NUR 226 - Renal Drugs Flashcards

Questions and Answers

What is the therapeutic effect of Epogen (EPO)?

Treatment for anemia

How is Epogen (EPO) administered?

Intramuscularly

Intravenously or Subcutaneously (correct)

Topically

Orally

What is the expected pharmacological action of Furosemide (Lasix)?

Acts on ascending loop of Henle to block reabsorption

What are the therapeutic uses of Furosemide (Lasix)?

Edematous states Signup and view all the answers

What is the medication administration guideline for Furosemide (Lasix) orally?

60 min onset, 8 hr duration, 20-80 mg/day Signup and view all the answers

What is the expected pharmacological action of hydrochlorothiazide (HydroDIURIL)?

Increases renal excretion of sodium, chloride, potassium, and water Signup and view all the answers

What is a common therapeutic use of hydrochlorothiazide (HydroDIURIL)?

Essential hypertension Signup and view all the answers

What classification does Furosemide (Lasix) belong to?

High ceiling loop diuretic Signup and view all the answers

What classification does hydrochlorothiazide (HydroDIURIL) belong to?

Thiazide diuretic and antihypertensive Signup and view all the answers

What classification does Spironolactone (Aldactone) belong to?

Aldosterone antagonist (potassium-sparing diuretic) Signup and view all the answers

What is the expected pharmacological action of Spironolactone (Aldactone)?

Blocks aldosterone in the distal nephron, causing retention of K and increased excretion of Na Signup and view all the answers

What are the therapeutic uses of Spironolactone (Aldactone)?

Edematous states Signup and view all the answers

What classification does Triamterene (Dyrenium) belong to?

Non-aldosterone antagonists (potassium-sparing diuretics) Signup and view all the answers

What is the expected pharmacological action of Triamterene (Dyrenium)?

Disrupts Na and K exchange in the distal nephron Signup and view all the answers

What are the therapeutic uses of Triamterene (Dyrenium)?

Hypertension Signup and view all the answers

What classification does calcium acetate (Phoslo) belong to?

Calcium-containing phosphate binders Signup and view all the answers

What is the expected pharmacological action of calcium acetate (Phoslo)?

Combines with phosphorus in meals and is excreted in stool Signup and view all the answers

What are the therapeutic uses of calcium acetate (Phoslo)?

Calcium supplement Signup and view all the answers

What nursing interventions are important for calcium acetate (Phoslo)?

Do not give to patients on dialysis Signup and view all the answers

What classification does mannitol (Osmitrol) belong to?

Osmotic diuretics Signup and view all the answers

What is the expected pharmacological action of mannitol (Osmitrol)?

Promotes diuresis by creating osmotic force within the lumen of the nephron Signup and view all the answers

What are the therapeutic uses of mannitol (Osmitrol)?

Prophylaxis of renal failure Signup and view all the answers

What classification does sevelamer hydrochloride (Renagel) belong to?

Calcium-free phosphate binders Signup and view all the answers

What is the expected pharmacological action of sevelamer hydrochloride (Renagel)?

Binds and eliminates phosphate, preventing absorption Signup and view all the answers

What are the therapeutic uses of sevelamer hydrochloride (Renagel)?

Treat high phosphorus levels Signup and view all the answers

What classification does Alucap belong to?

Aluminum-containing phosphate binders Signup and view all the answers

What is the expected pharmacological action of Alucap?

Binds phosphate in the GI tract Signup and view all the answers

What are the therapeutic uses of Alucap?

Antacid Signup and view all the answers

What is the classification for Kayexalate?

K+ ion exchange resin Signup and view all the answers

What is the expected pharmacological action of Kayexalate?

Binds with K+, prevents reabsorption, excreted in stool Signup and view all the answers

What is the classification for Finasteride (Proscar)?

Hormonal therapy for BPH Signup and view all the answers

What are the expected pharmacological actions of Finasteride (Proscar)?

Suppresses glandular cell activity and decreases the size of the prostate, lowers DHT Signup and view all the answers

What are the therapeutic uses of Finasteride (Proscar)?

Prevention of prostate growth Signup and view all the answers

Study Notes

Epogen (EPO)

Synthetic erythropoietin used for treating anemia.
Administered via subcutaneous (SQ) or intravenous push (IVP) three times a week; dosing varies based on hematocrit (Hct) levels.

Furosemide (Lasix)

High ceiling loop diuretic that blocks reabsorption in the ascending loop of Henle.
Treats pulmonary edema, mild edematous states, and hypertension.
Oral onset is 60 minutes with an 8-hour duration; intravenous onset is 5 minutes with a 2-hour duration.

Hydrochlorothiazide (HydroDIURIL)

Thiazide diuretic working in the early distal convoluted tubule.
Increases renal excretion of sodium, chloride, potassium, and water while elevating uric acid and glucose levels.
Primarily used for essential hypertension and edema.

Spirolactone (Aldactone)

Aldosterone antagonist and potassium-sparing diuretic.
Blocks aldosterone in the distal nephron leading to potassium retention and sodium excretion.
Used primarily for hypertension, mild edematous states, and heart failure.

Triamterene (Dyrenium)

Non-aldosterone antagonist and potassium-sparing diuretic.
Disrupts sodium and potassium exchange in the distal nephron.
Utilized for primary hypertension treatment and edema.

Calcium Acetate (Phoslo)

Calcium-containing phosphate binder that combines with phosphorus during meals for excretion in stool.
Treats high phosphate levels and replaces calcium deficiency.
Contraindicated in patients on dialysis.

Mannitol (Osmitrol)

Osmotic diuretic that promotes diuresis by creating osmotic force within the nephron.
Indicated for prophylaxis of renal failure and reduction of intracranial and intraocular pressure.

Sevelamer Hydrochloride (Renagel)

Calcium-free phosphate binder that binds to phosphate to prevent absorption.
Used to manage high phosphorus levels.

Alucap

Aluminum-containing phosphate binder that binds phosphate in the gastrointestinal tract.
Functions as an antacid and helps lower serum phosphate levels.

Kayexalate

Potassium ion exchange resin that binds potassium to prevent reabsorption, allowing excretion in stool.

Finasteride (Proscar)

Hormonal therapy for benign prostatic hyperplasia (BPH).
Suppresses glandular cell activity, decreases prostate size, and lowers dihydrotestosterone (DHT) levels.
Prevents further growth of the prostate in BPH patients.

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Description

Test your knowledge on renal pharmacology with these flashcards focusing on key drugs such as Epogen and Furosemide. Each card provides essential therapeutic effects, administration routes, and expected pharmacological actions to help you master the material. Ideal for nursing students preparing for exams in NUR 226.