta previa based on its proximity to the internal os.
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How does maternal age and parity relate to the risk of maternal death?
How does maternal age and parity relate to the risk of maternal death?
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Identify one fetal condition and one preterm condition that can lead to neonatal mortality.
Identify one fetal condition and one preterm condition that can lead to neonatal mortality.
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What impact does cervical erosion have in the context of antepartum hemorrhage?
What impact does cervical erosion have in the context of antepartum hemorrhage?
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Mention one risk factor for placenta previa and its relevance.
Mention one risk factor for placenta previa and its relevance.
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What is the normal hemoglobin (Hb) level during the 1st trimester of pregnancy?
What is the normal hemoglobin (Hb) level during the 1st trimester of pregnancy?
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What two most common factors cause anemia during pregnancy and puerperium?
What two most common factors cause anemia during pregnancy and puerperium?
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List two symptoms of iron deficiency anemia (IDA).
List two symptoms of iron deficiency anemia (IDA).
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What are the acceptable hemoglobin levels for postpartum women, immediately after and after puerperium?
What are the acceptable hemoglobin levels for postpartum women, immediately after and after puerperium?
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When should a pregnant patient ideally have a complete blood count (CBC) test done during gestation?
When should a pregnant patient ideally have a complete blood count (CBC) test done during gestation?
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What two management options are available for correcting iron deficiency anemia (IDA)?
What two management options are available for correcting iron deficiency anemia (IDA)?
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What is the indication for a blood transfusion concerning hemoglobin (Hb) levels during pregnancy?
What is the indication for a blood transfusion concerning hemoglobin (Hb) levels during pregnancy?
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What is the most effective form of contraception recommended during the postpartum period?
What is the most effective form of contraception recommended during the postpartum period?
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Study Notes
General Exercise Advice
- Aim of exercise: Staying fit during pregnancy
- Pelvic floor exercises: Help reduce urinary and fecal incontinence during pregnancy and after birth
Breastfeeding Advice
- Benefits:
- Protects against diarrhea and common childhood illnesses
- Reduces the risk of obesity later in life
- Associated with higher IQ in children
- Recommended Schedule:
- Start breastfeeding within one hour of birth
- Exclusive breastfeeding for the first six months
- Continue breastfeeding beyond six months, ideally up to two years
Antenatal Urine Tests
- Screening for:
- Protein: Detects renal disease or pre-eclampsia
- Persistent glycosuria: Detects pre-existing diabetes or gestational diabetes (GDM)
- Nitrites: Detects urinary tract infections
Blood Pressure Assessment
- Purpose: Detect unrecognized chronic hypertension
- Low-dose aspirin: Recommended for women with chronic hypertension to reduce pre-eclampsia and perinatal mortality
Antenatal Anti-D Immunoglobulin Prophylaxis
- Administration: Single large dose at 28 weeks or two doses at 28 and 34 weeks
GDM Follow-Up
- Women with previous GDM: Offered a glucose tolerance test or random blood glucose test in the first trimester
Thalassaemia Screening
- Offered to all pregnant women during the booking visit
- Screening method: Family Origin Questionnaire (FOQ) and/or FBC results
Dating Ultrasound (US)
- Purpose: Define gestational age (GA) and estimated delivery date (EDD)
- Accuracy:
- T1 (11+3 - 13+6 weeks): ± 1 week, based on crown-rump length (CRL)
- T2 (14 - 20 weeks): ± 2 weeks, based on head circumference (HC)
-
20 weeks: ± 3 weeks, based on femoral length (FL)
- Benefits:
- Accurate dating for irregular cycles or uncertain last menstrual period (LMP)
- Decreased incidence of induction of labor (IOL) for prolonged pregnancy
- Optimizes serum screening for fetal abnormalities
