Nucleic Acids Overview Quiz

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Questions and Answers

What is the largest molecule among the other macromolecules?

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DNA polymers can be very large molecules containing millions of nucleotides.

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What are the two types of nucleic acids?

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What is the monomer of nucleic acids?

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What are the three components of a nucleotide?

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What is the name of the sugar found in DNA?

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Match the following nitrogenous bases with their respective categories:

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DNA is double stranded, which means two strands are connected.

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Which one of the following is NOT nitrogenous bases found in DNA?

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What type of bond forms between the nitrogenous bases in DNA?

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Which of the following pairs correctly represents the base pairing rules in DNA?

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What is the purpose of DNA replication?

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DNA replication is a process by which DNA is copied into a new molecule of messenger RNA.

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RNA is single stranded.

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What are the four types of RNA?

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What type of RNA carries genetic information from DNA to the ribosomes?

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Ribosomal RNA is the most abundant type of RNA in cells.

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What type of RNA brings amino acids to the ribosomes?

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What is the role of micro RNA?

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The central dogma of molecular biology describes the flow of genetic information from DNA to RNA to protein.

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What is the process by which DNA is copied into RNA called?

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What is the process by which RNA is decoded to produce proteins called?

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Flashcards

Nucleic Acids

The largest of the four major classes of biological macromolecules, composed of nucleotides and responsible for storing and transmitting genetic information.

Nucleotide

The building block of nucleic acids, consisting of a phosphate group, a pentose sugar, and a nitrogenous base.

Deoxyribonucleic Acid (DNA)

One of the two types of nucleic acids, found in the nucleus, mitochondria, and chloroplasts, responsible for storing genetic information.

Ribonucleic Acid (RNA)

One of the two types of nucleic acids, found in the nucleus, cytoplasm, and ribosomes, involved in protein synthesis.

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Nucleotide

The molecule found in DNA and RNA that contains a phosphate group, a pentose sugar, and a nitrogenous base.

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Deoxyribose

The five-carbon sugar found in DNA; lacks an oxygen atom on the 2' carbon.

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Ribose

The five-carbon sugar found in RNA; has an oxygen atom on the 2' carbon.

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Nitrogenous Base

A nitrogen-containing molecule found in DNA and RNA that determines the genetic code. Examples include adenine, guanine, cytosine, thymine, and uracil.

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Transcription

The process by which the genetic code in DNA is copied into a new molecule of messenger RNA (mRNA).

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Translation

The process by which the genetic code in messenger RNA is decoded to produce the specific sequence of amino acids in a polypeptide chain. This process is crucial for making proteins.

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DNA Replication

The process by which DNA makes an exact copy of itself, essential for cell division and growth.

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Messenger RNA (mRNA)

A type of RNA that carries the genetic information from DNA to ribosomes, where protein synthesis occurs.

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Ribosomal RNA (rRNA)

A type of RNA that forms a major component of ribosomes, the cellular machinery responsible for protein synthesis.

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Transfer RNA (tRNA)

A type of RNA that carries amino acids to the ribosomes, where they are added to the growing polypeptide chain during protein synthesis.

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Micro RNA (miRNA)

A type of RNA that regulates gene expression by interfering with the expression of certain mRNA messages, often by inhibiting translation.

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Coding DNA

A type of DNA that is found in the nucleus of a cell and contains the coding sequences for proteins. These are the genes that are transcribed and translated.

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Non-coding DNA

A type of DNA that does not directly code for proteins. It can play regulatory roles in gene expression or have other functions.

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Codon

A sequence of three nucleotides in a DNA or RNA molecule that codes for a specific amino acid during protein synthesis.

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Transcription

The process of converting DNA into RNA, which involves copying the genetic information from DNA into RNA.

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Translation

The process of converting RNA into a protein, which involves translating the genetic code in RNA into a sequence of amino acids that make up a protein.

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Polypeptide Chain

A long chain of amino acids linked together in a specific sequence, forming a functional protein.

