Malabsorption and diarrhea Quiz L4,5
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Questions and Answers

Which phase of nutrient absorption involves the hydrolysis of complex molecules?

  • Intraluminal digestion
  • Transepithelial transport
  • Lymphatic transport
  • Terminal digestion (correct)
  • Which condition is caused by a tumor that secretes excessive gastrin?

  • Zollinger-Ellison syndrome (correct)
  • Obstructive jaundice
  • Cystic fibrosis
  • Postgastrectomy
  • What is the characteristic stool appearance in steatorrhea?

  • Dark and tarry stools
  • Loose and watery stools
  • Pale, foul-smelling, greasy stools that float in water (correct)
  • Bloody stools
  • Which genetic disorder leads to low or absent levels of plasma cholesterol, LDLs, and VLDLs?

    <p>Abetalipoproteinemia</p> Signup and view all the answers

    Which condition can cause growth retardation and failure to thrive in children?

    <p>Cystic fibrosis</p> Signup and view all the answers

    What is a common systemic effect of malabsorption?

    <p>Deficiency of fat-soluble vitamins (A, K, E, D), minerals, protein, and carbohydrate</p> Signup and view all the answers

    What is the main purpose of the gastrointestinal tract?

    <p>To digest and absorb nutrients, water, minerals, and electrolytes</p> Signup and view all the answers

    Which organ systems can be affected by malabsorption?

    <p>Alimentary tract, hematopoietic system, musculoskeletal system</p> Signup and view all the answers

    What are the major causes of acute diarrhea?

    <p>Infections, medications, dietary indiscretion</p> Signup and view all the answers

    What aspects of celiac disease should be known?

    <p>Definition, pathogenesis, clinical features</p> Signup and view all the answers

    What causes malabsorption in the small intestine?

    <p>Abnormal digestion or small intestinal mucosal disease</p> Signup and view all the answers

    What is the cause of Lactose intolerance?

    <p>Lack of lactase enzyme</p> Signup and view all the answers

    What is a potential complication of a 150 cm small bowel resection?

    <p>Steatorrhea</p> Signup and view all the answers

    Which immune diseases are associated with celiac disease?

    <p>Type 1 diabetes, thyroiditis, Sjögren syndrome</p> Signup and view all the answers

    What is the cause of lactose intolerance?

    <p>Deficiency or absence of the enzyme lactase</p> Signup and view all the answers

    How is malabsorption syndrome diagnosed?

    <p>Stool studies, blood tests, endoscopy</p> Signup and view all the answers

    What is a potential complication of celiac disease?

    <p>Osteopenia, osteoporosis, infertility</p> Signup and view all the answers

    What is the major histopathological appearance in celiac disease patients?

    <p>Villous hypertrophy</p> Signup and view all the answers

    What is the most common cause of malabsorption due to inadequate digestion?

    <p>Celiac disease</p> Signup and view all the answers

    What can be used to diagnose various causes of diarrhea?

    <p>Stool analysis including fecal leukocytes, fat test, and serology tests</p> Signup and view all the answers

    What does the presence of E. coli on gram stain in a patient with high volume diarrhea and negative fecal leukocytes suggest?

    <p>Bacterial cause of diarrhea, classified as infectious diarrhea</p> Signup and view all the answers

    What is the major complication of chronic diarrhea?

    <p>Fluid and electrolyte loss</p> Signup and view all the answers

    What is a common cause of acute antibiotic-associated diarrhea?

    <p>Clostridium difficile infection</p> Signup and view all the answers

    What is the main cause of osmotic diarrhea?

    <p>Ingestion of poorly absorbable solutes such as lactulose or disaccharides</p> Signup and view all the answers

    What distinguishes secretory diarrhea from osmotic diarrhea?

    <p>Loss of isotonic fluid and an increase in active secretion of water</p> Signup and view all the answers

    What is the primary cause of exudative diarrhea?

    <p>Invasive infections or inflammatory bowel diseases</p> Signup and view all the answers

    How can the causes of diarrhea be distinguished based on the stool osmotic gap?

