Podcast
Questions and Answers
What is the primary cause of Peptic Ulcer Disease?
What is the primary cause of Peptic Ulcer Disease?
- High carbohydrate diet
- Chronic stress
- Excessive alcohol consumption
- H.pylori infection and NSAIDs (correct)
What symptom is typically associated with Peptic Ulcer Disease?
What symptom is typically associated with Peptic Ulcer Disease?
- Pain relieved by food or antacids (correct)
- Nausea and vomiting
- Persistent diarrhea
- Heartburn after meals
Which of the following complications is NOT associated with Peptic Ulcer Disease?
Which of the following complications is NOT associated with Peptic Ulcer Disease?
- Severe weight loss (correct)
- Hemorrhage
- Gastric outlet obstruction
- Perforation
In gastrointestinal bleeding, what does bright red blood indicate?
In gastrointestinal bleeding, what does bright red blood indicate?
What is NOT a sign of upper gastrointestinal bleeding?
What is NOT a sign of upper gastrointestinal bleeding?
What is a primary symptom of lower gastrointestinal bleeding?
What is a primary symptom of lower gastrointestinal bleeding?
Which of the following is a nursing assessment parameter for assessing cardiovascular status?
Which of the following is a nursing assessment parameter for assessing cardiovascular status?
What is classified as a primary cause of small bowel obstruction?
What is classified as a primary cause of small bowel obstruction?
What symptom is typically associated with intestinal obstruction?
What symptom is typically associated with intestinal obstruction?
The condition preventing the normal flow of chime through the intestine is known as?
The condition preventing the normal flow of chime through the intestine is known as?
Which clinical manifestation indicates a advanced state of intestinal obstruction?
Which clinical manifestation indicates a advanced state of intestinal obstruction?
In assessing lab values for gastrointestinal bleeding, which electrolyte should be monitored closely?
In assessing lab values for gastrointestinal bleeding, which electrolyte should be monitored closely?
What type of bowel obstruction is caused by conditions like malignancy?
What type of bowel obstruction is caused by conditions like malignancy?
What is a common cause of acute gastritis?
What is a common cause of acute gastritis?
Which symptom is typically associated with GERD?
Which symptom is typically associated with GERD?
What is a potential complication of Peptic Ulcer Disease (PUD)?
What is a potential complication of Peptic Ulcer Disease (PUD)?
Which statement about gastrointestinal bleeding is false?
Which statement about gastrointestinal bleeding is false?
What is a notable feature of chronic gastritis compared to acute gastritis?
What is a notable feature of chronic gastritis compared to acute gastritis?
Which of the following is NOT a typical symptom of GERD?
Which of the following is NOT a typical symptom of GERD?
What is a common characteristic of gastrointestinal hemorrhage?
What is a common characteristic of gastrointestinal hemorrhage?
Which medication could potentially exacerbate acute gastritis?
Which medication could potentially exacerbate acute gastritis?
Which factor specifically influences the development of Peptic Ulcer Disease?
Which factor specifically influences the development of Peptic Ulcer Disease?
What does the primary symptom of Peptic Ulcer Disease typically correlate with?
What does the primary symptom of Peptic Ulcer Disease typically correlate with?
Which complication of Peptic Ulcer Disease can result from scar tissue formation?
Which complication of Peptic Ulcer Disease can result from scar tissue formation?
How does the presence of an impairment in the mucosa barrier contribute to Peptic Ulcer Disease?
How does the presence of an impairment in the mucosa barrier contribute to Peptic Ulcer Disease?
What indicates a complication of gastrointestinal bleeding based on the blood’s appearance?
What indicates a complication of gastrointestinal bleeding based on the blood’s appearance?
Which of the following accurately describes a function of the liver?
Which of the following accurately describes a function of the liver?
Hepatitis A is primarily transmitted through which route?
Hepatitis A is primarily transmitted through which route?
What is a key assessment finding indicating liver dysfunction?
What is a key assessment finding indicating liver dysfunction?
