NUR 131 Medical-Surgical Nursing: Cancer Overview

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Questions and Answers

What is the most characteristic manifestation of colon cancer?

  • Weight loss
  • Persistent fatigue
  • Alteration in bowel habits (correct)
  • Change in body temperature

Which mutation is primarily associated with oncogenesis?

  • Tumor suppressor genes (correct)
  • Cell death genes
  • Cell cycle checkpoint genes
  • DNA repair genes

What may a change in bladder habits signify?

  • Colon cancer
  • Kidney stones
  • Liver disease
  • Bladder or prostate cancer (correct)

What causes a sore that does not heal?

<p>Tumor-induced impaired circulation (A)</p> Signup and view all the answers

What is a common consequence of impaired circulation due to tumors?

<p>Tissue necrosis and ulceration (C)</p> Signup and view all the answers

What type of genes are involved in cellular differentiation?

<p>Cellular differentiation genes (D)</p> Signup and view all the answers

Which of the following may indicate unusual discharge?

<p>Erosion of capillaries (C)</p> Signup and view all the answers

Which type of cancer is associated with Hereditary retinoblastoma?

<p>Retinoblastoma (B)</p> Signup and view all the answers

Which of the following gene mutations is directly related to cellular senescence?

<p>Cellular senescence genes (C)</p> Signup and view all the answers

What does the presence of oncogenes indicate about cancer risk?

<p>It determines the risk or percentage of developing cancer. (D)</p> Signup and view all the answers

Which of the following conditions is primarily associated with Wilms' tumor?

<p>Li-Fraumeni Syndrome (C)</p> Signup and view all the answers

What role do proto-oncogenes play in normal cell growth?

<p>They encode components of normal growth-control pathways. (D)</p> Signup and view all the answers

Xeroderma pigmentosum is primarily associated with which type of cancer?

<p>Skin cancer (A)</p> Signup and view all the answers

Which type of cancer does Familial Adenomatous Polyposis predispose an individual to?

<p>Colon and rectal cancer (C)</p> Signup and view all the answers

What type of cancer does Fanconi’s aplastic anemia primarily involve?

<p>Liver cancer (C)</p> Signup and view all the answers

What characteristic differentiates a cancer cell from a normal cell?

<p>Mutated or damaged oncogenes (D)</p> Signup and view all the answers

What characterizes tissue that grows by expansion without infiltrating surrounding tissues?

<p>The tissue is usually encapsulated (B)</p> Signup and view all the answers

What is a key feature that differentiates metastasis from local growth?

<p>It spreads through blood and lymphatic channels (B)</p> Signup and view all the answers

What effect does hyperplasia have on tissue?

<p>It results in a larger than usual number of cells (A)</p> Signup and view all the answers

What is the relationship between the rate of growth and anaplasia in tissues?

<p>Higher anaplasia correlates with faster growth (A)</p> Signup and view all the answers

Which of the following is NOT typically associated with generalized effects of tissue growth?

<p>Localized swelling (D)</p> Signup and view all the answers

What is a common outcome of dysplasia in tissues?

<p>Loss of normal tissue arrangement and cell structure (A)</p> Signup and view all the answers

Which of the following describes the growth rate of a tissue with highly anaplastic cells?

<p>Fast and erratic (C)</p> Signup and view all the answers

What condition may require treatment due to potentially becoming malignant?

<p>Dysplasia (B)</p> Signup and view all the answers

What is a local symptom of cancer?

<p>Lumps or swelling (A)</p> Signup and view all the answers

Which symptom is categorized as a metastatic symptom?

<p>Lymphadenopathy (A)</p> Signup and view all the answers

Which of the following is a systemic symptom of cancer?

<p>Anemia (A)</p> Signup and view all the answers

What type of pain history is most crucial to determine in cancer management?

<p>Location and frequency of pain (A)</p> Signup and view all the answers

What symptom can indicate an advanced stage of cancer?

