Obstetric History: Key Terms and Gestational Age

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Questions and Answers

A 35-year-old patient with a history of two prior pregnancies presents for her third prenatal visit. Her obstetric history includes a term delivery of twins at 38 weeks and a spontaneous abortion at 10 weeks. How would you correctly document her obstetric history using both the Gravida/Para notation and TPAL notation respectively?

  • G2P1 / T1P0A1L2
  • G3P1 / T1P0A1L0
  • G3P2 / T1P1A1L2
  • G3P1 / T1P0A1L2 (correct)

A patient's last menstrual period (LMP) was on October 20, 2024. Based on Naegele's Rule, what is the estimated date of delivery (EDD), and what key assumption underlies the accuracy of this calculation?

  • August 1, 2025, not accounting for variations in cycle length or ovulation timing.
  • July 20, 2025, assuming a regular 30-day menstrual cycle and fertilization occurring at the midpoint.
  • July 27, 2025, assuming a regular 28-day menstrual cycle and fertilization occurring 14 days after the start of the LMP. (correct)
  • July 13, 2025, assuming a 28-day cycle and ovulation occurring precisely on day 14.

A patient presents with a positive urine pregnancy test. Serial serum β-hCG measurements are taken 48 hours apart. The initial β-hCG level is 150 mIU/mL, and the subsequent level is 210 mIU/mL. Considering the expected rate of increase in early pregnancy, what is the MOST appropriate next step in managing this patient?

  • Reassure the patient that the pregnancy is progressing normally, as the β-hCG levels fall within the expected range of doubling every 48 hours.
  • Order a repeat β-hCG level in another 48 hours to assess the trend more accurately before considering further intervention. (correct)
  • Prescribe progesterone supplementation, as the sub-optimal rise in β-hCG suggests possible luteal phase deficiency.
  • Immediately order a transvaginal ultrasound to evaluate for ectopic pregnancy due to the sub-optimal rise in β-hCG.

In the evaluation of early pregnancy via transvaginal ultrasound, what is the MOST critical factor to consider when using gestational sac diameter alone to estimate gestational age, especially in light of potential variations in individual embryonic development and implantation timing?

<p>The variability in gestational sac growth rates necessitates correlation with other sonographic markers like the yolk sac and fetal pole for accurate dating. (C)</p> Signup and view all the answers

During a first-trimester ultrasound at 8 weeks gestation by LMP, the crown-rump length (CRL) measurement estimates the gestational age at 7 weeks and 2 days. The patient is certain of her LMP date. How should this discrepancy be managed, considering the accuracy of CRL measurements and potential implications for future prenatal care?

<p>The EDD should be revised based on the CRL measurement, and subsequent prenatal care should be guided by the ultrasound dating. (A)</p> Signup and view all the answers

A patient presents for an initial prenatal visit, reporting a history of irregular menstrual cycles, making the last menstrual period unreliable for dating the pregnancy. An early ultrasound reveals a gestational sac, but no visible yolk sac or fetal pole. The quantitative β-hCG level is 2,500 mIU/mL. What is the MOST appropriate next step in evaluating this pregnancy?

<p>Repeat the ultrasound in 3-5 days, as the yolk sac should be visible with a β-hCG level above 2,000 mIU/mL, if it is an intrauterine pregnancy. (D)</p> Signup and view all the answers

A patient with a history of recurrent pregnancy loss presents for early pregnancy evaluation. Her initial β-hCG level is within normal limits, but the rate of increase is slower than expected. Recognizing the limitations of β-hCG trends in predicting pregnancy outcomes, what additional diagnostic modality would provide the MOST clinically significant information in this specific scenario?

<p>High-resolution transvaginal ultrasonography with Doppler studies to assess early placental perfusion and embryonic cardiac activity. (C)</p> Signup and view all the answers

A patient presents at 9 weeks gestation by LMP. Transvaginal ultrasound reveals a crown-rump length consistent with 8 weeks and 1 day. Considering the established accuracy ranges for first trimester ultrasound dating, particularly between 9 and 13 weeks gestation, what is the MOST appropriate course of action concerning the estimated due date (EDD)?