- Detection of multiple pregnancies and chorionicity
Placental Separation
- Signs:
- Apparent lengthening of the cord
- Small gush of blood from the placental bed
- Rising of uterine fundus above the umbilicus
- Uterine contraction resulting in a firm globular feel on palpation
Presentation and Lie
- Presenting part: The lower part of the fetus palpable on vaginal examination
- Vertex presentation: Normal presentation in cephalic presentation
- Mal-presentation: Any other presentation besides vertex, including breech, cord, brow, face, or compound presentation
- Lie: Relationship between the longitudinal axis of the fetus and the mother's uterus, described as longitudinal, oblique, or transverse
Station
- Level of descent of the presenting part during vaginal examination
- 0 station: When the lowest part of the presenting part reaches the ischial spine
- Measured in centimeters above or below the ischial spine
Engagement
- Widest diameter of the presenting part passing the pelvic brim
- Assessed on abdominal examination
Amniotomy
- Artificial rupture of membranes
- May occur after spontaneous labor or as part of labor augmentation
Attitude
- Relationship of different fetal parts to each other
- Usually flexion
Caput Succedaneum
- Edema over the presenting part of the head
- Common in prolonged labor
Moulding
- Change in fetal skull shape to adapt to the maternal pelvis during passage
- Sutures allow movement between bones, enabling parietal bones to slide over frontal and occipital bones
- Severe molding may indicate cephalo-pelvic disproportion (CPD)
Position
- Refers to the position of the fetal occiput in relation to the maternal pelvis
- Dominator: Occiput for cephalic presentation, mentum for face presentation, and sacrum for breech presentation
- OA (occipito-anterior): Considered "normal"
Abnormal Labour
- Synonyms: Abnormal, Prolonged, Obstructed, Difficult, Dysfunctional labour, Dystocia
- Characterized by:
- Poor progress in the first or second stage of labor
- Fetal compromise
- Malpresentation or malposition
- Uterine scar
- Induced or precipitate labor
- Indicates a problem in one of the "3 Ps":
- Power (uterine contractions)
- Passage (uterus, cervix, and bony pelvis)
- Passenger (fetus)
Power
- Inefficient Uterine Action: Common cause of poor labor progress, more frequent in primiparas and older women
- Characterized by: Weak and infrequent contractions
- Assessment:
- Subjective: History
- Objective:
- Examination (Palpation)
- External uterine tocography (Tocodynamometer): Measures frequency and duration of contractions
- Intrauterine pressure catheters (IUPC): Measures strength or pressure but rarely used
- Normal contractions: 4-5 contractions, with moderate strength (20-40 mmHg) and sufficient duration
- Montevideo Units (MVU)
- Measure collective peak strength of contractions (mmHg) over 10 minutes
- Adequate MVU: >200
- Optimal strength for cervical dilation: 50-60 mmHg
Treatment of Inefficient Uterine Action
- Rehydration
- Artificial rupture of membranes (ARM)
- Intravenous oxytocin (also treats irregular contractions in multiple pregnancies)
Passage
- Abnormal Pelvis: Only gynecoid is normal
- Pelvic types: Gynecoid, android, anthropoid, platypelloid
- Gynecoid: Normal type
- Other types: Can lead to obstructed labor
- Abnormal pelvis shape caused by: Rickets, osteomalacia, tuberculosis, tumors of bones, childhood poliomyelitis, previous accidents, developmental dysplasia of the hip (DDH), congenital deformity of the sacrum or coccyx, kyphosis, and scoliosis
- Contracted inlet: AP diameter < 41 cm, or twins greater than 38 weeks
Indications for Induction of Labor (IOL)
- Premature rupture of membranes (PROM) at term, or at 34-37 weeks with additional factors
- Hypertensive disorders, especially pre-eclampsia (PET)
- Intrauterine growth restriction (IUGR)
- Intrauterine fetal demise (IUFD) or history of IUFD
- Diabetes mellitus and macrosomia
- Deteriorating maternal illness
- Unexplained antepartum hemorrhage (APH)
- Cholestasis
- Maternal isoimmunization
- Social reasons
Contraindications for IOL
- Placenta previa
- Severe fetal compromise
- Deteriorating maternal condition with major APH
- PET or cardiac disease may favor Cesarean section (C/S)
- Breech presentation (relative contraindication)
- Previous C/S (inform patient about risk of uterine rupture)
- Preterm pregnancy is not an absolute contraindication
Methods for IOL
- Membrane sweep: Weekly from 40 weeks, excluding placenta previa
- Prostaglandin analogues
- Oxytocin
Fetal Distress
- Definition:
- Fetuses experience stress during labor due to uterine contractions reducing fetal perfusion.