<p>Painless initial swelling (D)</p> Signup and view all the answers

Which nursing care concern is related to altered nutrition in cancer patients?

<p>Risk for fluid volume deficit (A)</p> Signup and view all the answers

What should a nurse do regarding a patient's report of pain?

<p>Believe the patient's report (A)</p> Signup and view all the answers

Which of the following is not considered a systemic symptom of cancer?

<p>Ulceration (A)</p> Signup and view all the answers

What characterizes adenocarcinoma?

<p>It arises from epithelial cells that produce fluids or mucus. (C)</p> Signup and view all the answers

Which type of cancer is least treatable if it has progressed?

<p>Adenocarcinoma (A)</p> Signup and view all the answers

Which type of cancer is primarily associated with skin surface issues?

<p>Basal cell carcinoma (D)</p> Signup and view all the answers

Squamous cell carcinoma primarily affects which type of cells?

<p>Epithelial cells beneath the skin surface (C)</p> Signup and view all the answers

Transitional cell carcinoma is most commonly found in which type of organ?

<p>Organs that undergo expansion (C)</p> Signup and view all the answers

What signifies the disease process affecting cancerous cells?

<p>Cells ignore growth-regulating signals. (A)</p> Signup and view all the answers

Basal cell carcinoma is primarily associated with which of the following traits?

<p>It begins in the basal layer of the epidermis. (C)</p> Signup and view all the answers

Which cancer type is least typically associated with abnormalities in organ output?

<p>Basal cell carcinoma (A)</p> Signup and view all the answers

What measure can be used to help manage anxiety in patients undergoing cancer treatment?

<p>Encouraging the use of relaxation techniques (D)</p> Signup and view all the answers

Which of the following is a non-pharmacological comfort measure for patients experiencing discomfort?

<p>Diversional activities like music or television (C)</p> Signup and view all the answers

What is a potential risk for patients undergoing therapies such as chemotherapy?

<p>Risk for impaired oral mucous membrane (C)</p> Signup and view all the answers

Which technique is NOT identified for managing pain in cancer patients?

<p>Ignoring patient feedback on pain (D)</p> Signup and view all the answers

What is important for nurses to provide to patients about surgical therapies?

<p>Educative information on what to expect (D)</p> Signup and view all the answers

Which of the following is a psychosocial nursing care focus?

<p>Anticipatory grieving support (A)</p> Signup and view all the answers

What type of care should be given to address family processes during cancer treatment?

<p>Addressing risk for altered family process (D)</p> Signup and view all the answers

When managing constipation in patients, what is an appropriate intervention?

<p>Providing non-pharmacological measures (B)</p> Signup and view all the answers

Flashcards

Cancer

A disease process whereby cells proliferate abnormally, ignoring growth-regulating signals in the environment surrounding the cell.

Adenocarcinoma

Cancer that forms in epithelial cells that produce fluids or mucus. Most common: breast, colon, and prostate cancer.

Basal Cell Carcinoma

Cancer that begins in the lower or basal (base) layer of the epidermis. Ex: skin cancer. It is more treatable than adenocarcinoma if there is no progression of cancer yet.

Squamous Cell Carcinoma

Cancer that forms in squamous cells, which are epithelial cells that lie just beneath the outer surface of the skin. Ex: tongue, stomach, intestine, bladder, kidney.

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Transitional Cell Carcinoma

Cancer that forms in a type of epithelial tissue called transitional epithelium or urothelium. Most commonly found in organs that expand.

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Genetic Material Depletion

The depletion of genetic material

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Renal Tubule Damage

Manifestation of SOB & problem in output of patient because of the damage in the renal tubules.

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Epithelial Cell Formation

They are formed by epithelial cells.

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Mode of Growth: Expansion

A type of tissue growth where cells grow by expansion and do not infiltrate surrounding tissues. It usually remains encapsulated.

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Mode of Growth: Infiltration

A type of tissue growth where cells grow at the periphery and infiltrate surrounding tissues, destroying them.

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Metastasis: Does not spread

When a tumor does not spread to other parts of the body.