    <p>Normal or low stool osmotic gap for malabsorption and high for secretory or osmotic diarrhea</p> Signup and view all the answers

    Which test can be used as a screening test for diarrhea to suggest inflammation in the bowel?

    <p>Fecal smear for leukocytes</p> Signup and view all the answers

    What are the main causes of child deaths mentioned in the text?

    <p>Diarrhea, pneumonia, malaria, preterm delivery, neonatal infection</p> Signup and view all the answers

    What is the characteristic stool appearance in steatorrhea?

    <p>Loose, foul-smelling, and greasy</p> Signup and view all the answers

    Which immune diseases are associated with celiac disease?

    <p>Type 1 diabetes, thyroiditis, Sjögren syndrome</p> Signup and view all the answers

    What is the major complication of chronic diarrhea?

    <p>Malnutrition and dehydration</p> Signup and view all the answers

    What distinguishes secretory diarrhea from osmotic diarrhea?

    <p>Continues despite fasting</p> Signup and view all the answers

    What is the cause of Lactose intolerance?

    <p>Deficiency or absence of the enzyme lactase</p> Signup and view all the answers

    What can be used to diagnose various causes of diarrhea?

    <p>Stool studies, blood tests, endoscopy</p> Signup and view all the answers

    What are the major causes of acute diarrhea?

    <p>Viral, bacterial, and parasitic infections</p> Signup and view all the answers

    What distinguishes secretory diarrhea from osmotic diarrhea?

    <p>Secretory diarrhea continues even with fasting, while osmotic diarrhea stops with fasting</p> Signup and view all the answers

    What distinguishes celiac disease from other causes of malabsorption?

    <p>Presence of characteristic histopathological features in the small intestine</p> Signup and view all the answers

    Which immune diseases are associated with celiac disease?

    <p>Type 1 diabetes mellitus and autoimmune thyroid disease</p> Signup and view all the answers

    What can be used to diagnose various causes of diarrhea?

    <p>Stool analysis for leukocytes, fecal lactoferrin, and stool culture</p> Signup and view all the answers

    What causes malabsorption in the small intestine?

    <p>Abnormal digestion or small intestinal mucosal disease</p> Signup and view all the answers

    Which condition is not a common cause of malabsorption due to inadequate digestion?

    <p>Chronic pancreatitis</p> Signup and view all the answers

    What is the major histopathological appearance in patients with celiac disease?

    <p>Villous hypertrophy</p> Signup and view all the answers

    What is the most common cause of chronic diarrhea in patients with high volume diarrhea and negative fecal leukocytes?

    <p>Bacterial infection</p> Signup and view all the answers

    Which immune diseases are associated with celiac disease?

    <p>Type 1 diabetes mellitus</p> Signup and view all the answers

    What is the primary cause of exudative diarrhea?

    <p>Inflammatory bowel disease</p> Signup and view all the answers

    What is a potential complication of chronic diarrhea?

    <p>Hypokalemia and metabolic alkalosis</p> Signup and view all the answers

    Which condition is caused by a rare autosomal recessive disorder characterized by low or absent levels of plasma cholesterol, LDLs, and VLDLs?

    <p>Abetalipoproteinemia</p> Signup and view all the answers

    What can cause malabsorption due to deficiency of pancreatic lipase?

    <p>Postgastrectomy</p> Signup and view all the answers

    Which disorder is characterized by mutations in the CFTR gene leading to dysfunction of chloride channels and resulting in hyperviscous mucus and secretion accumulation?

    <p>Cystic fibrosis</p> Signup and view all the answers

    What can lead to bacterial overgrowth, causing inflammation and flattened intestinal villi?

    <p>Hypomotility states</p> Signup and view all the answers

    "Steatorrhea" is a symptom of malabsorption characterized by what type of stool appearance?

    <p>&quot;Pale, foul-smelling, greasy stools that float in water&quot;</p> Signup and view all the answers

    "Tropical sprue" is caused by bacterial overgrowth and primary mucosal abnormalities resulting from the release of toxins by which bacteria?