<p>The EDD should be revised to align with the ultrasound dating, as the discrepancy exceeds the acceptable range of variation. (C)</p> Signup and view all the answers

Flashcards

Gravida

Number of pregnancies a woman has had, regardless of outcome.

Para

Number of completed pregnancies (greater than 20 weeks).

Nulligravida

Woman who has never been pregnant.

Multigravida

A woman who has been pregnant more than once.

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Term Birth

Delivery at > 37 weeks’ gestation

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Preterm Birth

Delivery at 20 to < 37 weeks’ gestation

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Gestational Age

Weeks since the last menstrual period.

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Naegele’s Rule

Last menstrual period + 7 days – 3 months

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Study Notes

  • Obstetric history involves tracking a woman's pregnancies and births.

Key Terms

  • Gravida refers to the number of pregnancies a woman has had.
  • Nulligravida describes a woman who has never been pregnant.
  • Multigravida indicates a woman who has been pregnant more than once.
  • Para is the number of completed pregnancies exceeding 20 weeks.
  • G1P0 signifies a first pregnancy with no prior births.
  • Multiple gestations count as a single birth for parity.
  • TPAL is an expanded obstetric history that includes term births, preterm births, abortions, and living children.
  • T represents term births (deliveries at >37 weeks' gestation).
  • P represents preterm births (deliveries at 20 to <37 weeks' gestation).
  • A represents abortions.
  • L represents living children.

Gestational Age

  • Gestational age is the weeks since the last menstrual period and conception occurs about 2 weeks (15 days) before the missed period.
  • Term is 37 weeks or more.
  • Preterm is less than 37 weeks.
  • Postterm is greater than 42 weeks.

Naegele's Rule

  • EDD (estimated due date) = last menstrual period + 7 days – 3 months

Trimesters

  • First trimester: weeks 1 to 12
  • Second trimester: weeks 13 to 27
  • Third trimester: weeks 28 to birth

Pregnancy Diagnosis

  • Diagnosis relies on detecting human chorionic gonadotropin (hCG).
  • Antibody-based tests target the β subunit of hCG to detect pregnancy.

Serum Tests

  • Serum tests are the most sensitive for detecting hCG, capable of detecting levels as low as 1-2 mIU/mL.
  • Serum tests can be positive within a week post-conception.

Urine Tests

  • Urine tests have an hCG threshold of 20 to 50 mIU/mL and may not be positive until 2 or more weeks post-conception.

Beta-hCG

  • Beta-hCG levels double approximately every 48 hours initially and need to increase by a minimum of 60% over 48 hours.
  • Beta-hCG peaks around 100,000 mIU/mL by 8 to 10 weeks, declining to about 12,000 mIU/mL at 20 weeks.
  • Beta-hCG cannot determine gestational age due to the wide range of peak and level values.
  • Beta-hCG is typically measured twice at the onset of pregnancy for diagnostic purposes.
  • Beta-hCG is not routinely measured later in pregnancy.

Ultrasound

  • Ultrasound confirms intrauterine pregnancy after positive β-hCG testing and is the most accurate method for pregnancy dating in the 1st trimester.
  • Gestational sac can be seen at 4.5 to 5 weeks.
  • Yolk sac can be seen at 5 to 6 weeks.
  • Fetal pole can be seen at 5.5 to 6 weeks.

Pregnancy Dating

  • Crown-rump length is used in the first trimester (less than 13 weeks) and is the most accurate biometric parameter for pregnancy dating.
  • Pregnancy dating is accurate to ± 5 days if done before ≤ 9 weeks of gestation.
  • Pregnancy dating is accurate to ± 7 days from 9 to 13 weeks.

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