Nursing Practice: Insomnia and Sedatives
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Questions and Answers

What should the NP monitor for in patients taking non-stiumulant or Z-drugs?

  • Suicidal ideation (correct)
  • Sleep quality
  • Dependence
  • Next-day drowsiness

Which drug class is not considered 1st line treatment for insomnia due to its potential for misuse?

  • Antihistamines
  • Melatonin
  • Z-drugs
  • Benzodiazepines (correct)

All of the following are other risk factors for ADHD EXCEPT?

  • Inconsistent parenting practice
  • Phychosocial stress
  • Adverse childhood environment
  • Multiple siblings (correct)

Why should extended-release (ER) formulas be avoided?

<p>They increase the risk of next-day drowsiness (A)</p> Signup and view all the answers

What should be avoided in older adults when prescribing hypnotics?

<p>All of the above (D)</p> Signup and view all the answers

What is recommended as an alternative to z-drugs in older adults?

<p>Melatonin (A)</p> Signup and view all the answers

Why does Ritalin have a low risk for adverse effects?

<p>Because it blocks DA &amp; NE NTMs (D)</p> Signup and view all the answers

All of the following meds block the reuptake of DA & NE because they are inhibitors EXCEPT?

<p>Vyvanse (C)</p> Signup and view all the answers

All of the following coexisting conditions are common causes of insomnia EXCEPT?

<p>COPD, bronchitis, sleep apnea (A)</p> Signup and view all the answers

What percentage of clients with major depressive disorder have insomnia?

<p>60-90% (A)</p> Signup and view all the answers

What medication is more potent than Ritalin?

<p>Dexmehtylphenidate (Focalin) (A)</p> Signup and view all the answers

What type of medication is Ropinirole (Requip)?

<p>Dopamine receptor agonist (A)</p> Signup and view all the answers

What is primary insomnia associated with?

<p>None of the above (D)</p> Signup and view all the answers

What is the difference between primary insomnia and psychiatric insomnia?

<p>Primary insomnia is not associated with psychiatric conditions (C)</p> Signup and view all the answers

What stimulant should be avoided when an MAOI has been taken in the past 14 days?

<p>Amphetamine (Adzenys) (C)</p> Signup and view all the answers

What stimulant is the most abused and diverted drug?

<p>Dextroamphetamine (Adderall) (B)</p> Signup and view all the answers

What is the primary reason to prescribe Z-drugs for PRN use?

<p>Due to the potential for abuse and dependence (C)</p> Signup and view all the answers

What is the effect of higher doses or extended use sleep meds on next-day drowsiness?

<p>It increases the risk (C)</p> Signup and view all the answers

What are the potential adverse effects of Z-drug medication?

<p>All of the above (D)</p> Signup and view all the answers

What is the proportion of clients older than 65 years who have persistent insomnia?

<p>1/3 (A)</p> Signup and view all the answers

What are common characteristics of insomnia according to the American Psychiatric Association?

<p>all of the above (D)</p> Signup and view all the answers

What stimulant is least abused or diverted and is considered a prodrug?

<p>Lisdexamfetamine (Vyvanse) (C)</p> Signup and view all the answers

What is a common trigger for insomnia?

<p>Acute stress (D)</p> Signup and view all the answers

What is the proportion of adults who experience chronic insomnia?

<p>10% (D)</p> Signup and view all the answers

Which type of firing is associated with reward, feeling of euphoria, and abuse potential?

<p>Phasic firing (B)</p> Signup and view all the answers

What type of stimulants have a higher risk of abuse due to it's effect of rapidly increasing phasic firing of DA &NE?

<p>Immediate-release stimulants (C)</p> Signup and view all the answers

What is the effect of extended-release formulations on NE and DA signals that leads to gradual & sustained increases?

<p>They amplify tonic firing (C)</p> Signup and view all the answers

What is the mechanism by which extended-release formulations reduce abuse potential?

<p>By occupying the NE transporter in the prefrontal cortex that enhances tonic firing (B)</p> Signup and view all the answers

Why does atomoxetine lack abuse potential?

<p>It increases DA levels in the PFC, but not in the nucleus accumbens (C)</p> Signup and view all the answers

What non-stimulant enhances precordial function to improve mental focus?

<p>Clonidine (A)</p> Signup and view all the answers

Bupropion (Wellbutrin) is considered?

<p>DA-NE reuptake inhibitor (B)</p> Signup and view all the answers

What non-stimulant is best for patients with concurrent depression and tobacco abuse?

<p>Bupropion (Wellbutrin) (B)</p> Signup and view all the answers

Which medication is a first-line agent for treating Restless Leg Syndrome (RLS)?

<p>Ropinirole (Requip) (A)</p> Signup and view all the answers

What is the location of the 'on switch' in the brain?

<p>Tuberomammillary nucleus (TMN) (A)</p> Signup and view all the answers

What is the function of Guanfacine?

<p>Alpha 2 agonist NE inhibitor (non-stimulant) (D)</p> Signup and view all the answers

What is the effect of Methylphenidate on neurotransmitters?

<p>Blocks DAT and NET (B)</p> Signup and view all the answers

What is the main difference between ADHD symptoms in children and adults?

<p>Children present with hyperactivity, while adults report internal restlessness &amp; difficulty sitting still (A)</p> Signup and view all the answers

What is the function of Melatonin and melatonin receptor agonists?

<p>They are effective hypnotics for sleep onset (B)</p> Signup and view all the answers

Which brain region is responsible for modulating impulsivity?

<p>Orbitofrontal cortex and dorsal anterior cingulate cortex (D)</p> Signup and view all the answers

What part of the brain is associated with hyperactivity in ADHD?

<p>Prefrontal cortex (C)</p> Signup and view all the answers

What is a characteristic of non-stimulant medications?

