Chapter 44 and 10 Pharm
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Questions and Answers

Which NSAID should be avoided by patients with a Sulpha allergy?

  • Celecoxib (correct)
  • Diclofenac sodium
  • Ibuprofen
  • Nabumetone

    • Which medication is specifically mentioned for arthritis and is available over the counter as a topical cream?

  • Ibuprofen
  • Colchicine
  • Diclofenac sodium (correct)
  • Acetaminophen

    • Which medication is used for gout and works by inhibiting the reabsorption of uric acid in the kidney?

  • Ibuprofen
  • Colchicine
  • Probenecid (correct)
  • Allopurinol

    • What is a common adverse effect of antigout medications mentioned in the text?

    <p>Diarrhea</p> Signup and view all the answers

    What should patients taking NSAIDs or antigout medications do if they experience ringing in the ears, persistent GI pain, or easy bruising/bleeding?

    <p>Immediately tell their doctor</p> Signup and view all the answers

    What is one condition a patient may have that would cause us to use caution giving an opioid?

    <p>Elevated intracranial pressure</p> Signup and view all the answers

    Which medication can be an alternative for individuals who cannot take aspirin?

    <p>Acetaminophen</p> Signup and view all the answers

    What is the recommended action regarding NSAIDs prior to any procedures?

    <p>Discontinue NSAIDs 1 week prior to procedures</p> Signup and view all the answers

    Which of the following is a potential consequence of Colchicine use?

    <p>Low white blood cell count</p> Signup and view all the answers

    What is a contraindication for the use of Acetaminophen?

    <p>Liver dysfunction</p> Signup and view all the answers

    What are the main adverse effects of Opioid medications mentioned in the text?

    <p>CNS depression, respiratory depression, and severe constipation</p> Signup and view all the answers

    Which medication is stated as the antidote to Opioid overdose in the text?

    <p>Naloxone Naproxen</p> Signup and view all the answers

    What is one of the symptoms a patient may experience during opioid withdrawal according to the text?

    <p>Chills/hot flashes and joint pain</p> Signup and view all the answers

    Which medication should be avoided in children with flu-like symptoms due to the risk of Reye’s syndrome?

    <p>Aspirin</p> Signup and view all the answers

    What is the prophylactic usage of Aspirin primarily indicated for?

    <p>Cardiovascular protection</p> Signup and view all the answers

    Which medication is an antigout medication that prevents uric acid production?

    <p>Allopurinol</p> Signup and view all the answers

    What is the best course of action for patients experiencing persistent GI upset when taking NSAIDs?

    <p>Take the NSAIDs with food, milk, or antacids</p> Signup and view all the answers

    What is a potential consequence of consuming aspirin for a patient with a viral illness such as the flu?

    <p>Development of neurologic deficits</p> Signup and view all the answers

    Which medication can be used prophylactically for acute gout?

    <p>Colchicine</p> Signup and view all the answers

    Why is it important to avoid giving opioids to patients with severe asthma?

    <p>Opioids may exacerbate respiratory depression</p> Signup and view all the answers

    What can be a potential fatal skin condition associated with Allopurinol/Zyloprim use?

    <p>Exfoliative dermatitis</p> Signup and view all the answers

    Which NSAID is highlighted as being better tolerated on the gastrointestinal (GI) system compared to others?

    <p>Nabumetone</p> Signup and view all the answers

    What effect does Aspirin have concerning the risk of death after a Myocardial Infarction (MI)?

    <p>Decreases</p> Signup and view all the answers

    In which situation should caution be exercised when administering opioids?

    <p>When the patient is morbidly obese</p> Signup and view all the answers

    What is the maximum daily dose of Acetaminophen recommended for an older adult or a patient with liver disease?

    <p>2 grams per day</p> Signup and view all the answers

    Which medication is most suitable for inflammation like a sprained ankle according to the text?

    <p>Ibuprofen</p> Signup and view all the answers

    What should be the immediate action if a patient experiences respiratory depression due to opioids?

    <p>Give an opioid antagonist</p> Signup and view all the answers

    What is a key difference between NSAIDs and Acetaminophen based on the information provided?

    <p>While both are antipyretic, Acetaminophen is first line.</p> Signup and view all the answers

    What is a secondary use of opioids mentioned in the text besides pain relief?

    <p>Management of cough</p> Signup and view all the answers

    Why is it essential for patients to be educated not to crush or chew medications based on the information provided?

    <p>Crushing or chewing medications can alter their effectiveness.</p> Signup and view all the answers

    NSAIDs are most used for Analgesic, Anti-inflammatory, Antipyretic, Aspirin-Platelet inhibition

    <p>True</p> Signup and view all the answers

    Full therapeutic effect of NSAIDs may take _______ or longer.

    <p>1 week</p> Signup and view all the answers

    The maximum daily dose of Acetaminophen for a healthy adult is _____ grams per day.

    <p>3</p> Signup and view all the answers

    Opioids are most often used to alleviate _______ pain.

    <p>Moderate to severe</p> Signup and view all the answers

    Physiologic adaptation of the body to the presence of an opioid.