    <p>&quot;Klebsiella and E. coli&quot;</p> Signup and view all the answers

    What is the primary cause of osmotic diarrhea?

    <p>Ingestion of poorly absorbable solutes such as lactulose or disaccharides</p> Signup and view all the answers

    What distinguishes secretory diarrhea from osmotic diarrhea?

    <p>Lack of response to fasting</p> Signup and view all the answers

    Which test can be used as a screening test for diarrhea to suggest inflammation in the bowel?

    <p>Fecal smear for leukocytes</p> Signup and view all the answers

    What is the most common cause of bacterial dysentery?

    <p>Shigella</p> Signup and view all the answers

    What is a potential complication of celiac disease?

    <p>Malabsorption of nutrients</p> Signup and view all the answers

    What are the main causes of child deaths mentioned in the text?

    <p>Diarrheal diseases</p> Signup and view all the answers

    Study Notes

    • Unabsorbed lactose in the intestine attracts water due to its presence.

    • In the colon, lactose is metabolized by bacteria into organic acids, CO2, and H2, causing irritation and osmotic effect leading to diarrhea, gaseousness, bloating, and abdominal cramps.

    • Approximately 8500 mL of fluid flows into the intestine daily, from diet (1500mL) and secretions (7000mL), with around 7000 mL absorbed in the small intestines.

    • Approximately 1500 mL passes through the ileocecal valve, and around 1400 cc of fluid is absorbed in the large bowel, with only 100 cc excreted.

    • Diarrhea is a common cause of child deaths, and dehydration and electrolyte imbalances are possible consequences of it.

    • Fecal osmolarity is equal to serum osmolarity (290 mosm/kg) with the major osmoles being Na+, K+, Cl–, and HCO –3.

    • Fecal osmotic gap, calculated to distinguish different causes of diarrhea, is normal (<100 mOsm/kg) or increased (>125 mOsm/kg), with the latter implying osmotic diarrhea caused by unabsorbed molecules such as unabsorbed carbohydrates.

    • Secretory diarrhea is characterized by the loss of isotonic fluid and an increase in active secretion of water, and is caused by enterotoxins that stimulate chloride channels regulated by cAMP and cGMP.

    • Osmotic diarrhea is characterized by a lack of response to fasting, and is caused by the ingestion of poorly absorbable solutes such as lactulose or disaccharides.

    • Exudative diarrhea results from the outpouring of blood or mucus from an inflamed or ulcerated mucosa and is caused by invasive infections or inflammatory bowel diseases.

    • Bacterial dysentery is a common cause of exudative diarrhea, and the main organisms responsible for it are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear for leukocytes can be used as a screening test for diarrhea, and a positive result suggests inflammation in the bowel.

    • The main causes of diarrhea include bacterial toxins, neuroendocrine tumors, enteropathogenic viruses, laxatives, and malabsorption disorders.

    • The causes of diarrhea can be distinguished based on the stool osmotic gap, which is normal or low in the case of malabsorption and high in the case of secretory or osmotic diarrhea.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Diarrhea can lead to dehydration and electrolyte imbalances, which can be life-threatening, especially in children.

    • The loss of fluids from diarrhea can amount to 200-300 gm/day, almost double the normal amount.

    • The most common causes of child deaths are diarrhea, pneumonia, malaria, preterm delivery, and neonatal infection.

    • Diarrhea can be caused by a bacterial toxin or a neuroendocrine tumor, or by enteropathogenic viruses or rectal villous adenomas.

    • Lactulose and other osmotic laxatives are used to treat diarrhea by increasing the stool's water content.

    • Fecal smear tests for leukocytes and O&P (Ova and parasites) can help diagnose diarrhea caused by infections.

    • Diarrhea caused by inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, can be persistent and can lead to the loss of large volumes of fluid.

