Obesity Treatment Medications Overview

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Which of the following is NOT a type of anti-obesity drug currently in development?

Cholesterol-lowering agents (correct)

Gut hormones and incretin targets

Anti-obesity vaccines

Centrally acting agents

Which of the following is a dual action GLP-1/glucagon receptor agonist?

Tesofensine

Oxyntomodulin (correct)

Velneperit

Setmelanotide

What type of receptor is targeted by cannabinoid type-1 receptor blockers?

Neuropeptide Y receptor

Fibroblast growth factor 21 receptor

Glucagon-like peptide-1 receptor

Cannabinoid type-1 receptor (correct)

Which of the following is a triple agonist?

Tri-agonist 1706 Signup and view all the answers

What is the mechanism of action of the methionine aminopeptidase 2 inhibitor beloranib?

Inhibiting methionine aminopeptidase 2 Signup and view all the answers

Which of the following is a potential adverse effect of using lorcaserin with drugs that affect serotonin?

Increased potential for serotonin syndrome Signup and view all the answers

What is the main purpose of anorexiants in the treatment of obesity?

To stimulate satiety centers in the brain Signup and view all the answers

Which of the following anorexiants was voluntarily withdrawn from the U.S. market due to cardiovascular side effects in October 2010?

Sibutramine Signup and view all the answers

Why were fenfluramine (Pondimin) and dexfenfluramine (Redux) removed from the market in 1997?

They caused fatal cardiac and pulmonary adverse reactions Signup and view all the answers

What is the pharmacodynamic mechanism of anorexiants in the treatment of obesity?

By stimulating satiety centers in the brain Signup and view all the answers

Which of the following anorexiants is chemically and pharmacologically related to amphetamines?

Benzphetamine Signup and view all the answers

Which two drugs are available for chronic weight management as unique combinations?

Phentermine and topiramate Signup and view all the answers

What is the primary mechanism of action of lorcaserin in promoting satiety?

Activation of 5-HT2C receptors in the hypothalamus Signup and view all the answers

Which of the following statements about the pharmacokinetics of anorexiants is correct?

Anorexiants are absorbed in the stomach and small intestine and have a longer duration of action in the extended-release form Signup and view all the answers

Which of the following is a known contraindication for the use of anorexiants?

All of the above Signup and view all the answers

What is the mechanism of action of topiramate in combination with phentermine for weight loss?

The exact mechanism is unknown, but topiramate is known to cause appetite suppression and satiety Signup and view all the answers

Which of the following is a potential adverse effect of lorcaserin?

Hypoglycemia in patients with type 2 diabetes mellitus on antidiabetic therapy Signup and view all the answers

What is the primary route of administration for liraglutide?

Subcutaneous Signup and view all the answers

Which of the following is a contraindication for the use of liraglutide?

Both a and b Signup and view all the answers

What is the typical half-life of anorexiants?

8-20 hours Signup and view all the answers

Which of the following adverse reactions is commonly associated with the use of liraglutide?

Nausea, vomiting, and diarrhea Signup and view all the answers

What is the main concern with long-term use of anorexiants?

Potential for tolerance and dependence Signup and view all the answers

Which of the following is NOT a potential adverse effect associated with liraglutide?

Hypoglycemia Signup and view all the answers

What is the recommended course of treatment duration for anorexiants?

No longer than 6 months Signup and view all the answers

Which of the following statements regarding lorcaserin is TRUE?

It should be used with caution with serotonergic agents Signup and view all the answers

Which of the following anorexiants is considered one of the safest for patients with mild to moderate hypertension or angina pectoris?

Diethylpropion Signup and view all the answers

What is the recommended starting dose of liraglutide in the first week?

0.6 mg Signup and view all the answers

Which of the following statements regarding anorexiants and evening dosing is TRUE?

Evening dosing should generally be avoided due to the likelihood of insomnia Signup and view all the answers

Which of the following is a potential drug interaction associated with anorexiants?

All of the above Signup and view all the answers

Which of the following statements regarding liraglutide administration is TRUE?

It can be taken at any time of day, without regard to mealtimes Signup and view all the answers

Which of the following is a potential adverse effect associated with liraglutide?

All of the above Signup and view all the answers

Which of the following anorexiants is NOT a stimulant?

Lorcaserin Signup and view all the answers

Obesity Treatment Medications Overview

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Questions and Answers

Which of the following is NOT a type of anti-obesity drug currently in development?

Which of the following is a dual action GLP-1/glucagon receptor agonist?

What type of receptor is targeted by cannabinoid type-1 receptor blockers?

Which of the following is a triple agonist?

What is the mechanism of action of the methionine aminopeptidase 2 inhibitor beloranib?

Which of the following is a potential adverse effect of using lorcaserin with drugs that affect serotonin?

What is the main purpose of anorexiants in the treatment of obesity?

Which of the following anorexiants was voluntarily withdrawn from the U.S. market due to cardiovascular side effects in October 2010?

Why were fenfluramine (Pondimin) and dexfenfluramine (Redux) removed from the market in 1997?

What is the pharmacodynamic mechanism of anorexiants in the treatment of obesity?

Which of the following anorexiants is chemically and pharmacologically related to amphetamines?

Which two drugs are available for chronic weight management as unique combinations?

What is the primary mechanism of action of lorcaserin in promoting satiety?

Which of the following statements about the pharmacokinetics of anorexiants is correct?

Which of the following is a known contraindication for the use of anorexiants?

What is the mechanism of action of topiramate in combination with phentermine for weight loss?

Which of the following is a potential adverse effect of lorcaserin?

What is the primary route of administration for liraglutide?

Which of the following is a contraindication for the use of liraglutide?

What is the typical half-life of anorexiants?

Which of the following adverse reactions is commonly associated with the use of liraglutide?

What is the main concern with long-term use of anorexiants?

Which of the following is NOT a potential adverse effect associated with liraglutide?

What is the recommended course of treatment duration for anorexiants?

Which of the following statements regarding lorcaserin is TRUE?

Which of the following anorexiants is considered one of the safest for patients with mild to moderate hypertension or angina pectoris?

What is the recommended starting dose of liraglutide in the first week?

Which of the following statements regarding anorexiants and evening dosing is TRUE?

Which of the following is a potential drug interaction associated with anorexiants?

Which of the following statements regarding liraglutide administration is TRUE?

Which of the following is a potential adverse effect associated with liraglutide?

Which of the following anorexiants is NOT a stimulant?

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