    <p>Physical dependence</p> Signup and view all the answers

    Opioid tolerance and physical dependence are expected with long-term opioid treatment.

    <p>True</p> Signup and view all the answers

    Physical dependance and opioid tolerance are the same as psychologic dependence

    <p>False</p> Signup and view all the answers

    A pattern of compulsive drug use characterized by a continued craving for an opioid and the need to use the opioid for effects other than pain relief.

    <p>Psychologic Dependence</p> Signup and view all the answers

    When you mix codeine sulfate with acetaminophen you now have a class ____ medication.

    <p>III</p> Signup and view all the answers

    We would use caution giving a schedule III opioid medication to a patient with

    <p>Respiratory depression</p> Signup and view all the answers

    Study Notes

    NSAIDs and Allergies

    • Patients with a sulfa allergy should avoid the NSAID Sulfasalazine.

    Arthritis Treatments

    • Topical NSAID available over the counter for arthritis: Diclofenac gel.

    Gout Management

    • Medication for gout that inhibits uric acid reabsorption: Probenecid.
    • Common adverse effect of antigout medications: Diarrhea.

    Side Effects Monitoring

    • Patients taking NSAIDs or antigout medications should report symptoms like ringing in the ears, persistent GI pain, or easy bruising/bleeding.

    Opioid Considerations

    • Caution is advised when giving opioids to patients with a history of substance use disorder.
    • Aspirin can be substituted for individuals with aspirin intolerance.

    Pre-procedure Recommendations

    • It is recommended to discontinue NSAIDs before any surgical procedures to minimize bleeding risk.

    Colchicine Risks

    • Potential consequence of colchicine use includes gastrointestinal toxicity.

    Acetaminophen Contraindications

    • Acetaminophen is contraindicated in patients with severe liver disease.

    Opioid Adverse Effects

    • Main adverse effects of opioids include respiratory depression, constipation, and sedation.

    Opioid Overdose Rescue

    • Naloxone is the antidote for opioid overdose.

    Opioid Withdrawal Symptoms

    • Symptoms during opioid withdrawal may include anxiety and irritability.

    Reye’s Syndrome

    • Aspirin should be avoided in children with flu-like symptoms due to the risk of Reye’s syndrome.

    Aspirin Prophylaxis

    • Prophylactic use of aspirin is primarily indicated for preventing cardiovascular events.

    Antigout Medications

    • Allopurinol is an antigout medication that prevents uric acid production.

    Managing GI Upset

    • For persistent GI upset from NSAIDs, switching to a buffered or enteric-coated formulation is recommended.

    Aspirin Risks with Viral Illnesses

    • Potential consequence of using aspirin with a viral illness includes increased risk of Reye's syndrome.

    Acute Gout Prophylaxis

    • Colchicine can be used prophylactically for acute gout flares.

    Opioids and Asthma

    • Avoiding opioids in patients with severe asthma is crucial due to the risk of respiratory depression.

    Skin Conditions from Allopurinol

    • A fatal skin condition associated with Allopurinol is Stevens-Johnson syndrome.

    NSAIDs and GI Tolerance

    • Ibuprofen is considered better tolerated in terms of gastrointestinal effects compared to other NSAIDs.

    Aspirin and Myocardial Infarction

    • Aspirin's effect can lower the risk of death following a myocardial infarction.

    Caution in Opioid Administration

    • Caution should be exercised when administering opioids to patients with a history of sleep apnea.

    Acetaminophen Dosage Limits

    • The maximum daily dose of acetaminophen for older adults or those with liver disease is usually limited to 2 grams.

    Inflammation Treatment

    • NSAIDs such as Ibuprofen are suitable for treating inflammation, like in sprained ankles.

    Immediate Action for Respiratory Depression

    • Immediate action for respiratory depression due to opioids includes administering naloxone and providing oxygen.

    NSAIDs vs. Acetaminophen

    • Key difference: NSAIDs provide anti-inflammatory benefits while acetaminophen primarily acts as an analgesic and antipyretic.

    Secondary Use of Opioids

    • Besides pain relief, opioids may be used to relieve cough or diarrhea.

    Medication Administration Education

    • Important for patients to understand not to crush or chew certain medications to avoid altering their release mechanisms.

    NSAIDs and Therapy Timeline

    • Full therapeutic effect of NSAIDs may take several days or longer to manifest.

    Acetaminophen Maximum Daily Dose

    • The maximum daily dose of acetaminophen for a healthy adult is 4 grams.

    Opioids and Pain Management

    • Opioids are predominantly used to alleviate acute and chronic pain.

    Opioid Tolerance and Dependence

    • Opioid tolerance indicates the body's adaptation to prolonged opioid use, which can lead to physical dependence; this should not be confused with psychological dependence.

    Codeine and Acetaminophen Combination

    • The combination of codeine sulfate with acetaminophen forms a Schedule III medication classification.

    Caution with Schedule III Opioids

    • Caution should be exercised when administering Schedule III opioids to patients with a history of substance use disorder.

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    Test your knowledge on Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) with this quiz covering their uses, contraindications, and specific medications like ibuprofen, aspirin, and acetaminophen.

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