- Pathological fetal distress: Significant reduction in fetal well-being
- Prolonged deceleration: Deceleration lasting longer than 2 minutes
- Non-reassuring: 2-3 minutes
- Abnormal: Longer than 3 minutes
- Overall impression: Based on assessment of all CTG aspects, categorized as reassuring, suspicious or abnormal
- Reassuring: Normal baseline heart rate, variability, and decelerations
- Non-reassuring: Abnormal baseline heart rate, variability, or decelerations, but not severe enough to be considered abnormal
- Abnormal: Severe abnormalities in baseline heart rate, variability, or decelerations
Causes of Fetal Compromise
- Placental insufficiency
- Placental abruption
- Uterine hyperstimulation
- Maternal hypotension
- Cord compression
Causes of Fetal Tachycardia (>160 bpm)
- Maternal fever
- Fetal hypoxia
- Fetal anemia
- Amnionitis
- Fetal tachyarrhythmia (supraventricular tachycardia, SVT, 200-240 bpm)
- Fetal heart failure
- Drugs (beta-sympathomimetic)
Causes of Fetal Bradycardia (< 110 bpm)
- Heart block (little or no variability)
- Occiput posterior or transverse position
- Serious fetal compromise
- Hypoxia
Causes of Decreased Baseline Variability
- Fetal metabolic acidosis
- Pre-existing neurologic abnormality
- CNS depressants
- Fetal sleep cycles
Causes of Preterm Labor (PTL)
- Chromosomal abnormalities (trisomies), congenital anomalies
- Infections: Including non-recurring E coli, Group B streptococcus (GBS), both of which can induce preterm labor
- Diabetes mellitus, extreme maternal age (over 40), obesity, obstetric cholestasis
- Nuchal cord, abnormal insertion of cord to placenta
- Thrombophilias: Increased risk of pre-eclampsia, IUGR
- Maternal BMI > 30
- Placental complications
- Obstetric cholestasis: Pruritis (itching) without rash after 24 weeks, plus abnormal liver function tests that improve after delivery
Time of Delivery
- Uncomplicated monochorionic twin pregnancies: Elective delivery at 36 weeks after a course of antenatal corticosteroids
- Dichorionic twin pregnancies: Delivery at 37 weeks
- Continuing uncomplicated twin pregnancies beyond 38 weeks: Increased risk of intrauterine fetal death
Rh Incompatibility and Hydrops
- Pathophysiology:
- Rh-negative mother exposed to Rh+ fetal blood (D antigen)
- Immune system perceives D antigen as foreign
- Production of anti-D antibodies
- Antibodies cross the placenta, bind to fetal erythrocytes, and cause hemolysis
- Clinical presentation of Rh isoimmunization:
- Varies from mild to severe hemolysis
- In utero: Bilirubin removed by placenta, fetal anemia, risk of heart failure (hydrops fetalis)
- After delivery: Varying degrees of anemia and hyperbilirubinemia, risk of kernicterus
Prevention of Rh Incompatibility
- Identify blood group and Rh status in the first antenatal visit:
- Rh+ mother: No concern
- Rh- mother: Assess partner's Rh status
- Rh- partner: No concern
- Rh+ partner: Potential for Rh+ fetus
- If mother is unsensitized (negative indirect Coombs test):
- Anti-D (Rh immunoglobulin) at 28-32 weeks or two low doses at 28 and 34 weeks
- If neonate is Rh+, administer another dose of anti-D to the mother within 72 hours of delivery (up to 9 days)
- Rh Ig immunoprophylaxis: Administered if there is a risk of feto-maternal hemorrhage:
- Early pregnancy bleeding (miscarriage, ectopic pregnancy, gestational trophoblastic disease)
- APH
- External cephalic version (ECV)
- Invasive procedures (chorionic villus sampling, CVS)
- Abdominal trauma
- For miscarriages: Give anti-D if GA is > 9-12 weeks. Even at 8 weeks if severe or recurrent bleeding occurs.
Pregnancy Terms
- Normal pregnancy delivery occurs between 37 and 42 weeks.
- Pre-term delivery occurs before 37 weeks.
- Pregnancy is typically calculated from the last menstrual period (LMP) which totals 40 weeks.
- From the point of conception, pregnancy is only 38 weeks.
Parity and Gravidity
- Gravidity refers to the number of pregnancies a woman has had regardless of the outcome.
- A woman is considered multigravida if she has been pregnant more than once.
- Parity refers to the number of deliveries after 24 weeks gestation, regardless of whether the baby was born alive or dead.
- Nullipara refers to a woman who has never carried a pregnancy beyond 24 weeks.
- Primipara refers to a woman who has given birth once before.
- Multiparous refers to a woman who has given birth more than once.
- Grand multipara refers to a woman who has given birth 3 or more times.
Fetal Development
- Fetal quickening refers to the first movement of the fetus sensed by the mother.
- Fetal quickening typically occurs at 18-20 weeks in a first-time pregnancy, and 16-18 weeks in subsequent pregnancies.