Which statement accurately describes the pathophysiology of Hepatitis A?
Which statement accurately describes the pathophysiology of Hepatitis A?
What is a consequence of obstruction in hepatic circulation?
What is a consequence of obstruction in hepatic circulation?
What is a primary factor that may lead to lower gastrointestinal bleeding?
What is a primary factor that may lead to lower gastrointestinal bleeding?
Which symptom indicates acute cardiovascular issues during a nursing assessment?
Which symptom indicates acute cardiovascular issues during a nursing assessment?
Which condition is classified as a primary cause of large bowel obstruction?
Which condition is classified as a primary cause of large bowel obstruction?
In the context of intestinal obstruction, the term 'peristaltic rush' refers to what symptom?
In the context of intestinal obstruction, the term 'peristaltic rush' refers to what symptom?
What laboratory value requires careful monitoring during gastrointestinal bleeding assessment?
What laboratory value requires careful monitoring during gastrointestinal bleeding assessment?
Which of the following accurately describes acute gastritis?
Which of the following accurately describes acute gastritis?
What is a primary affect of chronic inflammation in gastritis?
What is a primary affect of chronic inflammation in gastritis?
Which statement accurately describes a type of bowel obstruction?
Which statement accurately describes a type of bowel obstruction?
Which symptom is most associated with a significant degree of intestinal obstruction?
Which symptom is most associated with a significant degree of intestinal obstruction?
In gastrointestinal dysfunction, which parameter is least likely to be assessed subjectively?
In gastrointestinal dysfunction, which parameter is least likely to be assessed subjectively?
Which condition is characterized by a backup of digestive contents due to a blockage?
Which condition is characterized by a backup of digestive contents due to a blockage?
During a nursing assessment, what does a decrease in urine output below 30 cc/hr potentially indicate?
During a nursing assessment, what does a decrease in urine output below 30 cc/hr potentially indicate?
What is a key clinical manifestation of hepatitis?
What is a key clinical manifestation of hepatitis?
Which symptom is most indicative of a lower gastrointestinal bleed?
Which symptom is most indicative of a lower gastrointestinal bleed?
What is the primary pathophysiological factor contributing to ascites development in cirrhosis?
What is the primary pathophysiological factor contributing to ascites development in cirrhosis?
Which of the following factors is most likely to trigger acute liver dysfunction?
Which of the following factors is most likely to trigger acute liver dysfunction?
Which clinical manifestation is least likely associated with hepatic encephalopathy?
Which clinical manifestation is least likely associated with hepatic encephalopathy?
Which assessment technique is crucial for evaluating gastrointestinal function?
Which assessment technique is crucial for evaluating gastrointestinal function?
What might indicate the development of bacterial peritonitis in a patient with ascites?
What might indicate the development of bacterial peritonitis in a patient with ascites?
Which of the following treatments is least likely to be effective in managing ascites?
Which of the following treatments is least likely to be effective in managing ascites?
Which factor among the following does NOT contribute to the pathophysiology of ascites?
Which factor among the following does NOT contribute to the pathophysiology of ascites?
Which clinical manifestation is most directly associated with fulminant viral hepatitis?
Which clinical manifestation is most directly associated with fulminant viral hepatitis?
What is a primary consequence of portal hypertension?
What is a primary consequence of portal hypertension?
Which mechanism is primarily responsible for jaundice resulting from hepatic obstruction?
Which mechanism is primarily responsible for jaundice resulting from hepatic obstruction?
What is often the first indicator of cirrhosis of the liver in a patient?
What is often the first indicator of cirrhosis of the liver in a patient?
Which condition is NOT typically a consequence of ascites?
Which condition is NOT typically a consequence of ascites?
What condition often leads to the development of Non-Alcoholic Steatohepatitis (NASH)?
What condition often leads to the development of Non-Alcoholic Steatohepatitis (NASH)?
Which symptom is commonly seen in patients with severe portal hypertension?
Which symptom is commonly seen in patients with severe portal hypertension?
Which of the following is a potential complication of cirrhosis?