<p>They are effective for the long-term treatment of comorbid anxiety, depression, or substance abuse because it has no potential for abuse or diversion (D)</p> Signup and view all the answers

All of the following are reasons why non-stimulant medications be used?

<p>When clients response to stimulants alone (D)</p> Signup and view all the answers

What should be monitored when taking non-stimulant drugs?

<p>All of the above (D)</p> Signup and view all the answers

What is a contraindication for concurrent use of non-stimulants?

<p>All of the above (D)</p> Signup and view all the answers

What may non-stimulant medications exacerbate in clients with a history of the disorder?

<p>Depression (C)</p> Signup and view all the answers

What is a characteristic of non-stimulant medications in terms of effectiveness?

<p>They take longer to achieve desired effects than stimulants (C)</p> Signup and view all the answers

Why is withdrawal from non-stimulant medications tapered?

<p>To prevent rebound hypertension and neurological side effects (D)</p> Signup and view all the answers

What is a significant cause of societal morbidity, lost productivity, and reduced quality of life?

<p>Disruption of healthy sleep (C)</p> Signup and view all the answers

What is the recommended approach when using z-drugs?

<p>Use them for the shortest duration possible (A)</p> Signup and view all the answers

This part of the brain contains the "off" switch

<p>Ventrolateral preoptic nucleus (C)</p> Signup and view all the answers

All of the following are sedating antidepressants EXCEPT?

<p>Trazadone (B)</p> Signup and view all the answers

Z-drugs are considered what schedule controlled substance?

<p>IV (C)</p> Signup and view all the answers

Restless Leg Syndrome (RLS) is idiopathic and associated with which of the following conditions

<p>All of the above (D)</p> Signup and view all the answers

Why should z-drugs be avoided in clients with dementia?

<p>Because they can cause falls &amp; cognitive impairment (A)</p> Signup and view all the answers

What is considered a psychiatric 'vital sign'?

<p>Sleep (A)</p> Signup and view all the answers

All of the following are BZOs EXCEPT?

<p>Clonidine (C)</p> Signup and view all the answers

What is the function of dual orexin receptor antagonists (DORA)?

<p>Regulating arousal, wakefulness, and appetite (A)</p> Signup and view all the answers

What is the effect of Valarian root on other sleep medications?

<p>It increases the effects of other sleep medications (e.g, alcohol, BZOs, &amp; narcotics) (D)</p> Signup and view all the answers

What is the function of Ramelteon?

<p>Prescription melatonin receptor 1 &amp; 2 agonist, produced by the pineal gland in response to darkness to help regulate sleep-wake cycle (A)</p> Signup and view all the answers

Daytime NTMs include all of the following EXCEPT?

<p>GABA &amp; Melatonin (D)</p> Signup and view all the answers

Why should Suvorexant be decreased when combined with CYP 450 inhibitors such as diltiazem, erythromycin, & ketoconazole?

<p>Because it can lead to increased sedation and next-day drowsiness (D)</p> Signup and view all the answers

What is the mechanism of action of Z drugs?

<p>Producing a calming effect by binding to GABA receptors (C)</p> Signup and view all the answers

When prescribing non-stimulants it is important to pay special attention to what parts of the clients history?

<p>All of the above (D)</p> Signup and view all the answers

Beers criteria includes all of the following

<p>Avoid prescribing medication at night to prevent falls (D)</p> Signup and view all the answers

alking excessively, blurting out answers in class, & not waiting thier turn are all examples of which ADHD symptoms?

<p>Impulsivity (D)</p> Signup and view all the answers

What medication is recommended to control irritability and help with sleep if taken at bedtime?

<p>Guanfacine (A)</p> Signup and view all the answers

Not listening & making careless mistakes is an example of what ADHD symptoms?

<p>Selective attention (B)</p> Signup and view all the answers

Inability to find the motivation to complete his homework or pay attention in class is an example of what ADHD symptoms?

<p>sustained attention (C)</p> Signup and view all the answers

What is the recommended 1st step to increasing the dose of methylphenidate from 5 mg q day?

<p>Consider a second dose after lunch if appetite is affected (D)</p> Signup and view all the answers

running & climbing on the chairs & desks, trouble playing quietly, & refusing to stay in seat are examples of what ADHD symptoms?

<p>Hyperactivity (D)</p> Signup and view all the answers

Inhibiting NE NTM in the PFC increases what?

<p>Both (D)</p> Signup and view all the answers

Benadryl can cause anticholinergic effects due to the _________ ________.

<p>muscarinic antagonism (A)</p> Signup and view all the answers

What is the primary reason for treating alcohol abuse before treating ADHD and anxiety disorders?

<p>To address the highest degree of impairment (C)</p> Signup and view all the answers

What is the effect of pulsed stimulation on dopamine and norepinephrine firing?

<p>Pulsatile stimulation amplifies undesirable phasic DA &amp; NE firing, which can lead to euphoria and abuse (D)</p> Signup and view all the answers

All of the following medications are good alternatives for sleep in pt.s with insomnia EXCEPT?

<p>Exercise for 30 min before sleep (B)</p> Signup and view all the answers

Which brain region is involved in the reward center of the brain?

<p>Nucleus accumbens (D)</p> Signup and view all the answers

Amitriptyline is an acceptable sleep medication not typically used first line due to risk for falls. It is classified as?

<p>Tricyclic antidepressant (B)</p> Signup and view all the answers

All of the following should be monitored when RLS is suspected EXCEPT?

<p>CBC (D)</p> Signup and view all the answers

Which medication is a DA-NR reuptake inhibitor?

<p>Amphetamine (C)</p> Signup and view all the answers

Wellbutrin is a _______________?

<p>DA reuptake inhibitor (C)</p> Signup and view all the answers

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