Normal Vaginal Delivery
- NVD (Normal Vaginal Delivery) refers to a vaginal delivery that is single, spontaneous, term, viable in a vertex presentation.
- Episiotomy can be considered part of a NVD.
Pelvic Examinations
-
Indications for pelvic examinations include:
- Excessive or offensive discharge
- Vaginal bleeding
- Cervical smear
- Rupture of membranes (ROM)
-
Contraindications to digital examination include:
- Known case of placenta praevia
- Vaginal bleeding when the placental site is unknown and the presenting part unengaged
- PROM
- Virgin females
Effects of Alcohol & Smoking
- Smoking causes a reduction in birthweight and increases the risk of miscarriage, stillbirth, and neonatal death.
- Alcohol can lead to fetal alcohol syndrome, causing brain damage and growth problems.
Antenatal Care
- Antenatal care typically includes:
- Controlling weight gain in pregnancy
- General exercise advice, focusing on pelvic floor exercises
- Breastfeeding advice, encouraging early breastfeeding, and exclusive breastfeeding for the first 6 months.
- Antenatal urine tests, including checking for protein, glucose, nitrites.
- Blood pressure assessment.
- Anti-D immunoglobulin prophylaxis for Rh-negative women.
- Glucose tolerance tests for women with a history of GDM.
- Screening for thalassaemia using the Family Origin Questionnaire (FOQ)
Benefits of Dating Ultrasound
- Dating ultrasound is used to determine gestational age (GA) and estimated due date (EDD).
- There should not be a difference of more than 2 weeks between the calculated GA and the ultrasound GA.
- Ultrasound is accurate within:
- ± 1 week in the first trimester (11+3 - 13+6 weeks)
- ± 2 weeks in the second trimester (14 - 20 weeks)
- ± 3 weeks in the third trimester (after 20 weeks)
Ultrasound Applications
- Ultrasound can:
- Provide an accurate estimate of GA
- Detect multiple pregnancies and chorionicity
- Detect fetal abnormalities.
Multiple Pregnancies
- The risk of premature delivery increases with each additional fetus.
- Triplets typically deliver around 32 weeks.
- Quadruplets typically deliver around 28 weeks.
Polyhydramnios
- Can be managed with amnio-drainage, but this can lead to premature labor and rupture of membranes.
- Indomethacin can be used to reduce fetal urine production.
- Monitor ductus arteriosus flow as indomethacin may cause premature closure.
Mullerian Anomalies
- Result from abnormal embryonic fusion and canalization of müllerian ducts.
- Can lead to abnormal uterine cavity shapes.
- May increase the risk of miscarriage, premature rupture of membranes, preterm labor, intrauterine growth restriction, breech presentation, and cesarean section.
Placenta Abruption
- Placenta abruption can cause bleeding, which releases thrombin and stimulates myometrial contractions leading to premature labor.
Preterm Labor (PTL)
-
Management of threatened preterm labor includes:
- Testing for cervicovaginal fetal fibronectin (fFN):
- Negative: discharge home.
- Positive: admission and start treatments
-
Treatments:
- Progesterone
- Corticosteroids
- Tocolytics
- Antibiotics (erythromycin)
- Testing for cervicovaginal fetal fibronectin (fFN):
Tocolytic Agents
-
Tocolytic agents delay delivery and include:
- OTR-A (Atosiban)
- MgSO4
- CCB (Nifedipine)
- NSAID (Indomethacin)
- β2 agonists (Ritodrine, Salbutamol, Terbutaline)
Side Effects of Tocolytic Agents
- Atosiban has the fewest side effects and best neonatal outcomes.
- β2 agonists have the most side effects and worst neonatal outcomes.
- CCB have intermediate side effects and neonatal outcomes.
Fetal Death
- Fetal death can be confirmed by:
- Decreased fetal movement
- Lack of pregnancy progression
- Absent fetal heart rate
- US confirmation
- Physical signs of fetal death (skin edema, hydrops, Spalding sign)
Fetal Death Investigation
- Investigations include:
- Excluding pulmonary embolism, abruption, DIC
- CBC, BG/Rh, Kleihauer & Coombs test
- ANA, APA screen
- ToRCH screen
- RBS, A1C, Bile salt
- Baby examination
- Postmortem exam
Treatment of Stillbirth
- Up to 90% of stillbirths deliver spontaneously within 2 weeks.
- Vaginal delivery with adequate analgesia is the preferred option.