    • Diarrhea caused by bacterial dysentery can be life-threatening, especially in young children.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests can help diagnose diarrhea caused by bacterial dysentery, but they may not be useful in cases of diarrhea caused by other causes, such as malabsorption disorders.

    • Diarrhea can have a significant impact on a person's health and quality of life.

    • Fecal smear tests are used to diagnose bacterial infections in the intestines, and a positive result suggests the presence of pathogens in the stool.

    • Enteropathogenic viruses, such as rotavirus and norwalk virus, are common causes of diarrhea, especially in young children.

    • Diarrhea caused by inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, can be chronic and can lead to significant health problems.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests can help diagnose bacterial infections in the intestines, and a positive result suggests the presence of pathogens in the stool.

    • Diarrhea can be caused by a variety of factors, including bacterial infections, viruses, and malabsorption disorders.

    • Diarrhea caused by bacterial infections or malabsorption disorders can be life-threatening, especially in young children.

    • Fecal smear tests are an important tool for diagnosing bacterial infections in the intestines, and a positive result suggests the presence of pathogens in the stool.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests are a relatively simple and cost-effective way to diagnose bacterial infections in the intestines.

    • Diarrhea caused by bacterial infections or malabsorption disorders can be persistent and can significantly impact a person's quality of life.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests are a valuable tool for diagnosing bacterial infections in the intestines and can help guide treatment decisions.

    • Diarrhea caused by bacterial infections or malabsorption disorders can be a significant cause of morbidity and mortality, especially in young children.

    • Fecal smear tests are an important diagnostic tool for identifying bacterial infections in the intestines, and a positive result can help guide treatment decisions.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests are a useful diagnostic tool for identifying bacterial infections in the intestines, and a positive result can help guide treatment decisions.

    • Diarrhea caused by bacterial infections or malabsorption disorders can have a significant impact on a person's health and quality of life.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests are a valuable tool for diagnosing bacterial infections in the intestines and can help guide treatment decisions.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests are a useful diagnostic tool for identifying bacterial infections in the intestines, and a positive result can help guide treatment decisions.

    • Diarrhea caused by bacterial infections or malabsorption disorders can be a significant cause of morbidity and mortality, especially in young children.

    • Fecal smear tests are an important diagnostic tool for identifying bacterial infections in the intestines and can help guide treatment decisions.

    • The most common causes of bacterial dysentery are Campylobacter

    • Unabsorbed lactose in the intestine attracts water due to its presence.

    • In the colon, lactose is metabolized by bacteria into organic acids, CO2, and H2, causing irritation and osmotic effect leading to diarrhea, gaseousness, bloating, and abdominal cramps.

    • Approximately 8500 mL of fluid flows into the intestine daily, from diet (1500mL) and secretions (7000mL), with around 7000 mL absorbed in the small intestines.

    • Approximately 1500 mL passes through the ileocecal valve, and around 1400 cc of fluid is absorbed in the large bowel, with only 100 cc excreted.

    • Diarrhea is a common cause of child deaths, and dehydration and electrolyte imbalances are possible consequences of it.

    • Fecal osmolarity is equal to serum osmolarity (290 mosm/kg) with the major osmoles being Na+, K+, Cl–, and HCO –3.

    • Fecal osmotic gap, calculated to distinguish different causes of diarrhea, is normal (<100 mOsm/kg) or increased (>125 mOsm/kg), with the latter implying osmotic diarrhea caused by unabsorbed molecules such as unabsorbed carbohydrates.

    • Secretory diarrhea is characterized by the loss of isotonic fluid and an increase in active secretion of water, and is caused by enterotoxins that stimulate chloride channels regulated by cAMP and cGMP.

    • Osmotic diarrhea is characterized by a lack of response to fasting, and is caused by the ingestion of poorly absorbable solutes such as lactulose or disaccharides.

    • Exudative diarrhea results from the outpouring of blood or mucus from an inflamed or ulcerated mucosa and is caused by invasive infections or inflammatory bowel diseases.

