Podcast
Questions and Answers
What is the critical brain area for energy balance and leptin sensitivity?
What is the critical brain area for energy balance and leptin sensitivity?
- Cerebellum
- Arcuate Nucleus (correct)
- Medulla Oblongata
- Hippocampus
Which type of neurons in the arcuate nucleus decrease appetite?
Which type of neurons in the arcuate nucleus decrease appetite?
- Glutamatergic neurons
- NPY/AgRP neurons
- GABAergic neurons
- POMC neurons (correct)
What hormone opposes leptin's inhibitory action by activating NPY/AgRP neurons?
What hormone opposes leptin's inhibitory action by activating NPY/AgRP neurons?
- Insulin
- Cortisol
- Ghrelin (correct)
- Adrenaline
What is frequently used as a marker to assess the effectiveness of leptin signaling?
What is frequently used as a marker to assess the effectiveness of leptin signaling?
Which type of neurons in the arcuate nucleus increase appetite?
Which type of neurons in the arcuate nucleus increase appetite?
What was used to visualize neuronal activity in real-time during feeding behavior experiments?
What was used to visualize neuronal activity in real-time during feeding behavior experiments?
What is the therapeutic potential of leptin in combating obesity?
What is the therapeutic potential of leptin in combating obesity?
Why was the efficacy of leptin as an anti-obesity drug questioned in subsequent studies?
Why was the efficacy of leptin as an anti-obesity drug questioned in subsequent studies?
What is the primary feature of leptin resistance?
What is the primary feature of leptin resistance?
How is leptin resistance believed to develop?
How is leptin resistance believed to develop?
What initiates the leptin signaling cascade in the body?
What initiates the leptin signaling cascade in the body?
What aspect of leptin remains a complex challenge in neuroendocrinology despite research efforts?
What aspect of leptin remains a complex challenge in neuroendocrinology despite research efforts?
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