- Cesarean section is appropriate in high risk scenarios.
Intrauterine Growth Restriction (IUGR)
-
Diagnosis:
- Determine GA early
- Monitor SFH
- Ultrasound to evaluate fetal growth and amniotic fluid volume
- Biophysical profile (BPP)
- Doppler umbilical blood flow
Complications of IUGR
- IUGR can lead to:
- Fetal and neonatal death
- Prematurity
- Fetal compromise in labor
- Neonatal morbidity
- Induce labor
- Cesarean section
Neonatal Complications of IUGR
- IUGR can result in:
- Meconium aspiration
- Asphyxia
- Polycythemia
- Hypoglycemia
- Mental retardation
- Increased risk of perinatal morbidity and mortality
IUGR and Long-Term Health
- Infants with IUGR are at increased risk of:
- Impaired neurodevelopment
- Type 2 diabetes
- Hypertension in adulthood.
Lupus Nephritis
- Women with SLE are at high risk of lupus nephritis, particularly women with antiphospholipid antibodies and proliferative lupus nephritis.
- Immunosuppressive therapy is used to manage lupus flares.
Renal Transplant and Pregnancy
- Women with a renal transplant are at increased risk of:
- Low birth weight
- Preterm delivery
- Ectopic pregnancy
Thyroid in Pregnancy
-
Physiological changes include:
- Increased hCG leading to increased fT4 and decreased TSH.
- Increased E2 leading to increased TBG.
- Thyroid hormone is transferred to the fetus.
Hypothyroidism
- Most common cause: Hashimoto's thyroiditis.
-
Complications:
- Pregnancy loss
- Abruption
- Gestational hypertension/preeclampsia
- Preterm labor
- Developmental delay
Hepatitis B in Pregnancy
-
Management:
- Passive immunoglobulin for newborns of mothers with high infectivity.
- Active hepatitis B vaccine for newborns of mothers with low infectivity.
Pregnancy Dates
- Normal delivery occurs between 37 and 42 weeks
- Pregnancy is considered full-term at 40 weeks, which is calculated from the last menstrual period (LMP)
- Pregnancy from the point of conception is 38 weeks
Gravidity and Parity
- Gravidity refers to the number of pregnancies a woman has had, regardless of outcome
- Parity refers to the number of deliveries after 24 weeks gestation, regardless of whether the baby was born alive or dead
- Abortion refers to pregnancies that ended before 24 weeks, including ectopic and molar pregnancies
- A nulligravida is a woman who has never been pregnant
- A primigravida is a woman pregnant for the first time
- A multigravida is a woman pregnant more than once
- A nullipara is a woman who has never carried a pregnancy beyond 24 weeks
- A primipara is a woman who has given birth once before
- A multiparous woman has given birth more than once
- A grand multipara is a woman who has given birth 3 or more times
Fetal Quickening
- Fetal quickening is the first fetal movement felt by the mother
- It occurs around 18-20 weeks in primigravidas and 16-18 weeks in multiparas
Normal Vaginal Delivery (NVD)
- NVD refers to a single, spontaneous, term, viable, and vertex delivery without the use of instruments
- Episiotomy is considered normal vaginal delivery but perineal tears are not
Pelvic Examinations
- Indications for pelvic examinations include excessive or offensive discharge, vaginal bleeding in the absence of placenta praevia, cervical smear, and rupture of membranes
- Contraindications to digital examination include known placenta praevia, vaginal bleeding when the placental site is unknown and the presenting part unengaged, pre-mature rupture of membranes, and virgin females
Alcohol and Smoking Effects on the Fetus
- Smoking during pregnancy can reduce birth weight, increase the risk of miscarriage, stillbirth and neonatal death
- Alcohol consumption during pregnancy can cause fetal alcohol syndrome, leading to brain damage and growth problems
Antenatal Care
- Antenatal care is the medical care provided to pregnant women during pregnancy
- It includes regular checkups, monitoring weight gain, and screening for potential complications
- The goals of exercise during pregnancy include staying fit and reducing the risk of urinary and fecal incontinence
- Breastfeeding offers protection against diarrhea, common childhood illnesses like pneumonia, and reduces the risk of obesity later in life
- Breastfeeding is associated with higher intelligence quotient (IQ) in children
- Start breastfeeding within an hour of birth, exclusively breastfeed for the first 6 months and continue breastfeeding for at least 2 years
- Antenatal urine tests screen for protein, persistent glycosuria, nitrites
- Blood pressure assessment during antenatal care allows detection of chronic hypertension
- Antenatal anti-D immunoglobulin prophylaxis is given at 28 and 34 weeks to prevent Rh incompatibility
