NTN-609 Nanobiotechnology: Viral Nanoparticles and Sum-up

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What is the primary application of Viral Nanoparticles (VNPs) in the field of healthcare?

For vaccine development
For infusion and encapsulation of payloads with improved specificities for cell targeting (correct)
For diagnosis and treatment of viral diseases
For gene editing and gene therapy

What is the advantage of using plant viruses in the development of VNPs?

They are less invasive and do not generate an immune response (correct)
They are harder to engineer
They are more infectious
They are more toxic

What is the significance of the spherical shell of VNPs?

It is useful for vaccination
It is useful for gene editing
It provides a small surface area-to-mass ratio
It provides a large surface area-to-mass ratio and high stability (correct)

What is the advantage of helical VLPs over spherical VNPs?

They have a longer circulation time and efficient delivery (D) Signup and view all the answers

How can VNPs be modified and functionalized?

Through bioconjugation chemistries, encapsulation techniques, and mineralization strategies (D) Signup and view all the answers

What is the significance of protein cage architectures?

They can be used as size-constrained reaction vessels and chemical building blocks (C) Signup and view all the answers

What is the primary function of Viral Nanoparticles (VNPs)?

To serve as adaptable delivery systems for vaccines and therapeutic agents (C) Signup and view all the answers

How are Viral Nanoparticles (VNPs) typically produced?

Through precise genetic engineering and chemical conjugation (B) Signup and view all the answers

What is a characteristic of Viral Nanoparticles (VNPs)?

They possess distinct functional characteristics and immunogenic properties (B) Signup and view all the answers

Which of the following is an application of Viral Nanoparticles (VNPs)?

Drug delivery (B) Signup and view all the answers

What is the role of the Capsid Protein (CP) in Viral Nanoparticles (VNPs)?

To incorporate payload in VNPs (A) Signup and view all the answers

What is the advantage of using Viral Nanoparticles (VNPs) as nanocarriers?

They have improved biocompatibility and biodegradability (A) Signup and view all the answers

What is a common production technique for virus-like particles?

Heterologous expression in bacteria and yeast (C) Signup and view all the answers

What is the function of the interior surface of the CCMV viral capsid?

To serve as a nucleation site for crystal growth (A) Signup and view all the answers

What is the maximum diameter of the nanoparticles synthesized using the CCMV viral capsid?

24 nm (A) Signup and view all the answers

What is the characteristic of the CCMV viral capsid that allows it to undergo a pH-dependent structural transition?

Its ability to undergo gating (D) Signup and view all the answers

What is the purpose of chemical tuning and design in viral nanotechnology?

To attach and encapsulate molecules that confer different functionalities (A) Signup and view all the answers

What is the advantage of using viral nanoparticles in nanotechnology?

They can be easily modified to confer different functionalities (C) Signup and view all the answers