Which of the following is a potential complication of cirrhosis?
Which sign is indicative of liver dysfunction associated with hepatobiliary disease?
Which sign is indicative of liver dysfunction associated with hepatobiliary disease?
Which of these is NOT a typical clinical manifestation seen in patients with hepatitis?
Which of these is NOT a typical clinical manifestation seen in patients with hepatitis?
What is a common clinical manifestation associated with a drop in Hemoglobin levels to 70-80 g/L?
What is a common clinical manifestation associated with a drop in Hemoglobin levels to 70-80 g/L?
Which type of anemia is characterized by small erythrocytes with insufficient hemoglobin?
Which type of anemia is characterized by small erythrocytes with insufficient hemoglobin?
What distinguishes Absolute Polycythemia from Relative Polycythemia?
What distinguishes Absolute Polycythemia from Relative Polycythemia?
Which of the following is a characteristic of Aplastic Anemia?
Which of the following is a characteristic of Aplastic Anemia?
What symptom is generally associated with Hemolytic Anemia?
What symptom is generally associated with Hemolytic Anemia?
What is a primary cause of thrombocytopenia in disseminated intravascular coagulation (DIC)?
What is a primary cause of thrombocytopenia in disseminated intravascular coagulation (DIC)?
Which symptom is associated with rapidly developing organ failure in DIC?
Which symptom is associated with rapidly developing organ failure in DIC?
What is a key laboratory finding in diagnosing thrombocytopenia?
What is a key laboratory finding in diagnosing thrombocytopenia?
Which type of anemia is characterized by large erythrocytes due to ineffective DNA synthesis?
Which type of anemia is characterized by large erythrocytes due to ineffective DNA synthesis?
What is the main consequence of the absence of intrinsic factor in pernicious anemia?
What is the main consequence of the absence of intrinsic factor in pernicious anemia?
Which treatment is essential for managing disseminated intravascular coagulation?
Which treatment is essential for managing disseminated intravascular coagulation?
What clinical manifestation indicates the rapid development of hemorrhage?
What clinical manifestation indicates the rapid development of hemorrhage?
What primary factors can lead to anemia?
What primary factors can lead to anemia?
Which of the following symptoms is commonly associated with hereditary hemochromatosis?
Which of the following symptoms is commonly associated with hereditary hemochromatosis?
What condition is characterized by an increased number of leukocytes in the blood?
What condition is characterized by an increased number of leukocytes in the blood?
Which of the following disorders results in a decrease in circulating leukocytes?
Which of the following disorders results in a decrease in circulating leukocytes?
What clinical manifestation is often seen in myelodysplastic syndrome (MDS)?
What clinical manifestation is often seen in myelodysplastic syndrome (MDS)?
Which term describes a malignant disorder characterized by uncontrolled proliferation of leukocytes?
Which term describes a malignant disorder characterized by uncontrolled proliferation of leukocytes?
Which type of alteration is indicated by the presence of eosinophilia?
Which type of alteration is indicated by the presence of eosinophilia?
What is a common result of granulocyte and monocyte alterations due to microbial invasion?
What is a common result of granulocyte and monocyte alterations due to microbial invasion?
What condition is characterized by a deficiency in healthy mature blood cell production?
What condition is characterized by a deficiency in healthy mature blood cell production?
Acute leukemia is characterized by what type of cells?
Acute leukemia is characterized by what type of cells?
Which condition involves an autosomal recessive disorder with tissue iron deposition?
Which condition involves an autosomal recessive disorder with tissue iron deposition?
Flashcards
Peptic Ulcer Disease (PUD)
Peptic Ulcer Disease (PUD)
A sore that develops in the lining of the stomach or duodenum, often caused by H. pylori or NSAIDs.
Cause of PUD
Cause of PUD
Common causes include bacteria (H. pylori) and nonsteroidal anti-inflammatory drugs (NSAIDs).
PUD Pathophysiology
PUD Pathophysiology
Acid environment weakens the stomach lining, acid diffuses, and erodes the mucosa layers.
