Nucleotide Metabolism: Purines and Pyrimidines
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Questions and Answers

What is the starting material for the synthesis of flavin nucleotides?

  • Pantothenate (vitamin B5)
  • Nicotinate
  • Tryptophan
  • Riboflavin (vitamin B2) (correct)

What is the role of glutamine in the synthesis of NAD+?

  • Activating the terminal ribose –OH group by phosphorylation
  • Removing CO2 from the molecule
  • Providing the amino group for amidation (correct)
  • Donating a carbon atom for the formation of the nucleotide

What is the source of the reactive sulfur in the synthesis of CoA?

  • Pantothenate (vitamin B5)
  • Riboflavin (vitamin B2)
  • Tryptophan
  • Cysteine (correct)

What is the enzyme responsible for the removal of CO2 in the synthesis of CoA?

<p>Phosphopantothenoylcysteine decarboxylase (D)</p> Signup and view all the answers

What is the product of the reaction catalyzed by FAD pyrophosphorylase?

<p>Flavin adenine dinucleotide (FAD) (C)</p> Signup and view all the answers

What is the starting material for the synthesis of NAD+?

<p>Tryptophan (D)</p> Signup and view all the answers

What is the role of flavin cofactor in the synthesis of CoA?

<p>Removal of CO2 by phosphopantothenoylcysteine decarboxylase (B)</p> Signup and view all the answers

What is the product of the reaction catalyzed by flavokinase?

<p>Riboflavin monophosphate (D)</p> Signup and view all the answers

What is the role of AMP in the synthesis of CoA?

<p>Tacking on to the molecule to form CoA (D)</p> Signup and view all the answers

What is the essential amino acid that is converted into nicotinate?

<p>Tryptophan (D)</p> Signup and view all the answers

Flashcards

Flavin Nucleotide Synthesis: Starting Material?

Riboflavin (vitamin B2) is the starting material.

NAD+ Synthesis: Glutamine's Role?

Glutamine provides the amino group for amidation in NAD+ synthesis.

CoA Synthesis: Sulfur Source?

Cysteine is the source of reactive sulfur.

CoA Synthesis: Enzyme Removing CO2?

Phosphopantothenoylcysteine decarboxylase removes CO2.

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FAD Pyrophosphorylase Product?

FAD pyrophosphorylase produces flavin adenine dinucleotide (FAD).

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NAD+ Synthesis: Starting Material?

Tryptophan is the starting material.

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CoA Synthesis: Flavin's Role?

Flavin cofactor is needed for removal of CO2 by phosphopantothenoylcysteine decarboxylase.

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Flavokinase Reaction Product?

Riboflavin monophosphate is the product.

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CoA Synthesis: AMP's Role?

AMP tacks on to the molecule to form CoA.

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Nicotinate Synthesis: Precursor?

Tryptophan is converted into nicotinate.

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