Fungal & Parasites

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Which of the following is a type of fungal infection that is commonly found in the central and Mideastern regions of the United States?

Aspergillus

Blastomycosis

Candidiasis

Coccidioidomycosis (correct)

What is the mechanism of action of the antifungal drug amphotericin B deoxycholate (Fungizone)?

Disrupts fungal cell membrane (correct)

Inhibits fungal protein synthesis

Inhibits fungal cell wall synthesis

Inhibits fungal DNA replication

Which of the following is a nursing consideration when administering amphotericin B?

Premedicate the patient to limit side effects

Use a filter when giving the non-lipid formulation

Hydrate with IV sodium chloride to limit renal damage

All of the above (correct)

A client has a severe cryptococcus infection, and the physician is considering the use of flucytosine. Which medication must flucytosine be paired with for this client?

amphotericin B Signup and view all the answers

A client is prescribed metronidazole for trichomoniasis. What is an important counseling point for the nurse to teach the client?

Do not drink alcohol during treatment and 3 days after Signup and view all the answers

A client receives a diagnosis of enterobiasis, an infection with Enterobius vermicularis. What is E. vermicularis?

Pinworm Signup and view all the answers

Match the following types of fungal infections with their associated locations:

Coccidioidomycosis = Southwest U.S. and northern Mexico Histoplasmosis = Central and Mideastern U.S. Oral candidiasis = Mouth Pneumocystosis = Lungs Signup and view all the answers

Match the following antifungal medications with their associated nursing considerations:

Amphotericin B deoxycholate (Fungizone) = Renal impairment common, organ failure, cardiac arrest, respiratory arrest Abelcet, AmBisome = Less nephrotoxic, do not use inline filter Amphotericin B = Requires premedication, use a filter if giving the non-lipid formulation Flucytosine = Must be paired with another medication Signup and view all the answers

Match the following fungal types with their descriptions:

Molds, Yeasts = Types of fungi Dermatophytes = Fungi that cause skin infections Aspergillus = Type of fungus Cryptococcus = Type of fungus Signup and view all the answers

Match the following antifungal drugs with their correct prototypes:

Amebicides = metronidazole (Flagyl) Antimalarials = chloroquine (Aralen) Anthelmintics = mebendazole (Enverm) Scabicides and Pediculicides = permethrin (Elimite, Topical Nix) Signup and view all the answers

Match the following parasites with their correct infections:

Cryptococcus = severe infection treated with flucytosine Enterobius vermicularis = infection diagnosed with enterobiasis Ameba = infection treated with metronidazole Lice = infection treated with scabicides and pediculicides Signup and view all the answers

Match the following antifungal drugs with their correct mechanisms of action:

Fluconazole (Diflucan) = disrupts membrane permeability Flucytosine = affects cell membrane, resulting in cell death Metronidazole (Flagyl) = diffuses across cell membrane, resulting in cell death Chloroquine (Aralen) = interferes with parasite DNA, RNA, and metabolism Signup and view all the answers

Match the following parasites with their correct treatments:

Worms = treated with mebendazole Ameba = treated with metronidazole Malaria = treated with chloroquine Lice = treated with permethrin Signup and view all the answers