PUD Symptom
PUD Symptom
Stomach pain, often relieved by food or antacids, is a primary symptom.
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Gastrointestinal Bleed (GI bleed)
Gastrointestinal Bleed (GI bleed)
Bleeding in the stomach or intestinal tract, potentially fatal if large and unaddressed.
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Lower GI Bleed
Lower GI Bleed
Bleeding in the lower part of the digestive tract, often presenting with bright red blood in stool.
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What are the typical symptoms of lower GI bleeding?
What are the typical symptoms of lower GI bleeding?
The main symptom is the presence of frank, bright red blood in the stool.
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Intestinal Obstruction
Intestinal Obstruction
A blockage in the intestines that prevents the normal flow of food and waste.
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Simple vs Functional Obstruction
Simple vs Functional Obstruction
Simple obstructions involve physical blockages, while functional obstructions involve problems with the muscles/nerves controlling the gut.
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Causes of Small Bowel Obstruction
Causes of Small Bowel Obstruction
Adhesions, hernias, and tumors can create blockages in the small intestine.
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Causes of Large Bowel Obstruction
Causes of Large Bowel Obstruction
Tumors, volvulus (twisting), and diverticulitis-related strictures can obstruct the large intestine.
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Clinical Manifestations of an Obstruction
Clinical Manifestations of an Obstruction
Symptoms like pain, vomiting, bloating, and abnormal bowel sounds are common.
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Treatment of Intestinal Obstruction
Treatment of Intestinal Obstruction
The approach depends on the cause, ranging from medications to surgery.
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Gastritis
Gastritis
Inflammation of the stomach lining. Causes include irritants and bacterial infection.
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Acute Gastritis
Acute Gastritis
Sudden onset gastritis caused by irritants like alcohol or spicy foods. May or may not have symptoms.
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Chronic Gastritis
Chronic Gastritis
Long-term gastritis that can damage the stomach lining and lead to atrophy (thinning). Often caused by bacteria like H. pylori.
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GERD (Gastroesophageal Reflux Disease)
GERD (Gastroesophageal Reflux Disease)
Acid reflux where stomach contents back up into the esophagus, causing heartburn and other symptoms.
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Obstruction/Ileus
Obstruction/Ileus
Blockage of the intestines, preventing the passage of food and waste. Can be caused by various factors.
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Hepatitis
Hepatitis
Inflammation of the liver, often caused by viral infections or alcohol abuse.
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PUD location
PUD location
Peptic ulcers usually form in the duodenum or stomach, with the duodenum being the most common site.
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PUD Cause?
PUD Cause?
H. pylori bacteria and NSAID medications are common causes of peptic ulcer disease.
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PUD Pain Relief?
PUD Pain Relief?
Peptic ulcer pain is usually relieved by eating or taking antacids.
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GI bleed location
GI bleed location
Bleeding in the digestive tract can happen anywhere, but color indicates location: bright red = closer, dark = further.
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PUD danger
PUD danger
Peptic ulcers can lead to serious complications: hemorrhage, obstruction, and even perforation.
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GERD
GERD
Gastroesophageal reflux disease. Acidic stomach contents back up into the esophagus, causing heartburn, a burning sensation in the chest.
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What are the potential consequences of untreated PUD?
What are the potential consequences of untreated PUD?
Untreated PUD can lead to complications such as bleeding, perforation (a hole in the stomach wall), and obstruction (blockage). Rarely, untreated PUD can lead to stomach cancer
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What causes gastrointestinal bleeding?
What causes gastrointestinal bleeding?
Bleeding in the gastrointestinal tract (GI tract) can be caused by various factors, including ulcers (PUD), gastritis, tumors, and even trauma like an injury to the gut.
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What is an intestinal obstruction?
What is an intestinal obstruction?
A blockage in the intestines that prevents the normal flow of food and waste. Can be caused by various factors including adhesions, tumors, and twisting of the intestines.
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What is hepatitis?
What is hepatitis?