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Transfer RNA (tRNA)

A specific type of RNA molecule that carries amino acids to the ribosome during protein synthesis, matching up with a particular codon on the mRNA molecule.

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DNA Replication

The process by which a copy of DNA is made. It is essential for cell division, as each daughter cell receives a copy of the DNA.

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Micro RNA (miRNA) Regulation

A process that regulates gene expression by interfering with the expression of certain mRNA messages, often by inhibiting translation.

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Genetic Code

The set of instructions that directs the development, functioning, and reproduction of an organism.

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Central Dogma of Molecular Biology

The theory that genetic information is transferred from DNA to RNA and then to protein, with the protein ultimately determining a trait.

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Mutation

A change in the DNA sequence, which can lead to a change in the amino acid sequence of a protein and potentially alter the protein's function or a trait.

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Transcription

The process by which DNA is copied into RNA, which then moves to the ribosomes for protein synthesis.

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Translation

The process by which RNA is translated into protein. The genetic code in RNA is used to assemble amino acids into chains, creating a protein.

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Double Helix

The structure of DNA, which consists of two strands of nucleotides wound around each other in a helix.

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Study Notes

Nucleic Acids Overview

  • Nucleic acids are among the largest macromolecules, composed of nucleotide subunits.
  • DNA is a very large molecule, containing millions of nucleotides. The largest human chromosome (number 1) is roughly 220 million base pairs long.
  • Nucleic acids include DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).

Nucleotides

  • Nucleotides are the building blocks of nucleic acids.
  • A nucleotide consists of a phosphate group, a pentose sugar (ribose or deoxyribose), and a nitrogenous base.

Phosphate Group

  • A phosphate group has a central phosphorus atom bonded to four oxygen atoms.

Pentose Sugars

  • Pentose sugars are 5-carbon sugars.
  • Ribose is found in RNA.
  • Deoxyribose is found in DNA.

Nitrogenous Bases

  • Nitrogenous bases include purines (adenine and guanine) and pyrimidines (cytosine, thymine, and uracil).
  • DNA contains adenine, guanine, cytosine, and thymine.
  • RNA contains adenine, guanine, cytosine, and uracil.

DNA Structure and Properties

  • DNA is a double-stranded helix.
  • DNA has a deoxyribose sugar.
  • DNA bases: adenine, guanine, cytosine, thymine.
  • Adenine pairs with thymine, and guanine pairs with cytosine.
  • The bonding (adenine-thymine and guanine-cytosine) forms two hydrogen bonds or three hydrogen bonds, respectively.
  • DNA is usually found in the nucleus, but also in mitochondria and chloroplasts.

RNA Structure and Properties

  • RNA is single-stranded, it can be linear or form hairpin loops.
  • RNA has a ribose sugar.
  • RNA bases: adenine, guanine, cytosine, uracil.
  • Adenine pairs with uracil, and guanine pairs with cytosine.
  • RNA is found in the nucleus, cytoplasm, and ribosomes.

Types of RNA

  • Messenger RNA (mRNA)
  • Ribosomal RNA (rRNA)
  • Transfer RNA (tRNA)
  • Micro RNA (miRNA)

Functions of DNA

  • DNA contains the instructions an organism needs to develop, live, and reproduce.
  • DNA holds the code for proteins. Proteins, complex molecules, carry out many functions in the body.
  • DNA replication is necessary for passing genetic information to new daughter cells.

Functions of RNA

  • Involved in protein synthesis
  • mRNA carries information for protein synthesis from DNA.
  • rRNA is part of the ribosome, which assists in protein synthesis.
  • tRNA brings amino acids to the ribosome during protein synthesis.
  • miRNA regulates gene expression.

Central Dogma

  • The central dogma describes the flow of genetic information from DNA to RNA to protein to trait.
  • DNA -> mRNA -> protein -> trait
  • Transcription: DNA is copied into mRNA.
  • Translation: mRNA is decoded to produce proteins (amino acid sequences).

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