Fungal & Parasites

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Questions and Answers

Which of the following is a type of fungal infection that is commonly found in the central and Mideastern regions of the United States?

  • Aspergillus
  • Blastomycosis
  • Candidiasis
  • Coccidioidomycosis (correct)

What is the mechanism of action of the antifungal drug amphotericin B deoxycholate (Fungizone)?

  • Disrupts fungal cell membrane (correct)
  • Inhibits fungal protein synthesis
  • Inhibits fungal cell wall synthesis
  • Inhibits fungal DNA replication

Which of the following is a nursing consideration when administering amphotericin B?

  • Premedicate the patient to limit side effects
  • Use a filter when giving the non-lipid formulation
  • Hydrate with IV sodium chloride to limit renal damage
  • All of the above (correct)

A client has a severe cryptococcus infection, and the physician is considering the use of flucytosine. Which medication must flucytosine be paired with for this client?

<p>amphotericin B (D)</p> Signup and view all the answers

A client is prescribed metronidazole for trichomoniasis. What is an important counseling point for the nurse to teach the client?

<p>Do not drink alcohol during treatment and 3 days after (A)</p> Signup and view all the answers

A client receives a diagnosis of enterobiasis, an infection with Enterobius vermicularis. What is E. vermicularis?

<p>Pinworm (A)</p> Signup and view all the answers

Match the following types of fungal infections with their associated locations:

<p>Coccidioidomycosis = Southwest U.S. and northern Mexico Histoplasmosis = Central and Mideastern U.S. Oral candidiasis = Mouth Pneumocystosis = Lungs</p> Signup and view all the answers

Match the following antifungal medications with their associated nursing considerations:

<p>Amphotericin B deoxycholate (Fungizone) = Renal impairment common, organ failure, cardiac arrest, respiratory arrest Abelcet, AmBisome = Less nephrotoxic, do not use inline filter Amphotericin B = Requires premedication, use a filter if giving the non-lipid formulation Flucytosine = Must be paired with another medication</p> Signup and view all the answers

Match the following fungal types with their descriptions:

<p>Molds, Yeasts = Types of fungi Dermatophytes = Fungi that cause skin infections Aspergillus = Type of fungus Cryptococcus = Type of fungus</p> Signup and view all the answers

Match the following antifungal drugs with their correct prototypes:

<p>Amebicides = metronidazole (Flagyl) Antimalarials = chloroquine (Aralen) Anthelmintics = mebendazole (Enverm) Scabicides and Pediculicides = permethrin (Elimite, Topical Nix)</p> Signup and view all the answers

Match the following parasites with their correct infections:

<p>Cryptococcus = severe infection treated with flucytosine Enterobius vermicularis = infection diagnosed with enterobiasis Ameba = infection treated with metronidazole Lice = infection treated with scabicides and pediculicides</p> Signup and view all the answers

Match the following antifungal drugs with their correct mechanisms of action:

<p>Fluconazole (Diflucan) = disrupts membrane permeability Flucytosine = affects cell membrane, resulting in cell death Metronidazole (Flagyl) = diffuses across cell membrane, resulting in cell death Chloroquine (Aralen) = interferes with parasite DNA, RNA, and metabolism</p> Signup and view all the answers

Match the following parasites with their correct treatments:

<p>Worms = treated with mebendazole Ameba = treated with metronidazole Malaria = treated with chloroquine Lice = treated with permethrin</p> Signup and view all the answers

True or false: Fungi can be found in soil, decaying plants, and as part of human flora?

<p>True (A)</p> Signup and view all the answers

True or false: Severe and life-threatening fungal infections are more common in immunocompromised individuals?

<p>True (A)</p> Signup and view all the answers

True or false: Amphotericin B is a polyene antifungal drug that disrupts the fungal membrane to stop reproduction?

<p>True (A)</p> Signup and view all the answers

A filter needs to be used if giving the lipid formulation Azoles (-conazole) Prototype: fluconazole (Diflucan)

<p>True (A)</p> Signup and view all the answers

Metronidazole is the drug of choice for the treatment of candida infections

<p>False (B)</p> Signup and view all the answers

Flucytosine must be paired with amphotericin B for the treatment of severe cryptococcus infection

<p>True (A)</p> Signup and view all the answers

Mebendazole is an anthelmintic drug used for the treatment of pinworm, hookworm, roundworm, and whipworm infections

<p>True (A)</p> Signup and view all the answers

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