Inflammation of the liver. Often caused by viral infections such as hepatitis A, B, and C, or alcohol abuse.
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What are the differences in the pathophysiology of gastric/intestinal disorders and liver disorders?
What are the differences in the pathophysiology of gastric/intestinal disorders and liver disorders?
Gastric/intestinal disorders primarily involve inflammation, ulcers, and obstruction of the digestive tract. Liver disorders involve inflammation, damage, and dysfunction of the liver, a vital organ for filtering blood and producing essential substances.
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Liver's Role
Liver's Role
The liver plays a crucial role in various bodily functions including bile production, metabolism of bilirubin, nutrients, and drugs, detoxification, and storage of minerals.
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Hepatitis A Transmission
Hepatitis A Transmission
Hepatitis A is spread through the fecal-oral route, mainly via contaminated food, water, and blood.
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Hepatitis A Damage
Hepatitis A Damage
Hepatitis A causes inflammation and damage to liver tissue due to cytotoxic cytokines and natural killer cells that destroy infected hepatocytes.
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Hepatitis A Symptoms
Hepatitis A Symptoms
Hepatitis A usually presents with symptoms like fatigue, jaundice, abdominal pain, loss of appetite, and dark urine.
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Hepatitis A Incubation
Hepatitis A Incubation
The incubation period for Hepatitis A is typically 2-7 weeks, which means the virus may exist unnoticed for some time before causing symptoms.
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Lower GI Bleed Symptom
Lower GI Bleed Symptom
The primary symptom of a lower GI bleed is the presence of bright red blood in the stool.
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Intestinal Obstruction - What is it?
Intestinal Obstruction - What is it?
An intestinal obstruction is a blockage in the intestines that prevents the normal flow of food and waste.
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Small Bowel Obstruction - Causes
Small Bowel Obstruction - Causes
Common causes of small bowel obstruction include adhesions, hernias, and tumors.
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Large Bowel Obstruction - Causes
Large Bowel Obstruction - Causes
Tumors, volvulus (twisting of the intestine), and diverticulitis-related strictures can obstruct the large intestine.
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Obstruction Symptoms
Obstruction Symptoms
Common symptoms of intestinal obstruction include pain, vomiting, bloating, and abnormal bowel sounds.
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Obstruction Treatment
Obstruction Treatment
Treatment for intestinal obstruction depends on the cause and can range from medications to surgery.
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Obstruction Clinical Manifestations
Obstruction Clinical Manifestations
Symptoms of obstruction depend on the severity and duration of the blockage. They can be sudden and severe, including pain, vomiting, and distention.
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Ascites
Ascites
Fluid buildup in the peritoneal cavity, often caused by cirrhosis, heart failure, or cancer. It disrupts normal physiological functions.
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Ascites Causes
Ascites Causes
Common causes include portal hypertension, low albumin levels, dilated blood vessels in the gut, and fluid retention by kidneys.
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Ascites Manifestations
Ascites Manifestations
Symptoms include abdominal swelling, weight gain, shortness of breath, and leg swelling. Bacterial infection can also occur.
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Hepatic Encephalopathy
Hepatic Encephalopathy
A brain disorder caused by liver dysfunction, characterized by confusion, tremors, and altered consciousness. It can be life-threatening.
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Hepatic Encephalopathy Pathophysiology
Hepatic Encephalopathy Pathophysiology
High ammonia and GABA levels in the brain contribute to neurologic symptoms. This can happen quickly and become dangerous.
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Fulminant Viral Hepatitis
Fulminant Viral Hepatitis
A severe liver disease characterized by rapid and extensive liver cell damage, potentially caused by Hepatitis B, C, or Tylenol overdose.
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Jaundice: What causes it?
Jaundice: What causes it?
Yellowing of the skin and whites of the eyes due to a buildup of bilirubin in the blood, caused by problems with bilirubin processing in the liver or blockage of bile flow.
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Portal Hypertension
Portal Hypertension
High blood pressure in the portal vein system, caused by resistance to blood flow through the liver, often due to cirrhosis, hepatitis, or blockages.