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Metastasis: Spreads

When a tumor gains access to blood and lymphatic channels, spreading to other parts of the body.

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Hyperplasia

Excessive cell division leading to a larger than normal number of cells. Often localized with effects such as hand calluses.

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Dysplasia

An abnormal type of excessive cell proliferation characterized by loss of normal tissue arrangement and cell structure. Cells can revert back to normal behavior, but sometimes become malignant.

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Fast Growing Cells (Examples)

Fast-growing cells seen in skin, nails, and hair due to their access to nutrients and blood vessels.

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General Effects: Localized

Causes localized effects, meaning the impact only affects the immediate area of the tumor.

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Oncogenes

Genes that, when damaged, can lead to uncontrolled cell growth and potentially cancer development.

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Proto-oncogenes

The precursor of cancer cells. They promote the growth of cancer cells, thus increasing the risk of cancer.

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Cancer Risk

A condition that increases the likelihood of developing cancer.

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Cancer Cell

A condition where the normal growth control pathway is disrupted, leading to abnormal cell growth.

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Hereditary Retinoblastoma

A condition that increases the risk of developing retinoblastoma, a type of eye cancer.

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Xeroderma Pigmentosum

A condition that increases the risk of developing skin cancer.

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Wilm's Tumor

A condition that increases the risk of developing kidney cancer.

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Li-Fraumeni Syndrome

A condition that increases the risk of developing various cancers, including sarcomas, brain tumors, breast cancer, and leukemia.

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What is acute pain?

A unpleasant sensory and emotional experience arising from actual or potential tissue damage or described in terms of such damage.

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How to prepare patients for treatments?

Provide information to patients and SO about what to expect from treatments like surgery, radiation, chemotherapy, biotherapy.

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What are some non-pharmacological comfort measures?

Use of non-pharmacological measures like massage, repositioning, backrubs, and diversional activities such as music, television, etc., to provide comfort to patients.

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What are some ways to help patients manage stress?

Encourage stress management practices like relaxation techniques, visualization, guided imagery, biofeedback, laughter, music, aromatherapy, and therapeutic touch.

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How can we provide cutaneous stimulation?

Provide cutaneous stimulation, such as heat or cold, or massage to soothe and comfort patients.

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What are the challenges to cancer pain management?

Be aware of factors that might hinder effective cancer pain management, both within the patient and the healthcare system.

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How to monitor and adjust pain relief?

Evaluate the effectiveness of pain relief and control at regular intervals, and adjust the medication regimen as needed.

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What causes rapid metabolism in cancer patients?

Rapid cell division leads to faster metabolism in cancer patients.

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What are local symptoms of cancer?

Symptoms that are restricted to the primary cancer site. Examples include lumps, swelling, bleeding, ulceration, and pain. Initial swelling is often painless.

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What are metastatic symptoms of cancer?

Symptoms that occur when cancer spreads to other parts of the body.

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What are systemic symptoms of cancer?

Symptoms that are a result of the cancer's effects on the body, but aren't caused by direct tumor growth or spread.

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What is lymphadenopathy?

Swollen lymph nodes, often a sign of cancer spread.

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What is hepatomegaly?

An enlarged liver, often a sign of cancer spread.

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What is splenomegaly?

An enlarged spleen, often a sign of cancer spread.

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What does pain or fractures indicate in cancer patients?

Pain or bone fractures caused by cancer spreading to the bones.

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What is a common sign of colon cancer?

A change in bowel habits, such as constipation or diarrhea, is a common sign of colon cancer.

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What might changes in bladder habits indicate?

Changes in bladder habits, like needing to urinate more frequently or having difficulty emptying the bladder, can signal bladder or prostate cancer.

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What can a non-healing sore signal?

A sore that doesn't heal can be a sign of cancer as tumor growth disrupts blood flow and oxygen to the area.

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What might unusual bleeding or discharge indicate?