- Women with previous gestational diabetes should be offered a glucose tolerance test in the first trimester
- Screening for thalassaemia is offered to all pregnant women at the booking visit
Dating Ultrasound (US)
- Dating US is used to determine gestational age and estimated date of delivery (EDD)
- US is used to measure crown-rump length (CRL) between 11+3 and 13+6 weeks, head circumference (HC) between 14 and 20 weeks, and femoral length (FL) after 20 weeks
- The accuracy of gestational age determined by US is ± 1 week in T1, ± 2 week in T2, and ± 3 week in T3
- Benefits of dating US: accurate dating for women with irregular cycles, decreased incidence of induction of labor for prolonged pregnancies, maximized potential for serum screening, detection of multiple pregnancies
Maternal Mortality
- Most maternal deaths occur within the first week after delivery
- Death rates rise with parity and maternal age
- PPH, eclampsia, and sepsis are leading causes of maternal deaths
Perinatal and Neonatal Mortality
- Fetal causes of perinatal and neonatal mortality include placental insufficiency, intrauterine infection, severe congenital malformations, umbilical cord accident, abruptio placentae, and hydrops fetalis
- Preterm causes of perinatal and neonatal mortality include severe immaturity, respiratory distress syndrome, intraventricular hemorrhage, congenital anomalies, infection, necrotizing enterocolitis, and bronchopulmonary dysplasia (BPD)
- Full term causes of perinatal and neonatal mortality include congenital anomalies, birth asphyxia, trauma, infection, meconium aspiration pneumonia, and persistent pulmonary hypertension (PPHN)
Antepartum Haemorrhage (APH)
- APH refers to bleeding from the genital tract after 24 completed weeks of gestation and before the onset of labor
- Causes of APH include placenta praevia, abruption placentae, local causes (cervical erosion, polyp, ectropion, cancer, genital tract infection, vaginal varicosities), blood dyscrasias, and undetermined causes
- Vasa praevia is a rare fetal cause of APH
- Placenta praevia occurs when the placenta is implanted wholly or partially on the lower segment of the uterus
- Placenta praevia risk factors include multiparity, multiple pregnancy, increasing maternal age, C-section or uterine surgery, D&C, IVF, and smoking
- There are four grades of placenta praevia based on the location of the placenta in relation to the internal os
- Grades I and II are considered minor, while Grades III and IV are considered major
- Associated conditions with placenta praevia include abnormal fetal lie, malpresentation, pre-mature rupture of membranes, intrauterine growth restriction (IUGR), operative delivery, and morbidly adherent placenta (accreta)
- Migration of the placenta may occur as the lower uterine segment develops
- Types of spontaneous abortion include threatened, inevitable, missed, incomplete, complete, and septic
Anemia
- Normal Hb levels during pregnancy are >11 in T1, >10.5 in T2 and T3, >10 postpartum, and >11 after puerperium
- The most common causes of anemia during pregnancy and the puerperium are iron deficiency and acute blood loss
- Causes of anemia are categorized according to MCV (mean corpuscular volume)
- Microcytic anemia is characterized by small red blood cells and is commonly caused by iron deficiency
- Megaloblastic anemias, liver disease, alcohol consumption, hemoglobinopathies, metabolic disorders, marrow disorders, and increased destruction can also lead to anemia
- Anemia during pregnancy can have various effects on both the mother and the baby
- Maternal effects include pre-eclampsia, preterm labor, heart failure, PPH, shock, cardiac arrest, puerperal sepsis, poor lactation, thromboembolism, and poor wound healing
- Fetal effects of anemia include low birth weight, intrauterine growth restriction, and anemia in infancy
- Symptoms of iron deficiency anemia include difficulty concentrating, pica, glossitis, cheilosis, koilonychia, and dysphagia
- CBC (complete blood count) should be performed at the booking visit (9-12 weeks), 28 weeks, 32 weeks, and in cases of multiple pregnancy
- Anemia during pregnancy can be managed with iron supplements (oral and parenteral) and blood transfusions
- Blood transfusion is indicated if Hb is <7
- Diabetic nephropathy may develop worsening proteinuria and hypertension
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Test your knowledge on key topics related to obstetrics and pregnancy, including exercise, ultrasound accuracy, and breastfeeding practices. This quiz covers essential aspects of prenatal care and delivery that every expecting parent should be aware of.