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Varices
Varices
Swollen, enlarged veins in the esophagus and stomach, often developing due to portal hypertension, which can cause life-threatening bleeding.
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NAFLD vs NASH
NAFLD vs NASH
NAFLD: Fatty liver disease without alcohol use. NASH: More serious, with inflammation and scarring of the liver. Both linked to obesity, high cholesterol, and diabetes.
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Cirrhosis of the Liver
Cirrhosis of the Liver
Scarring and damage to the liver that disrupts its structure and function, often caused by chronic hepatitis, alcoholism, or fatty liver disease.
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Hepatorenal Syndrome
Hepatorenal Syndrome
A complication of advanced liver disease where the kidneys suddenly fail due to impaired blood flow and fluid retention.
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What are the clinical manifestations of cirrhosis?
What are the clinical manifestations of cirrhosis?
Symptoms of cirrhosis include abnormal liver function tests, fatigue, abdominal pain, weight loss, jaundice, edema, ascites, portal hypertension, and potentially hepatic encephalopathy or hepatorenal syndrome.
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Microcytic-Hypochromic Anemia
Microcytic-Hypochromic Anemia
Anemia characterized by small, pale red blood cells with reduced hemoglobin content.
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Sideroblastic Anemia
Sideroblastic Anemia
Anemia caused by ineffective iron uptake, leading to abnormal hemoglobin synthesis.
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Aplastic Anemia
Aplastic Anemia
Anemia due to insufficient red blood cell production, often caused by an autoimmune attack on the bone marrow.
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Polycythemia Vera
Polycythemia Vera
A condition characterized by an abnormal increase in red blood cell production due to an overproduction of bone marrow stem cells.
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Relative Polycythemia
Relative Polycythemia
A condition where there is an apparent increase in red blood cells, but the actual number is normal. This is caused by a decrease in plasma volume, making the red blood cells appear more concentrated.
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Polycythemia
Polycythemia
A condition characterized by an abnormally high red blood cell count, leading to increased blood viscosity and potential complications like blood clots.
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Hereditary Hemochromatosis
Hereditary Hemochromatosis
A genetic disorder causing excessive iron absorption, leading to iron buildup in tissues and potential organ damage.
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What are the symptoms of Hemochromatosis?
What are the symptoms of Hemochromatosis?
Symptoms include fatigue, abdominal pain, joint pain, impotence, hepatomegaly, abnormal liver enzymes, bronzed skin, diabetes, and heart enlargement.
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Leukocytosis
Leukocytosis
An increase in white blood cells in the blood, often indicating an infection or inflammation.
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Leukopenia
Leukopenia
A decrease in white blood cells in the blood, increasing susceptibility to infections.
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Neutrophilia
Neutrophilia
An increase in neutrophils, a type of white blood cell, often seen in early stages of infection or inflammation.
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Neutropenia
Neutropenia
A decrease in neutrophils, increasing the risk of severe infections.
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Myelodysplastic Syndrome (MDS)
Myelodysplastic Syndrome (MDS)
A group of disorders where the bone marrow fails to produce enough healthy blood cells, leading to various complications.
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Leukemia
Leukemia
Cancer of the blood and bone marrow, characterized by uncontrolled proliferation of abnormal white blood cells.
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Acute Leukemia
Acute Leukemia
A fast-growing type of leukemia characterized by immature white blood cells (blasts) and a rapid onset.
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Disseminated Intravascular Coagulation (DIC)
Disseminated Intravascular Coagulation (DIC)
A life-threatening condition where the body's clotting system is overactivated, leading to widespread clotting in small blood vessels and excessive bleeding.
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DIC Symptoms
DIC Symptoms
DIC can present with both bleeding and clotting problems, causing rapid development of hemorrhage, shock, low blood pressure, and organ failure due to microvascular blockages.
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DIC Diagnosis
DIC Diagnosis
Diagnosis of DIC is based on clinical presentation, laboratory tests like prolonged clotting time, low platelet count (thrombocytopenia), and elevated D-dimer.