    • Bacterial dysentery is a common cause of exudative diarrhea, and the main organisms responsible for it are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear for leukocytes can be used as a screening test for diarrhea, and a positive result suggests inflammation in the bowel.

    • The main causes of diarrhea include bacterial toxins, neuroendocrine tumors, enteropathogenic viruses, laxatives, and malabsorption disorders.

    • The causes of diarrhea can be distinguished based on the stool osmotic gap, which is normal or low in the case of malabsorption and high in the case of secretory or osmotic diarrhea.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Diarrhea can lead to dehydration and electrolyte imbalances, which can be life-threatening, especially in children.

    • The loss of fluids from diarrhea can amount to 200-300 gm/day, almost double the normal amount.

    • The most common causes of child deaths are diarrhea, pneumonia, malaria, preterm delivery, and neonatal infection.

    • Diarrhea can be caused by a bacterial toxin or a neuroendocrine tumor, or by enteropathogenic viruses or rectal villous adenomas.

    • Lactulose and other osmotic laxatives are used to treat diarrhea by increasing the stool's water content.

    • Fecal smear tests for leukocytes and O&P (Ova and parasites) can help diagnose diarrhea caused by infections.

    • Diarrhea caused by inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, can be persistent and can lead to the loss of large volumes of fluid.

    • Diarrhea caused by bacterial dysentery can be life-threatening, especially in young children.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests can help diagnose diarrhea caused by bacterial dysentery, but they may not be useful in cases of diarrhea caused by other causes, such as malabsorption disorders.

    • Diarrhea can have a significant impact on a person's health and quality of life.

    • Fecal smear tests are used to diagnose bacterial infections in the intestines, and a positive result suggests the presence of pathogens in the stool.

    • Enteropathogenic viruses, such as rotavirus and norwalk virus, are common causes of diarrhea, especially in young children.

    • Diarrhea caused by inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, can be chronic and can lead to significant health problems.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests can help diagnose bacterial infections in the intestines, and a positive result suggests the presence of pathogens in the stool.

    • Diarrhea can be caused by a variety of factors, including bacterial infections, viruses, and malabsorption disorders.

    • Diarrhea caused by bacterial infections or malabsorption disorders can be life-threatening, especially in young children.

    • Fecal smear tests are an important tool for diagnosing bacterial infections in the intestines, and a positive result suggests the presence of pathogens in the stool.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests are a relatively simple and cost-effective way to diagnose bacterial infections in the intestines.

    • Diarrhea caused by bacterial infections or malabsorption disorders can be persistent and can significantly impact a person's quality of life.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests are a valuable tool for diagnosing bacterial infections in the intestines and can help guide treatment decisions.

    • Diarrhea caused by bacterial infections or malabsorption disorders can be a significant cause of morbidity and mortality, especially in young children.

    • Fecal smear tests are an important diagnostic tool for identifying bacterial infections in the intestines, and a positive result can help guide treatment decisions.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests are a useful diagnostic tool for identifying bacterial infections in the intestines, and a positive result can help guide treatment decisions.

    • Diarrhea caused by bacterial infections or malabsorption disorders can have a significant impact on a person's health and quality of life.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests are a valuable tool for diagnosing bacterial infections in the intestines and can help guide treatment decisions.

    • The most common causes of bacterial dysentery are Campylobacter, Salmonella, Shigella, and Entamoeba histolytica.

    • Fecal smear tests are a useful diagnostic tool for identifying bacterial infections in the intestines, and a positive result can help guide treatment decisions.

    • Diarrhea caused by bacterial infections or malabsorption disorders can be a significant cause of morbidity and mortality, especially in young children.

    • Fecal smear tests are an important diagnostic tool for identifying bacterial infections in the intestines and can help guide treatment decisions.

    • The most common causes of bacterial dysentery are Campylobacter

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    Test your knowledge of nutrient deficiency symptoms and diagnosis with this quiz. Explore the varying signs of protein, vitamin, and mineral deficiencies, and learn about the diagnostic process for malabsorption syndrome.

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