Unusual bleeding or discharge, often related to impaired blood flow and oxygenation, can be a sign of cancer. It can occur due to tissue damage, ulceration, or erosion of capillaries.

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What role do oncogenes play in cancer development?

Mutations in oncogenes can contribute to cancer by promoting uncontrolled cell growth. These genes act like 'accelerators' for cell division.

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How do tumor suppressor gene mutations contribute to cancer?

Mutations in tumor suppressor genes can lead to cancer by removing the brakes on cell growth, allowing abnormal cells to proliferate unchecked.

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What is the role of DNA repair genes in cancer prevention?

Mutations in DNA repair genes can increase the risk of cancer by making cells more susceptible to DNA damage and errors during cell division.

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What do mutations in cell cycle checkpoints contribute to?

Mutations in cell cycle checkpoint genes can lead to cancer by allowing damaged cells to bypass checkpoints and continue dividing, increasing the accumulation of genetic errors.

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Study Notes

NUR 131 Medical-Surgical Nursing 1: TranxCN: Cancer Release

  • This is a set of guidelines specifically intended for nursing students at De La Salle Medical and Health Sciences Institute.
  • The TranxCN is not for sale.
  • Any reproduction, imitation, alteration, or tampering is strictly prohibited.
  • Failure to follow the guidelines will result in the immediate termination of access.
  • TranxCN is not intended to replace materials provided by the college.
  • The College of Nursing faculty/professors are not liable for any errors.

Concept of Cellular Aberration: An Introduction

  • Cancer is a disease involving uncontrolled growth of body cells.
  • Cancer cells fail to respond to signals that control normal growth.
  • Cancer cells ignore growth-regulating signals in the surrounding environment.
  • Genetic material is depleted.

Naming Cancers

  • Prefixes are used to name cancers.
  • Example: Adeno- refers to glands.

Types of Cancer

  • Carcinoma : Most common cancer type; formed by epithelial cells.
  • Adenocarcinoma : Develops in epithelial cells that produce fluids or mucus (e.g., breast, colon, prostate).
  • Basal Cell Carcinoma : Begins in the lower basal layer of epidermis (e.g., skin cancer).
  • Squamous Cell Carcinoma : Forms in squamous cells, epithelial cells beneath skin surface (e.g., tongue, stomach, intestine, bladder, kidney).
  • Transitional Cell Carcinoma Forms in transitional epithelium or urothelium (e.g., bladder, kidneys, ureter, urethra)

Additional Cancer Types

  • Sarcoma : Forms in bone and soft tissues (muscle, fat, blood vessels, fibrous tissues) Ex: Leiomyosarcoma
  • Leukemia: Begins in blood-forming tissue of bone marrow. Types include lymphoblastic or myeloid.
  • Lymphoma: Begins in lymphocytes (T or B cells). Types include Hodgkin and Non-Hodgkin lymphoma.
  • Multiple Myeloma: Begins in plasma cells
  • Melanoma: Begins in melanocytes, specialized cells creating melanin. Risk factors include fair skin and high radiation exposure
  • Osteoma: Cancer of bone and muscle. Ex: Osteosarcoma
  • Hemangioma: Cancer of blood vessels
  • Carcinoma in situ : Uncontrolled cell growth confined to the original tissue; not metastatic.

Tumor Grading and Staging

  • Grading : Evaluates the degree to which tumor cells exhibit normal structural and functional characteristics.
  • Staging : Evaluates the size, extent, and spread of the tumor to categorize/differentiate the stages or severity(1,2,3,4), such as roman numerals. Often used in conjunction with TNM staging system.
  • TNM staging: Classification of tumor size (T), lymph node involvement (N), and presence of metastasis (M)

Assessment

  • Population-based studies: Identify regions with the highest rates of certain cancers (e.g., Australia - skin cancer, Brazil - cervical cancer).
  • Risk factors: Tobacco use, high-energy radiation, and certain viruses or bacteria increase the chances of developing cancer
  • Other factors: genetics, family history influence cancer development, race, geography and ethnicity.

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