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Anemia: Definition
Anemia: Definition
A condition characterized by a deficiency in red blood cells (erythrocytes) or hemoglobin, leading to reduced oxygen-carrying capacity of the blood.
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Anemia: Types
Anemia: Types
Anemia can be classified by its cause: altered production, blood loss, increased destruction of red blood cells, or a combination. Anemia can also be classified by changes in red blood cell size, shape, or substance.
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Macrocytic-Normochromic Anemia
Macrocytic-Normochromic Anemia
This type of anemia is characterized by large red blood cells (erythrocytes) due to ineffective DNA synthesis, often caused by Vitamin B12 or folate deficiency.
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Pernicious Anemia
Pernicious Anemia
Caused by a lack of intrinsic factor, a protein needed to absorb Vitamin B12 from the diet, leading to a deficiency and impaired DNA synthesis in red blood cells.
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Folate Deficiency Anemia
Folate Deficiency Anemia
Occurs when there's insufficient folate (folic acid) in the body, which is crucial for DNA synthesis and red blood cell production.
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Alterations in Gastrointestinal Function
- This presentation covers alterations in gastrointestinal function, specifically the anatomy and physiology of the GI system and how dysfunction affects the body.
- It also outlines the pathophysiology of various conditions, including:
- Gastritis.
- Gastroesophageal Reflux Disease (GERD).
- Peptic Ulcer Disease (PUD).
- Gastrointestinal (Upper and Lower) Bleed.
- Obstruction/Ileus.
- Hepatitis.
- Acute Liver Dysfunction.
- Hepatic Encephalopathy.
- Cholelithiasis and Cholecystitis.
- Fulminant Hepatic Failure.
- The presentation emphasizes prioritizing conditions related to nursing assessment and clinical manifestations.
Abdominal Assessment
- Subjective Data:
- Appetite.
- Dysphagia.
- Food intolerance.
- Abdominal pain.
- Nausea/vomiting.
- Bowel habits.
- Past abdominal history.
- Medications.
- Nutritional assessment.
- Objective Data:
- Inspect (contour, symmetry, umbilicus, skin, hair, movement, and demeanor).
- Auscultate (hyperactive, hypoactive, and absent bowel sounds).
- Percuss.
- Palpate.
Objectives
- Students will identify at least five common issues in the GI system.
- Describe dysfunction associated with the stomach, intestines, and liver.
- Explain three differences in pathophysiology and assessment of stomach/intestinal and liver systems.
- Apply previously learned concepts to GI/liver dysfunction through critical thinking exercises.
Stomach and Intestinal Dysfunction
- Gastritis (inflammation of the stomach):
- Causes: acute (local irritants) and chronic.
- Chronic can lead to atrophy of the glandular epithelium.
- H. pylori is a common cause.
- Pathophysiology (Gastritis):
- Breakdown of the gastric mucosal barrier.
- Acid reflux into the mucosal layer.
- Resulting tissue edema, disrupted capillary walls, loss of plasma, and possible hemorrhage.
- Clinical Manifestations (Gastritis):
- Anorexia, nausea, vomiting, epigastric tenderness, fullness.
- Hemorrhage is commonly associated with alcohol abuse.
- Causes (Gastritis):
- Drugs (aspirin, corticosteroids, NSAIDs).
- Diet (spicy, irritating foods).
- Microorganisms (H. pylori, Salmonella).
- Environmental factors (radiation, smoking).
- Pathophysiological conditions (burns, large hiatal hernia, physiological stress, reflux of bile, renal failure).
Gastroesophageal Reflux Disease (GERD)
- Pathophysiology: Backflow of stomach contents into the esophagus, regulated by a sphincter at the stomach entrance. Transient relaxation occurs after meals, particularly with fatty foods.
- Clinical Manifestations: epigastric pain or heartburn, sometimes belching, chest pain. Also, respiratory symptoms (wheezing, coughing, dyspnea), and otolaryngologic symptoms (hoarseness, sore throat, globus sensation, choking).
- Nursing Assessment: Assess neuro (dysphagia, PQRST pain), cardiovascular (chest pain, BP changes), respiratory (sore throat, hoarseness, wheezing, coughing), and gastrointestinal (nutritional status, painful swallowing, heartburn, nausea/vomiting, weight loss).
Peptic Ulcer Disease (PUD)
- Pathophysiology: Formation of ulcers on the stomach and/or duodenum, often in the presence of acid environment. Damage to mucosa barrier leads to acid backflow and tissue deterioration..
- Clinical Manifestations: Primary symptom is pain typically on empty stomach; relieved by food or antacids.
- Causes: often by H. pylori or NSAIDs.
- Complications includes: hemorrhage, gastric outlet obstruction, perforation, which can lead to peritonitis.
Gastrointestinal Bleed
- Can occur anywhere in the GI tract (UGIB or LGIB).
- Site of bleeding is indicated by color and texture (bright red to tarry black/melena).
- Upper GI often involves coffee-ground material (partially digested) or bright red blood. Brighter color indicates source is nearer the opening; darker color indicates source is further downstream (eg, hemorrhage in duodenum).
- Lower GI involved with frank red blood.
- Think EMERGENCY situation.
Obstruction/Ileus
- An obstruction prevents the normal passage of chyme through the intestines.
- Loss of intestinal motility.
- Primary causes of small bowel obstruction: adhesions, hernias, tumors
- Primary causes of large bowel obstruction: malignancy, volvulus, strictures related to diverticulitis.
Liver and Gallbladder Dysfunction
- Liver Structure and Function - Contains multiple lobes and is vital for many physiological functions.
- Hepatitis A - Causes widespread inflammation of liver tissue, results from cytotoxic cytokines, and natural killer cells lysing infected hepatocytes. This leads to necrosis and inflammation, often via a contaminated water/food fecal oral route.
- Fulminant Viral Hepatitis - Severe liver impairment or necrosis; often presents after initial symptoms of hepatitis, involves symptoms like anorexia, vomiting, abdominal pain, jaundice, ascites, and gastrointestinal bleeding.
- Jaundice - A possible consequence of liver dysfunction. It results from the inability to process or excrete bilirubin correctly.
- Portal Hypertension - Abnormally high blood pressure in the portal venous system, caused by resistance to portal blood flow.
- Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH)– conditions where fat infiltrates hepatocytes, which can lead to liver damage and potentially liver failure. If not addressed effectively, this condition can lead to scarring and irreversible damage to the liver.
- Cirrhosis - Irreversible inflammatory and fibrotic liver disease and necrosis of liver cells. Scarring of the liver that damages its function is a result..
- Ascites - Accumulation of fluid in the peritoneal cavity, often due to increased pressure in the lymphatic system and capillaries
- Hepatic Encephalopathy: A complex neurologic syndrome characterized by impaired cognitive function, often progressing to confusion, flapping tremors, stupor, convulsions, and coma.
- Ammonia and GABA levels may play a role in its progression
Gallbladder Disorders
- Cholelithiasis - Formation of gallstones due to impaired cholesterol, bilirubin, and bile salt metabolism and imbalances.
- Can present as asymptomatic, vague symptoms, or biliary colic (pain from contraction of the gallbladder).
- Cholecystitis - Inflammation of the gallbladder, often caused by gallstones obstructing the cystic duct.
- Diagnostic Tests: ERCP (Endoscopic Retrograde Cholangiopancreatography), plain x-rays, ultrasound, and scintigraphy (HIDA).
Key Points to Remember
- Students can perform a comprehensive abdominal assessment while understanding the physiological landmarks relevant to GI function.
- They can identify the "why" behind GI assessments and relate them to multiple organ systems.
- Students can apply V/Q mismatching concepts to various respiratory conditions and understand the pathophysiology, clinical manifestations, and nursing assessment related to GI and liver dysfunction.
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